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Report error Found 158 Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 2'
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442991(CHEMBL432537 | GNF-Pf-3777 | US10669273, Compound ...)
Affinity DataKi:  970nMAssay Description:Uncompetitive inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) in presence of va...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50514040(CHEMBL4436480)
Affinity DataKi:  1.96E+3nMAssay Description:Uncompetitive inhibition of C-terminal His6-tagged human IDO2 (14 to 420 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM48009(8-fluoranylindolo[2,1-b]quinazoline-6,12-dione | 8...)
Affinity DataKi:  3.50E+3nMAssay Description:Uncompetitive inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) in presence of va...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50514041(CHEMBL4452150)
Affinity DataKi:  4.32E+3nMAssay Description:Uncompetitive inhibition of C-terminal His6-tagged human IDO2 (14 to 420 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442987(8-Bromotryptanthrin | CHEMBL72165)
Affinity DataKi:  5.60E+3nMAssay Description:Uncompetitive inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) in presence of va...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50514038(CHEMBL4577825)
Affinity DataKi:  6.11E+3nMAssay Description:Uncompetitive inhibition of C-terminal His6-tagged human IDO2 (14 to 420 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50514035(CHEMBL4437046)
Affinity DataKi:  6.32E+3nMAssay Description:Mixed competitive inhibition of C-terminal His6-tagged human IDO2 (14 to 420 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibitio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50514043(CHEMBL4545004)
Affinity DataKi:  8.85E+3nMAssay Description:Mixed uncompetitive inhibition of C-terminal His6-tagged human IDO2 (14 to 420 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442988(CHEMBL3087009)
Affinity DataKi:  1.32E+4nMAssay Description:Mixed competitive inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) in presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50240612(CHEMBL306946 | GNF-PF-2691 | Indolo[2,1-b]quinazol...)
Affinity DataKi:  1.52E+4nMAssay Description:Uncompetitive inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) in presence of va...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50514034(CHEMBL4588805)
Affinity DataKi:  1.75E+4nMAssay Description:Uncompetitive inhibition of C-terminal His6-tagged human IDO2 (14 to 420 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50514037(CHEMBL4536439)
Affinity DataKi:  1.99E+4nMAssay Description:Noncompetitive inhibition of C-terminal His6-tagged human IDO2 (14 to 420 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442989(CHEMBL3087010)
Affinity DataKi:  2.46E+4nMAssay Description:Uncompetitive inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) in presence of va...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50514042(CHEMBL4578338)
Affinity DataKi:  2.68E+4nMAssay Description:Uncompetitive inhibition of C-terminal His6-tagged human IDO2 (14 to 420 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442994(CHEMBL312537 | US10669273, Compound 5b)
Affinity DataKi:  3.46E+4nMAssay Description:Non-competitive inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) in presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50514032(CHEMBL4471831)
Affinity DataKi:  3.69E+4nMAssay Description:Uncompetitive inhibition of C-terminal His6-tagged human IDO2 (14 to 420 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50514039(CHEMBL4584081)
Affinity DataKi:  3.91E+4nMAssay Description:Uncompetitive inhibition of C-terminal His6-tagged human IDO2 (14 to 420 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442990(CHEMBL1276265)
Affinity DataKi:  3.95E+4nMAssay Description:Uncompetitive inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) in presence of va...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50514036(CHEMBL4468741)
Affinity DataKi:  4.53E+4nMAssay Description:Noncompetitive inhibition of C-terminal His6-tagged human IDO2 (14 to 420 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50514033(CHEMBL4471895)
Affinity DataKi:  4.87E+4nMAssay Description:Uncompetitive inhibition of C-terminal His6-tagged human IDO2 (14 to 420 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442995(CHEMBL3086870)
Affinity DataKi:  1.05E+5nMAssay Description:Uncompetitive inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) in presence of va...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50241727((S)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic ac...)
Affinity DataKi:  3.00E+5nMAssay Description:Inhibition of recombinant human IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction in L-kynurenine formation using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50241727((S)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic ac...)
Affinity DataKi:  4.25E+5nMAssay Description:Competitive inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) in presence of vary...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50207089(D-1-Methyltryptophan | D-1MT | Indoximod)
Affinity DataKi:  3.30E+6nMAssay Description:Inhibition of recombinant human IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction in L-kynurenine formation using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50606909(CHEMBL5219888)
Affinity DataIC50:  112nMAssay Description:Inhibition of human IDO2More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50606907(CHEMBL5220224)
Affinity DataIC50:  134nMAssay Description:Inhibition of human IDO2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50587578(CHEMBL5091825)
Affinity DataIC50:  144nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50587578(CHEMBL5091825)
Affinity DataIC50:  144nMAssay Description:Inhibition of human IDO2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50528763(CHEMBL4472697)
Affinity DataIC50:  280nMAssay Description:Inhibition of N-terminal His-tagged human IDO2 expressed in Escherichia coli expression systemMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50562506(CHEMBL4791168)
Affinity DataIC50:  310nMAssay Description:Inhibition of N-terminal 6His-tagged recombinant human IDO2 (15 to 420 residues) expressed in Escherichia coli using L-Trp as substrate by UV absorba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50562506(CHEMBL4791168)
Affinity DataIC50:  310nMAssay Description:Inhibition of IDO2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50587572(CHEMBL5085580)
Affinity DataIC50:  362nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50606906(CHEMBL5221035)
Affinity DataIC50:  387nMAssay Description:Inhibition of human IDO2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442991(CHEMBL432537 | GNF-Pf-3777 | US10669273, Compound ...)
Affinity DataIC50:  450nMAssay Description:Inhibition of recombinant human IDO2 expressed in human U87MG cells assessed as reduction in kynurenine formation using L-tryptophan as substrate aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50528779(CHEMBL4514196)
Affinity DataIC50:  490nMAssay Description:Inhibition of N-terminal His-tagged human IDO2 expressed in Escherichia coli expression systemMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50606908(CHEMBL5221037)
Affinity DataIC50:  575nMAssay Description:Inhibition of human IDO2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50528780(CHEMBL4436582)
Affinity DataIC50:  590nMAssay Description:Inhibition of N-terminal His-tagged human IDO2 expressed in Escherichia coli expression systemMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50587576(CHEMBL5082481)
Affinity DataIC50:  689nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50126143(Epacadostat | INCB-024360)
Affinity DataIC50:  710nMAssay Description:Inhibition of N-terminal His-tagged human IDO2 expressed in Escherichia coli expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50587574(CHEMBL5090441)
Affinity DataIC50:  726nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50587566(CHEMBL5092513)
Affinity DataIC50:  794nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50587567(CHEMBL5091241)
Affinity DataIC50:  830nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50587577(CHEMBL5091415)
Affinity DataIC50:  865nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50587579(CHEMBL5091243)
Affinity DataIC50:  930nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50587573(CHEMBL5091590)
Affinity DataIC50:  947nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50587575(CHEMBL5084150)
Affinity DataIC50:  958nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50587570(CHEMBL5093816)
Affinity DataIC50:  958nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM387592(N3-(3,4- difluoro- phenyl)-7- (pyridin-4- yl)furo[...)
Affinity DataIC50: <1.00E+3nMAssay Description:Human indoleamine 2,3-dioxygenase-2 (hIDO2) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM387356(N3-(3-Chloro- 4-fluorophenyl) furo[2,3- c]pyridine...)
Affinity DataIC50: <1.00E+3nMAssay Description:Human indoleamine 2,3-dioxygenase-2 (hIDO2) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50587571(CHEMBL5078912)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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