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Report error Found 34 Enz. Inhib. hit(s) with Target = 'Oxysterol-binding protein 2'
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM20192((1S,2R,5S,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-...)
Affinity DataKd:  68nMpH: 7.4 T: 2°CAssay Description:Recombinant OSBP, ORP4L, or ORP4S (8 pmol) was incubated in 75 μl of binding buffer (10 mM HEPES (pH 7.4), 150 mM KCl, 2% (w/v) polyvinyl alcohol)...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOxysterol-binding protein 2 [1-181,275-916](Human)
Dalhousie University

LigandPNGBDBM20182((1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-6-hydroxy-6-me...)
Affinity DataKd:  23nMpH: 7.4 T: 2°CAssay Description:Recombinant OSBP, ORP4L, or ORP4S (8 pmol) was incubated in 75 μl of binding buffer (10 mM HEPES (pH 7.4), 150 mM KCl, 2% (w/v) polyvinyl alcohol)...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOxysterol-binding protein 2 [1-181,275-916](Human)
Dalhousie University

LigandPNGBDBM20192((1S,2R,5S,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-...)
Affinity DataKd:  60nMpH: 7.4 T: 2°CAssay Description:Recombinant OSBP, ORP4L, or ORP4S (8 pmol) was incubated in 75 μl of binding buffer (10 mM HEPES (pH 7.4), 150 mM KCl, 2% (w/v) polyvinyl alcohol)...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM20182((1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-6-hydroxy-6-me...)
Affinity DataKd:  17nMpH: 7.4 T: 2°CAssay Description:Recombinant OSBP, ORP4L, or ORP4S (8 pmol) was incubated in 75 μl of binding buffer (10 mM HEPES (pH 7.4), 150 mM KCl, 2% (w/v) polyvinyl alcohol)...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM20182((1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-6-hydroxy-6-me...)
Affinity DataKd:  54nMAssay Description:Binding affinity to human ORP4More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM20192((1S,2R,5S,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-...)
Affinity DataKd:  68nMAssay Description:Binding affinity to human ORP4More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM50617159(CHEMBL5429365)
Affinity DataKi:  51nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM50617151(CHEMBL375269 | OSW-1)
Affinity DataKi:  71nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM50617152(CEPHALOSTATIN 1 | CHEBI:69376 | Cephalostatin 1)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM50558426(CHEMBL4788348)
Affinity DataKi:  92nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM50617155(CHEMBL5405099)
Affinity DataKi:  98nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM20175((1S,2R,5S,10S,11S,14S,15S)-14-[(2S)-2-hydroxy-6-me...)
Affinity DataKi:  320nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM50617154(CHEMBL5425718)
Affinity DataKi: >360nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM20180((1S,2R,5S,10S,11S,14R,15R)-14-[(2R,5S)-5-hydroxy-6...)
Affinity DataKi:  400nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM50617170(CHEMBL5424616)
Affinity DataKi:  780nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM50617160(CHEMBL5396576)
Affinity DataKi: >870nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM20183((1S,2R,5S,10S,11S,14R,15R)-14-[(2R,6R)-7-hydroxy-6...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM50617168(CHEMBL5413783)
Affinity DataKi: >2.00E+3nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM50617153(SCHWEINFURTHIN A)
Affinity DataKi:  2.60E+3nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM20176((1S,2R,5S,10S,11S,14R,15S)-14-[(2S,3S)-3-hydroxy-6...)
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM50414647(CHEMBL560194)
Affinity DataKi: >1.50E+4nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM50617166(CHEMBL5396721)
Affinity DataKi: >2.00E+4nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM50617169(CHEMBL5421489)
Affinity DataKi: >3.00E+4nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM50854(MLS000028812 | SMR000058863 | PAXILLINE | cid_1050...)
Affinity DataKi: >3.00E+4nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM50617163(CHEMBL5404919)
Affinity DataKi: >3.00E+4nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM50617164(CHEMBL5398228)
Affinity DataKi: >3.00E+4nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM50617161(CHEMBL5406469)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM50617165(CHEMBL5437577)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM20177((1S,2R,5S,10S,11S,14R,15S)-14-[(2S,3R)-3-hydroxy-6...)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM50170651((3S,8R,9S,10R,13S,14S)-3-(2-Diethylamino-ethoxy)-1...)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM50617162(CHEMBL4174453)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM50617156(CHEMBL5419969)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM50617167(CHEMBL5438768)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetOxysterol-binding protein 2(Human)
Dalhousie University

LigandPNGBDBM50617157(CHEMBL5415841)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed