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Report error Found 3757 Enz. Inhib. hit(s) with Target = 'Melatonin receptor'
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50315177(CHEMBL1091161 | N-(3-(2-(benzyloxy)-5-methoxypheny...)
Affinity DataKi:  0.000550nMAssay Description:Displacement of [3H]melatonin from human melatonin MT2 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50315171(CHEMBL1092646 | N-(3-(5-methoxy-2-(3-methoxybenzyl...)
Affinity DataKi:  0.000690nMAssay Description:Displacement of [3H]melatonin from human melatonin MT2 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50266433(CHEMBL445427 | N-(2-{5-Methoxy-2-[(2,3-dihydro-1H-...)
Affinity DataKi:  0.00100nMAssay Description:Displacement of 2-[125I]Iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50315178(CHEMBL1088825 | N-(3-(2-(benzyloxy)-5-methoxypheny...)
Affinity DataKi:  0.00103nMAssay Description:Displacement of [3H]melatonin from human melatonin MT2 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343590(CHEMBL1774531 | N-{2-[7-(1-Benzothien-3-yl)-1,6-di...)
Affinity DataKi:  0.00600nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A/1B(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50118462(2,2,2-Trifluoro-N-[2-(6-methoxy-2-phenyl-3H-inden-...)
Affinity DataKi:  0.00602nMAssay Description:Ability to inhibit 2-[125I]iodomelatonin specific binding to human melatonin receptor type 1A (MT1) expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343599(CHEMBL1774522 | N-[2-(7-Phenyl-1,6-dihydro-2H-inde...)
Affinity DataKi:  0.00650nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343598(CHEMBL1774523 | N-{2-[7-(3-Furyl)-1,6-dihydro-2H-i...)
Affinity DataKi:  0.00650nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT1 receptor expressed on CHO cells by microscintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343599(CHEMBL1774522 | N-[2-(7-Phenyl-1,6-dihydro-2H-inde...)
Affinity DataKi:  0.00650nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343601(CHEMBL1774520 | N-{2-[7-(3-Thienylmethyl)-1,6-dihy...)
Affinity DataKi:  0.00670nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50093262(CHEMBL131252 | N-(9-Methoxy-2,3-dihydro-1H-phenale...)
Affinity DataKi:  0.00800nMAssay Description:Binding affinity for human melatonin receptor type 1A, expressed in HEK-293 cells (2-[125I]-Iodomelatonin is used as radioligand)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343599(CHEMBL1774522 | N-[2-(7-Phenyl-1,6-dihydro-2H-inde...)
Affinity DataKi:  0.00820nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343599(CHEMBL1774522 | N-[2-(7-Phenyl-1,6-dihydro-2H-inde...)
Affinity DataKi:  0.00820nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT1 receptor expressed on CHO cells by microscintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343603(CHEMBL1774518 | N-[2-(7-Benzyl-1,6-dihydro-2H-inde...)
Affinity DataKi:  0.00850nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343600(CHEMBL1774521 | N-[2-(7-Bromo-1,6-dihydro-2H-inden...)
Affinity DataKi:  0.00870nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT1 receptor expressed on CHO cells by microscintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343595(CHEMBL1774526 | N-{2-[7-(3-Methoxyphenyl)-1,6-dihy...)
Affinity DataKi:  0.00900nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343598(CHEMBL1774523 | N-{2-[7-(3-Furyl)-1,6-dihydro-2H-i...)
Affinity DataKi:  0.00960nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM29611(2-Iodomelatonin | CHEMBL289233 | Melatonin,2-Iodo)
Affinity DataKi:  0.0100nMMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50114725(CHEMBL314512 | N-[2-(5-Methoxy-2-phenyl-benzofuran...)
Affinity DataKi:  0.0100nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50114718(But-3-enoic acid [2-(5-methoxy-2-phenyl-benzofuran...)
Affinity DataKi:  0.0100nMAssay Description:Binding affinity on human melatonin receptor type 1A stably transfected in human embryonic kidney (HEK 293) using 2-[125I]-iodomelatonin as radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50114703(CHEMBL287560 | N-[2-(5-Methoxy-2-phenyl-benzofuran...)
Affinity DataKi:  0.0100nMAssay Description:Binding affinity on human melatonin receptor type 1A stably transfected in human embryonic kidney (HEK 293) using 2-[125I]-iodomelatonin as radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50093275(CHEMBL132802 | N-(9-Methoxy-2,3-dihydro-1H-phenale...)
Affinity DataKi:  0.0100nMAssay Description:Binding affinity for human melatonin receptor type 1A, expressed in HEK-293 cells (2-[125I]-Iodomelatonin is used as radioligand)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343605(2,2,2-Trifluoro-N-[2-(7-isopropyl-1,6-dihydro-2H-i...)
Affinity DataKi:  0.0100nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50114703(CHEMBL287560 | N-[2-(5-Methoxy-2-phenyl-benzofuran...)
Affinity DataKi:  0.0100nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM29611(2-Iodomelatonin | CHEMBL289233 | Melatonin,2-Iodo)
Affinity DataKi:  0.0100nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343592(CHEMBL1774529 | N-{2-[7-(3-Isopropylphenyl)-1,6-di...)
Affinity DataKi:  0.0110nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343607(CHEMBL1774514 | N-[2-(7-Isopropyl-1,6-dihydro-2H-i...)
Affinity DataKi:  0.0110nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50093293(CHEMBL336054 | N-(4,9-Dimethoxy-2,3-dihydro-1H-phe...)
Affinity DataKi:  0.0120nMAssay Description:Binding affinity for human melatonin receptor type 1A, expressed in HEK-293 cells (2-[125I]-Iodomelatonin is used as radioligand)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343602(CHEMBL1774519 | N-{2-[7-(Cyclohexylmethyl)-1,6-dih...)
Affinity DataKi:  0.0120nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A/1B(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50118435(2,2,2-Trifluoro-N-[2-(6-methoxy-indan-1-yl)-ethyl]...)
Affinity DataKi:  0.0123nMAssay Description:Ability to inhibit 2-[125I]iodomelatonin specific binding to human melatonin receptor type 1A (MT1) expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343607(CHEMBL1774514 | N-[2-(7-Isopropyl-1,6-dihydro-2H-i...)
Affinity DataKi:  0.0130nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT1 receptor expressed on CHO cells by microscintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM29611(2-Iodomelatonin | CHEMBL289233 | Melatonin,2-Iodo)
Affinity DataKi:  0.0130nMAssay Description:Inhibition of 2-[125I]iodomelatonin binding to human Melatonin receptor type 1A expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50118470(CHEMBL1218 | N-[2-(1,6,7,8-Tetrahydro-2H-3-oxa-as-...)
Affinity DataKi:  0.0138nMAssay Description:Binding affinity against human Melatonin receptor type 1A (MT1)More data for this Ligand-Target Pair
TargetMelatonin receptor type 1A/1B(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50471134(CHEMBL64664)
Affinity DataKi:  0.0140nMAssay Description:Displacement of 2-[125I]iodomelatonin from melatonin receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A/1B(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50471125(CHEMBL433237)
Affinity DataKi:  0.0140nMAssay Description:Binding affinity against melatonin receptor in the quail optica tecta using 2-[125] iodomelatonin (100 pM) as labelled ligandMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343600(CHEMBL1774521 | N-[2-(7-Bromo-1,6-dihydro-2H-inden...)
Affinity DataKi:  0.0140nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50118470(CHEMBL1218 | N-[2-(1,6,7,8-Tetrahydro-2H-3-oxa-as-...)
Affinity DataKi:  0.0140nMAssay Description:Binding affinity to human MT1 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50093286(CHEMBL336509 | N-(4,9-Dimethoxy-2,3-dihydro-1H-phe...)
Affinity DataKi:  0.0150nMAssay Description:Binding affinity for human melatonin receptor type 1A, expressed in HEK-293 cells (2-[125I]-Iodomelatonin is used as radioligand)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50240440(4-P-PDOT | CHEMBL285718 | N-(4-Phenyl-1,2,3,4-tetr...)
Affinity DataKi:  0.0158nMAssay Description:Inhibition of 2-[125I]iodomelatonin binding to human melatonin receptor MT2 expressed in NIH3T3 rat fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50093279(CHEMBL340832 | N-(4,9-Dimethoxy-2,3-dihydro-1H-phe...)
Affinity DataKi:  0.0160nMAssay Description:Binding affinity for human melatonin receptor type 1A, expressed in HEK-293 cells (2-[125I]-Iodomelatonin is used as radioligand)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A/1B(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50034110(CHEMBL15060 | Melatonin,2-Phenyl | N-[2-(5-Methoxy...)
Affinity DataKi:  0.0170nMAssay Description:Binding affinity against melatonin receptor in the quail optica tecta using 2-[125] iodomelatonin (100 pM) as labelled ligandMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A/1B(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50034110(CHEMBL15060 | Melatonin,2-Phenyl | N-[2-(5-Methoxy...)
Affinity DataKi:  0.0170nMAssay Description:Binding affinity against melatonin receptor in the quail optica tecta using 2-[125] iodomelatonin as labelled ligandMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343608(CHEMBL1774513 | N-[2-(7-Isopropyl-1,6-dihydro-2H-i...)
Affinity DataKi:  0.0180nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1C(Chicken)
University College London

Curated by ChEMBL
LigandPNGBDBM50470712(CHEMBL417988)
Affinity DataKi:  0.0190nMAssay Description:Binding affinity in chicken brain membranes by using [2-125I]melatonin in a competition radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034110(CHEMBL15060 | Melatonin,2-Phenyl | N-[2-(5-Methoxy...)
Affinity DataKi:  0.0200nMMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50114703(CHEMBL287560 | N-[2-(5-Methoxy-2-phenyl-benzofuran...)
Affinity DataKi:  0.0200nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50114718(But-3-enoic acid [2-(5-methoxy-2-phenyl-benzofuran...)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50043287(CHEMBL33415 | Melatonin,2-Bromo | N-[2-(2-Bromo-5-...)
Affinity DataKi:  0.0200nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343596(CHEMBL1774525 | N-{2-[7-(2-Methoxyphenyl)-1,6-dihy...)
Affinity DataKi:  0.0200nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50114703(CHEMBL287560 | N-[2-(5-Methoxy-2-phenyl-benzofuran...)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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