Compile Data Set for Download or QSAR
Report error Found 2436 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 8'
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM29279(triazole, 4a)
Affinity DatapH: 7.8 T: 2°CAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM29280(triazole, 4b)
Affinity DatapH: 7.8 T: 2°CAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM29281(triazole, 4c)
Affinity DatapH: 7.8 T: 2°CAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM29282(triazole, 4d)
Affinity DatapH: 7.8 T: 2°CAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM29293(triazole, 3k)
Affinity DatapH: 7.8 T: 2°CAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM29279(triazole, 4a)
Affinity DataAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM29280(triazole, 4b)
Affinity DataAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM29281(triazole, 4c)
Affinity DataAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM29282(triazole, 4d)
Affinity DataAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM29308(dithioether 1,3,4-thiadiazole, 8a)
Affinity DataAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM29309(dithioether 1,3,4-thiadiazole, 8b)
Affinity DataAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM29310(dithioether 1,3,4-thiadiazole, 8c)
Affinity DataAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM29311(dithioether 1,3,4-thiadiazole, 8d)
Affinity DataAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM29312(dithioether 1,3,4-thiadiazole, 8e)
Affinity DataAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM29316(2-amino-1,3,4-thiadiazole, 10)
Affinity DataAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)
Affinity DataKd:  1.70E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM31094(PKC-412 | cid_24202429)
Affinity DataKd:  4.40E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PCBioAssay
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM13531(4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...)
Affinity DataKd:  2.40E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PCBioAssay
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM13336(4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...)
Affinity DataKd:  1.10E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM31096(CHEMBL290084 | Staurosporine | cid_451705 | US2024...)
Affinity DataKd:  220nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd:  460nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PCBioAssay
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataKd:  5.00E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM50024294(SP-600125)
Affinity DataKd:  100nMAssay Description:Average Binding Constant for JNK1; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  520nMAssay Description:Average Binding Constant for JNK1; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  11nMAssay Description:Binding affinity to JNK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd:  4.40E+3nMAssay Description:Binding affinity to JNK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataKd:  630nMAssay Description:Binding constant for JNK1 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd:  4.40E+3nMAssay Description:Binding constant for JNK1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  220nMAssay Description:Binding constant for JNK1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  11nMAssay Description:Binding constant for JNK1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM50392982(CHEMBL2152382)
Affinity DataKd:  62nMAssay Description:Binding affinity to T7-phage-tagged JNK1 by PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd:  4.40E+3nMAssay Description:Binding constant for full-length JNK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  220nMAssay Description:Binding constant for full-length JNK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM50059657(CHEMBL3393602)
Affinity DataKd:  240nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM50059655(CHEMBL3393603)
Affinity DataKd:  270nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM50059656(CHEMBL3393601)
Affinity DataKd:  240nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM13531(4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...)
Affinity DataKd:  3.10E+3nMAssay Description:Average Binding Constant for JNK1; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataKd:  3.20E+3nMAssay Description:Average Binding Constant for JNK1; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM13336(4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...)
Affinity DataKd:  1.20E+3nMAssay Description:Average Binding Constant for JNK1; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM50314070(pamapimod | 6-(2,4-difluorophenoxy)-2-{[3-hydroxy-...)
Affinity DataKd:  190nMAssay Description:Binding affinity to JNK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM50314150(Arg-Pro-Lys-Arg-Pro-Thr-Thr-Leu-Asn-Leu-Phe | CHEM...)
Affinity DataKd:  420nMAssay Description:Binding affinity to JNK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM50300690(CHEMBL576982 | N-(5-tert-Butyl-isoxazol-3-yl)-N'-{...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to JNK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to JNK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM50326054(CHEMBL1240703)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to JNK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM13535(N-(4-isopropoxyphenyl)-4-[6-methoxy-7-(3-piperidin...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to JNK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to JNK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM50314070(pamapimod | 6-(2,4-difluorophenoxy)-2-{[3-hydroxy-...)
Affinity DataKd:  190nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM50341342(6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...)
Affinity DataKd:  29nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM50342301(2-(2-(benzo[b]thiophen-3-yl)acetamido)thiophene-3-...)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to JNK1 in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM50342301(2-(2-(benzo[b]thiophen-3-yl)acetamido)thiophene-3-...)
Affinity DataKd:  3.10E+3nMAssay Description:Binding affinity to JNK1 in presence of peptide JIP1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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