Compile Data Set for Download or QSAR
Report error Found 1380 Enz. Inhib. hit(s) with Target = 'Low molecular weight phosphotyrosine protein phosphatase'
LigandPNGBDBM50607111(CHEMBL5218807)
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal His-tagged full length mouse LMW-PTP expressed in Escherichia coli BL21(DE3) by SDS PAGE based mass spectrometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607111(CHEMBL5218807)
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal His-tagged full length rat LMW-PTP expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607111(CHEMBL5218807)
Affinity DataIC50: 4nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 using pNPP as substrate incubated for 10 mins by microplate reader based sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50576941(CHEMBL4875137)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50607137(CHEMBL5219822)
Affinity DataIC50: 8nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 using pNPP as substrate incubated for 10 mins by microplate reader based sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50576927(CHEMBL4856707)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50607112(CHEMBL5220114)
Affinity DataIC50: 36nMAssay Description:Inhibition of N-terminal His-tagged full length mouse LMW-PTP expressed in Escherichia coli BL21(DE3) by SDS PAGE based mass spectrometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607112(CHEMBL5220114)
Affinity DataIC50: 36nMAssay Description:Inhibition of N-terminal His-tagged full length rat LMW-PTP expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607138(CHEMBL5218783)
Affinity DataIC50: 49nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 using pNPP as substrate incubated for 10 mins by microplate reader based sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607136(CHEMBL5220687)
Affinity DataIC50: 56nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 using pNPP as substrate incubated for 10 mins by microplate reader based sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607110(CHEMBL5219519)
Affinity DataIC50: 62nMAssay Description:Inhibition of N-terminal His-tagged full length mouse LMW-PTP expressed in Escherichia coli BL21(DE3) by SDS PAGE based mass spectrometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607110(CHEMBL5219519)
Affinity DataIC50: 62nMAssay Description:Inhibition of N-terminal His-tagged full length rat LMW-PTP expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50576940(CHEMBL4857535)
Affinity DataIC50: 83nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50576928(CHEMBL4855952)
Affinity DataIC50: 87nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50576921(CHEMBL4874911)
Affinity DataIC50: 104nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50576933(CHEMBL4848127)
Affinity DataIC50: 106nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50576932(CHEMBL4873827)
Affinity DataIC50: 117nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50576929(CHEMBL4859307)
Affinity DataIC50: 119nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50607139(CHEMBL5220615)
Affinity DataIC50: 121nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 using pNPP as substrate incubated for 10 mins by microplate reader based sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50576930(CHEMBL4858034)
Affinity DataIC50: 147nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50576924(CHEMBL4861843)
Affinity DataIC50: 171nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal His-tagged full length mouse LMW-PTP expressed in Escherichia coli BL21(DE3) by SDS PAGE based mass spectrometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607115(CHEMBL5220051)
Affinity DataIC50: 200nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 using pNPP as substrate incubated for 10 mins by microplate reader based sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50341993(4-((3-((3-(4-carboxybenzyl)-4-oxo-2-(phenylimino)t...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human LMW-PTPase isoform 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50576919(CHEMBL4847980)
Affinity DataIC50: 239nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50576931(CHEMBL4870698)
Affinity DataIC50: 239nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50576934(CHEMBL4868378)
Affinity DataIC50: 245nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50576926(CHEMBL4857590)
Affinity DataIC50: 288nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50607120(CHEMBL5218478)
Affinity DataIC50: 300nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 using pNPP as substrate incubated for 10 mins by microplate reader based sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607121(CHEMBL5219403)
Affinity DataIC50: 300nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 using pNPP as substrate incubated for 10 mins by microplate reader based sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal His-tagged full length rat LMW-PTP expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50576920(CHEMBL4852414)
Affinity DataIC50: 306nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant LMWPTP (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50576925(CHEMBL4846731)
Affinity DataIC50: 380nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50607117(CHEMBL5218609)
Affinity DataIC50: 400nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 using pNPP as substrate incubated for 10 mins by microplate reader based sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607118(CHEMBL5219065)
Affinity DataIC50: 400nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 using pNPP as substrate incubated for 10 mins by microplate reader based sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50341993(4-((3-((3-(4-carboxybenzyl)-4-oxo-2-(phenylimino)t...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human LMW-PTPase isoform 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM532983((3-piperidylpropyl){2-[2- (trifluoromethoxy)phenyl...)
Affinity DataIC50: 500nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM533021(US11220486, Compound G38 | 3-[2-(4-Methoxy-phenyl)...)
Affinity DataIC50: 500nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM533030(US11220486, Compound G47 | 4-{[2-(4-methoxyphenyl)...)
Affinity DataIC50: 500nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM533031(US11220486, Compound G48 | (6-methoxy(3-pyridyl))[...)
Affinity DataIC50: 500nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM533033([2-(4-methoxyphenyl)(4-quinolyl)][3- (pyrrolidinyl...)
Affinity DataIC50: 500nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM533033([2-(4-methoxyphenyl)(4-quinolyl)][3- (pyrrolidinyl...)
Affinity DataIC50: 500nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM533038(US11220486, Compound G55 | [2-(4-methoxyphenyl)(4-...)
Affinity DataIC50: 500nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM533039(US11220486, Compound G56 | [2-(4-methoxyphenyl)(4-...)
Affinity DataIC50: 500nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM533040(US11220486, Compound G57 | [2-(4-methoxyphenyl)(4-...)
Affinity DataIC50: 500nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM533041([(3-{[2-(4-methoxyphenyl)(4- quinolyl)]amino}pheny...)
Affinity DataIC50: 500nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM533071(US11220486, Compound I1 | N,N-diethyl-4-(4-((3-(pi...)
Affinity DataIC50: 500nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM533092(US11220486, Compound I22 | [(3-{[2-(3-chlorophenyl...)
Affinity DataIC50: 500nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM533099(US11220486, Compound I29 | 1-acetyl-4-[(3-{[2-(4-m...)
Affinity DataIC50: 500nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

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