Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with Target = 'Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A,G574S]'
TargetDimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A,G574S](Human immunodeficiency virus type 1)
Georgia State University

LigandPNGBDBM517(Crixivan | CHEMBL115 | L-735, 524 | MK639 | Indina...)
Affinity DataKi:  0.550nM ΔG°:  -52.3kJ/molepH: 5.0 T: 2°CAssay Description:The Ki values were obtained from the IC50 values estimated from an inhibitor dose-response curve with the spectroscopic assay and the chromogenic sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2007
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A,G574S](Human immunodeficiency virus type 1)
Georgia State University

LigandPNGBDBM13935(N-1270 | R-V-L-r-F-E-A-Nle | (4S)-4-[(2S)-2-{[(2S)...)
Affinity DataKi:  330nM ΔG°:  -36.6kJ/molepH: 5.0 T: 2°CAssay Description:The Ki values were obtained from the IC50 values estimated from an inhibitor dose-response curve with the spectroscopic assay and the chromogenic sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2007
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A,G574S](Human immunodeficiency virus type 1)
Georgia State University

LigandPNGBDBM13936(N-1465 | Ace-T-I-Nle-r-Nle-Q-R | Ac-Thr-Ile-Nle-r-...)
Affinity DataKi:  3.30E+3nM ΔG°:  -31.0kJ/molepH: 5.0 T: 2°CAssay Description:The Ki values were obtained from the IC50 values estimated from an inhibitor dose-response curve with the spectroscopic assay and the chromogenic sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2007
Entry Details Article
PubMed