Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with Target = 'Estradiol 17-beta-dehydrogenase 1'
TargetEstradiol 17-beta-dehydrogenase 1(Rat)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50515434(CHEMBL4518587)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant rat 17beta-HSD1 expressed in HEK293 cells using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 1(Rat)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50126972(CHEMBL3629586)
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant rat 17beta HSD1 expressed in HEK293 cells using unlabeled- and labelled [2,4,6,7-3H]-E1 as substrate incubated for 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 1(Rat)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50126973(CHEMBL3629587)
Affinity DataIC50: 97nMAssay Description:Inhibition of recombinant rat 17beta HSD1 expressed in HEK293 cells using unlabeled- and labelled [2,4,6,7-3H]-E1 as substrate incubated for 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 1(Rat)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50515436(CHEMBL4441313)
Affinity DataIC50: 350nMAssay Description:Inhibition of recombinant rat 17beta-HSD1 expressed in HEK293 cells using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 1(Rat)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50515435(CHEMBL4513439)
Affinity DataIC50: 388nMAssay Description:Inhibition of recombinant rat 17beta-HSD1 expressed in HEK293 cells using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 1(Rat)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50515432(CHEMBL4447938)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of recombinant rat 17beta-HSD1 expressed in HEK293 cells using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50632044(CHEMBL5417785)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human full-length C-terminal His-tagged HSD17B11 using estradiol and NAD as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50632089(CHEMBL5307400)
Affinity DataIC50: 1.00E+4nMAssay Description:Uncompetitive inhibition of recombinant human full-length C-terminal His-tagged HSD17B11 using estradiol and NAD as substrate preincubated for 10 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed