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Report error Found 9675 Enz. Inhib. hit(s) with Target = 'D(3) dopamine receptor'
TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM476758(US10870660, Compound III-024 | US11345716, Compoun...)
Affinity DataKi:  0.0120nMAssay Description:225 nL of the solutions of the non-specific ligand or the compounds of the present invention at each concentration (in case of vehicle, final concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM476918(US10870660, Compound II-057)
Affinity DataKi:  0.0140nMAssay Description:225 nL of the solutions of the non-specific ligand or the compounds of the present invention at each concentration (in case of vehicle, final concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM593894(US11578084, Compound I'-42)
Affinity DataKi:  0.0160nMAssay Description:Buffer solution: 50 mM Tris-HCl (35409-45, Nacalai Tesque) (pH 7.4) containing 120 mM NaCl (31320-05, Nacalai Tesque), 1 mM MgCl.6HO (20909-55, Nacal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM50290221(CHEMBL80919 | Thiophene-2-carboxylic acid (4-{2-[4...)
Affinity DataKi:  0.0200nMAssay Description:Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM50063292(CHEMBL349426 | {4-[2-(4-Phenyl-piperazin-1-yl)-eth...)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity determined by measuring displacement of [3H]-spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM476915(US10870660, Compound II-047)
Affinity DataKi:  0.0220nMAssay Description:225 nL of the solutions of the non-specific ligand or the compounds of the present invention at each concentration (in case of vehicle, final concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM593791(US11578084, Compound I-074)
Affinity DataKi:  0.0250nMAssay Description:Buffer solution: 50 mM Tris-HCl (35409-45, Nacalai Tesque) (pH 7.4) containing 120 mM NaCl (31320-05, Nacalai Tesque), 1 mM MgCl.6HO (20909-55, Nacal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM476764(US10870660, Compound III-064 | US11345716, Compoun...)
Affinity DataKi:  0.0260nMAssay Description:225 nL of the solutions of the non-specific ligand or the compounds of the present invention at each concentration (in case of vehicle, final concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM50341508((S)-N-(4-(4-Phenylbenzoylamino)butyl)-N-propyl-5-a...)
Affinity DataKi:  0.0270nMAssay Description:Displacement of [3H]7-OH-DPAT from human dopamine D3 receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM593929(US11578084, Compound I-157)
Affinity DataKi:  0.0290nMAssay Description:Buffer solution: 50 mM Tris-HCl (35409-45, Nacalai Tesque) (pH 7.4) containing 120 mM NaCl (31320-05, Nacalai Tesque), 1 mM MgCl.6HO (20909-55, Nacal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM50207116(CHEMBL3905247 | US9550741, I-4)
Affinity DataKi:  0.0290nMAssay Description:Displacement of [3H]methyl-spiperone from recombinant human D3 receptor expressed in CHO cell membranes after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM593940(US11578084, Compound III-3)
Affinity DataKi:  0.0290nMAssay Description:Buffer solution: 50 mM Tris-HCl (35409-45, Nacalai Tesque) (pH 7.4) containing 120 mM NaCl (31320-05, Nacalai Tesque), 1 mM MgCl.6HO (20909-55, Nacal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM593840(US11578084, Compound I-123 | US11578084, Compound ...)
Affinity DataKi:  0.0340nMAssay Description:Buffer solution: 50 mM Tris-HCl (35409-45, Nacalai Tesque) (pH 7.4) containing 120 mM NaCl (31320-05, Nacalai Tesque), 1 mM MgCl.6HO (20909-55, Nacal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM476836(US10870660, Compound III-581 | US11345716, Compoun...)
Affinity DataKi:  0.0350nMAssay Description:225 nL of the solutions of the non-specific ligand or the compounds of the present invention at each concentration (in case of vehicle, final concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM593735(US11578084, Compound I-018)
Affinity DataKi:  0.0350nMAssay Description:Buffer solution: 50 mM Tris-HCl (35409-45, Nacalai Tesque) (pH 7.4) containing 120 mM NaCl (31320-05, Nacalai Tesque), 1 mM MgCl.6HO (20909-55, Nacal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM593733(US11578084, Compound I-016)
Affinity DataKi:  0.0390nMAssay Description:Buffer solution: 50 mM Tris-HCl (35409-45, Nacalai Tesque) (pH 7.4) containing 120 mM NaCl (31320-05, Nacalai Tesque), 1 mM MgCl.6HO (20909-55, Nacal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Rat)
Wake Forest University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50099807(CHEMBL54866 | N-(9-Benzyl-9-aza-bicyclo[3.3.1]non-...)
Affinity DataKi:  0.0400nMAssay Description:Binding affinity for dopamine receptor D3 expressed in Sf9 cells using [125I]-IABN the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM50008735((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...)
Affinity DataKi:  0.0400nMAssay Description:Displacement of [3H]methylspiperone from human recombinant D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rat)
Wake Forest University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50099821(4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (9...)
Affinity DataKi:  0.0400nMAssay Description:Binding affinity for dopamine receptor D3 expressed in Sf9 cells using [125I]-IABN the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM50008735((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...)
Affinity DataKi:  0.0400nMAssay Description:Displacement of [3H]methylspiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM50207143(CHEMBL3966842 | US9550741, II-1)
Affinity DataKi:  0.0430nMAssay Description:Displacement of [3H]methyl-spiperone from recombinant human D3 receptor expressed in CHO cell membranes after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM593890(US11578084, Compound I'-38)
Affinity DataKi:  0.0430nMAssay Description:Buffer solution: 50 mM Tris-HCl (35409-45, Nacalai Tesque) (pH 7.4) containing 120 mM NaCl (31320-05, Nacalai Tesque), 1 mM MgCl.6HO (20909-55, Nacal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM50207162(CHEMBL3918755 | US9550741, IV-1)
Affinity DataKi:  0.0430nMAssay Description:Displacement of [3H]methyl-spiperone from recombinant human D3 receptor expressed in CHO cell membranes after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rat)
Wake Forest University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50253328((S)-N-(4-((2-amino-4,5,6,7-tetrahydrobenzo[d]thiaz...)
Affinity DataKi:  0.0430nMAssay Description:Displacement of [3H]PD128907 from dopamine D3 receptor in Sprague-Dawley rat ventral striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM593802(US11578084, Compound I-085)
Affinity DataKi:  0.0440nMAssay Description:Buffer solution: 50 mM Tris-HCl (35409-45, Nacalai Tesque) (pH 7.4) containing 120 mM NaCl (31320-05, Nacalai Tesque), 1 mM MgCl.6HO (20909-55, Nacal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM50207155(CHEMBL3895540)
Affinity DataKi:  0.0460nMAssay Description:Displacement of [3H]methyl-spiperone from recombinant human D3 receptor expressed in CHO cell membranes after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM50207141(CHEMBL3920252)
Affinity DataKi:  0.0470nMAssay Description:Displacement of [3H]methyl-spiperone from recombinant human D3 receptor expressed in CHO cell membranes after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM476923(US10870660, Compound II-081 | US11345716, Compound...)
Affinity DataKi:  0.0480nMAssay Description:225 nL of the solutions of the non-specific ligand or the compounds of the present invention at each concentration (in case of vehicle, final concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM593765(US11578084, Compound I-048)
Affinity DataKi:  0.0480nMAssay Description:Buffer solution: 50 mM Tris-HCl (35409-45, Nacalai Tesque) (pH 7.4) containing 120 mM NaCl (31320-05, Nacalai Tesque), 1 mM MgCl.6HO (20909-55, Nacal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM476834(US10870660, Compound III-578 | US11345716, Compoun...)
Affinity DataKi:  0.0500nMAssay Description:225 nL of the solutions of the non-specific ligand or the compounds of the present invention at each concentration (in case of vehicle, final concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Rat)
Wake Forest University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50005120(CHEMBL274491 | N-((2S,3S)-1-Benzyl-2-methyl-pyrrol...)
Affinity DataKi:  0.0500nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM476858(US10870660, Compound III-706 | US11345716, Compoun...)
Affinity DataKi:  0.0510nMAssay Description:225 nL of the solutions of the non-specific ligand or the compounds of the present invention at each concentration (in case of vehicle, final concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM50207148(CHEMBL3932186)
Affinity DataKi:  0.0510nMAssay Description:Displacement of [3H]methyl-spiperone from recombinant human D3 receptor expressed in CHO cell membranes after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM50207154(CHEMBL3902496)
Affinity DataKi:  0.0520nMAssay Description:Displacement of [3H]methyl-spiperone from recombinant human D3 receptor expressed in CHO cell membranes after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM476924(US10870660, Compound II-084 | US11345716, Compound...)
Affinity DataKi:  0.0520nMAssay Description:225 nL of the solutions of the non-specific ligand or the compounds of the present invention at each concentration (in case of vehicle, final concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM50207113(CHEMBL3896937 | US9550741, IV-3)
Affinity DataKi:  0.0550nMAssay Description:Displacement of [3H]methyl-spiperone from recombinant human D3 receptor expressed in CHO cell membranes after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM50207094(CHEMBL3976282 | US9550741, I-2)
Affinity DataKi:  0.0560nMAssay Description:Displacement of [3H]methyl-spiperone from recombinant human D3 receptor expressed in CHO cell membranes after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM476773(US10870660, Compound III-138 | US11345716, Compoun...)
Affinity DataKi:  0.0570nMAssay Description:225 nL of the solutions of the non-specific ligand or the compounds of the present invention at each concentration (in case of vehicle, final concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM50207150(CHEMBL3933256)
Affinity DataKi:  0.0580nMAssay Description:Displacement of [3H]methyl-spiperone from recombinant human D3 receptor expressed in CHO cell membranes after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM476914(US10870660, Compound II-041)
Affinity DataKi:  0.0580nMAssay Description:225 nL of the solutions of the non-specific ligand or the compounds of the present invention at each concentration (in case of vehicle, final concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM50207158(CHEMBL3982486 | US9550741, III-2)
Affinity DataKi:  0.0580nMAssay Description:Displacement of [3H]methyl-spiperone from recombinant human D3 receptor expressed in CHO cell membranes after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM593764(US11578084, Compound I-047)
Affinity DataKi:  0.0580nMAssay Description:Buffer solution: 50 mM Tris-HCl (35409-45, Nacalai Tesque) (pH 7.4) containing 120 mM NaCl (31320-05, Nacalai Tesque), 1 mM MgCl.6HO (20909-55, Nacal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM476925(US10870660, Compound II-087)
Affinity DataKi:  0.0590nMAssay Description:225 nL of the solutions of the non-specific ligand or the compounds of the present invention at each concentration (in case of vehicle, final concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Rat)
Wake Forest University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50005120(CHEMBL274491 | N-((2S,3S)-1-Benzyl-2-methyl-pyrrol...)
Affinity DataKi:  0.0600nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM571885(US11447484, Compound I-042)
Affinity DataKi:  0.0610nMAssay Description:Buffer solution: 50 mM Tris-HCl (35409-45, Nacalai Tesque) (pH 7.4) containing 120 mM NaCl (31320-05, Nacalai Tesque), 1 mM MgCl2.6H2O (20909-55, Nac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM50207115(CHEMBL3948056)
Affinity DataKi:  0.0620nMAssay Description:Displacement of [3H]methyl-spiperone from recombinant human D3 receptor expressed in CHO cell membranes after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM593734(US11578084, Compound I-017)
Affinity DataKi:  0.0630nMAssay Description:Buffer solution: 50 mM Tris-HCl (35409-45, Nacalai Tesque) (pH 7.4) containing 120 mM NaCl (31320-05, Nacalai Tesque), 1 mM MgCl.6HO (20909-55, Nacal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Rat)
Wake Forest University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50192240(CHEMBL3941818 | US10239870, Example 278)
Affinity DataKi:  0.0630nMAssay Description:[125I]-7OH-PIPAT Binding Assay at rat native D3 receptor on membranes from rat ventral striatum. Homogenates from frozen rat brain ventral striatum (...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM476759(US10870660, Compound III-027 | US11345716, Compoun...)
Affinity DataKi:  0.0640nMAssay Description:225 nL of the solutions of the non-specific ligand or the compounds of the present invention at each concentration (in case of vehicle, final concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM476866(US10870660, Compound II-053 | US11345716, Compound...)
Affinity DataKi:  0.0670nMAssay Description:225 nL of the solutions of the non-specific ligand or the compounds of the present invention at each concentration (in case of vehicle, final concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

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