Compile Data Set for Download or QSAR
Report error Found 1988 Enz. Inhib. hit(s) with Target = 'Oxysterols receptor LXR-alpha'
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20177((1S,2R,5S,10S,11S,14R,15S)-14-[(2S,3R)-3-hydroxy-6...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human LXRalpha-LBD assessed as recruitment of co-activator peptide after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataEC50:  91nMAssay Description:Agonist activity at human LXRalpha-LBD assessed as recruitment of co-activator peptide after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50241503(CHEMBL404515 | CHEMBL511367 | 2-(3,4-dihydroxyphen...)
Affinity DataEC50:  3.50E+3nMAssay Description:Agonist activity at human LXRalpha-LBD assessed as recruitment of co-activator peptide after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataKd:  92nMAssay Description:Binding affinity to human LXRalpha-LBD by surface plasmon resonanceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50241503(CHEMBL404515 | CHEMBL511367 | 2-(3,4-dihydroxyphen...)
Affinity DataKd:  2.20E+3nMAssay Description:Binding affinity to human LXRalpha-LBD by surface plasmon resonanceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM19992(2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...)
Affinity DataEC50:  97nMpH: 7.2 T: 2°CAssay Description:FRET-based co-activator recruitment assay measures agonist activities in a 384-well plate format. Reaction mixture containing His-tagged hLXR, biotin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20131(5-(4-chlorophenyl)-2-(2,3-dimethoxyphenyl)-3-[(2,4...)
Affinity DataEC50:  2.30E+3nMpH: 7.2 T: 2°CAssay Description:FRET-based co-activator recruitment assay measures agonist activities in a 384-well plate format. Reaction mixture containing His-tagged hLXR, biotin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20132((2R)-5-(4-chlorophenyl)-2-(2,3-dimethoxyphenyl)-3-...)
Affinity DataEC50:  1.60E+3nMpH: 7.2 T: 2°CAssay Description:FRET-based co-activator recruitment assay measures agonist activities in a 384-well plate format. Reaction mixture containing His-tagged hLXR, biotin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20133(2-(2,3-dimethoxyphenyl)-5-(4-fluorophenyl)-3-[(2,4...)
Affinity DataEC50:  1.40E+3nMpH: 7.2 T: 2°CAssay Description:FRET-based co-activator recruitment assay measures agonist activities in a 384-well plate format. Reaction mixture containing His-tagged hLXR, biotin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20134(2-(2,3-dimethoxyphenyl)-5-(4-methylphenyl)-3-[(2,4...)
Affinity DataEC50:  1.40E+3nMpH: 7.2 T: 2°CAssay Description:FRET-based co-activator recruitment assay measures agonist activities in a 384-well plate format. Reaction mixture containing His-tagged hLXR, biotin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20135(5-(4-chlorophenyl)-2-(2-methoxyphenyl)-3-[(2,4,6-t...)
Affinity DataEC50:  180nMpH: 7.2 T: 2°CAssay Description:FRET-based co-activator recruitment assay measures agonist activities in a 384-well plate format. Reaction mixture containing His-tagged hLXR, biotin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20136(2-(4-fluoro-2-methoxyphenyl)-5-(4-fluorophenyl)-3-...)
Affinity DataEC50:  70nMpH: 7.2 T: 2°CAssay Description:FRET-based co-activator recruitment assay measures agonist activities in a 384-well plate format. Reaction mixture containing His-tagged hLXR, biotin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20137(2-[2-(difluoromethoxy)phenyl]-5-(4-fluorophenyl)-3...)
Affinity DataEC50:  1.90E+3nMpH: 7.2 T: 2°CAssay Description:FRET-based co-activator recruitment assay measures agonist activities in a 384-well plate format. Reaction mixture containing His-tagged hLXR, biotin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20138(5-(4-chlorophenyl)-2-(2,2-difluoro-2H-1,3-benzodio...)
Affinity DataEC50:  3.90E+3nMpH: 7.2 T: 2°CAssay Description:FRET-based co-activator recruitment assay measures agonist activities in a 384-well plate format. Reaction mixture containing His-tagged hLXR, biotin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20139(5-(4-fluorophenyl)-2-(2-methoxypyridin-3-yl)-3-[(2...)
Affinity DataEC50:  400nMpH: 7.2 T: 2°CAssay Description:FRET-based co-activator recruitment assay measures agonist activities in a 384-well plate format. Reaction mixture containing His-tagged hLXR, biotin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20140(5-(4-chlorophenyl)-3-[(2,4-difluorophenyl)carbonyl...)
Affinity DataEC50:  6.70E+3nMpH: 7.2 T: 2°CAssay Description:FRET-based co-activator recruitment assay measures agonist activities in a 384-well plate format. Reaction mixture containing His-tagged hLXR, biotin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20141(5-(3,4-difluorophenyl)-2-(2,3-dimethoxyphenyl)-3-[...)
Affinity DataEC50:  1.50E+3nMpH: 7.2 T: 2°CAssay Description:FRET-based co-activator recruitment assay measures agonist activities in a 384-well plate format. Reaction mixture containing His-tagged hLXR, biotin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20142(3-[(3,5-difluorophenyl)carbonyl]-2-(2,3-dimethoxyp...)
Affinity DataEC50:  2.10E+3nMpH: 7.2 T: 2°CAssay Description:FRET-based co-activator recruitment assay measures agonist activities in a 384-well plate format. Reaction mixture containing His-tagged hLXR, biotin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20143(2-(2,3-dimethoxyphenyl)-3-[(5-fluoro-2-methylpheny...)
Affinity DataEC50:  2.40E+3nMpH: 7.2 T: 2°CAssay Description:FRET-based co-activator recruitment assay measures agonist activities in a 384-well plate format. Reaction mixture containing His-tagged hLXR, biotin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20144(3-[(2,6-difluoro-4-methoxyphenyl)carbonyl]-2-(2,3-...)
Affinity DataEC50:  900nMpH: 7.2 T: 2°CAssay Description:FRET-based co-activator recruitment assay measures agonist activities in a 384-well plate format. Reaction mixture containing His-tagged hLXR, biotin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20145(3-[(4-bromo-2,6-difluorophenyl)carbonyl]-2-(2,3-di...)
Affinity DataEC50:  900nMpH: 7.2 T: 2°CAssay Description:FRET-based co-activator recruitment assay measures agonist activities in a 384-well plate format. Reaction mixture containing His-tagged hLXR, biotin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20146(2-(2,3-dimethoxyphenyl)-5-(4-fluorophenyl)-3-[(2,4...)
Affinity DataEC50:  700nMpH: 7.2 T: 2°CAssay Description:FRET-based co-activator recruitment assay measures agonist activities in a 384-well plate format. Reaction mixture containing His-tagged hLXR, biotin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20155((2S)-5-(4-chlorophenyl)-2-(2,3-dimethoxyphenyl)-3-...)
Affinity DataAssay Description:SPA assays were run in displacement mode using 30 nM [3H]-GW3965. Ligands were tested in 12-point dose-response curves starting at 20 uM. IC50 values...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20155((2S)-5-(4-chlorophenyl)-2-(2,3-dimethoxyphenyl)-3-...)
Affinity DataAssay Description:FRET-based co-activator recruitment assay measures agonist activities in a 384-well plate format. Reaction mixture containing His-tagged hLXR, biotin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20157(GSK3987 Analogue | 1-benzyl-3-phenyl-4-(phenylamin...)
Affinity DataEC50:  100nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20158(GSK3987 Analogue | 1-benzyl-3-[(4-chlorophenyl)ami...)
Affinity DataEC50:  130nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20159(1-ethyl-3-[(4-methoxyphenyl)amino]-4-phenyl-2,5-di...)
Affinity DataEC50:  300nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20160(3-[(4-methoxyphenyl)amino]-1,4-diphenyl-2,5-dihydr...)
Affinity DataEC50:  275nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20161(3-[(4-methoxyphenyl)amino]-1-methyl-4-phenyl-2,5-d...)
Affinity DataEC50:  575nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM19992(2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...)
Affinity DataEC50:  80nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataEC50:  55nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20156(Substituted Maleimide, 4 | 1-benzyl-3-[(4-methoxyp...)
Affinity DataEC50:  50nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20162(GSK3987 Analogue | 1-ethyl-3-phenyl-4-(phenylamino...)
Affinity DataEC50:  890nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20163(3-[(4-chlorophenyl)amino]-1-ethyl-4-phenyl-2,5-dih...)
Affinity DataEC50:  725nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM8293(JMC485419 Compound 12 | 1-methyl-3-phenyl-4-(pheny...)
Affinity DataEC50:  1.59E+3nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20164(CHEMBL434302 | (1S,2R,5S,10S,11S,14R,15R)-14-[(2R)...)
Affinity DataEC50:  95nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataEC50:  60nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20165(3-(3-{[(3,4-dimethoxyphenyl)methyl](2,2-diphenylet...)
Affinity DataEC50:  260nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20166(2-(3-{3-[(2,2-diphenylethyl)[(4-methoxyphenyl)meth...)
Affinity DataEC50:  260nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20167(2-(3-{3-[(2,2-diphenylethyl)[(4-methoxyphenyl)meth...)
Affinity DataEC50:  860nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20168(2-[3-(3-{[(2,4-dimethoxyphenyl)methyl](2,2-dipheny...)
Affinity DataEC50:  660nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20169(2-(3-{3-[(2,2-diphenylethyl)[(3-fluoro-4-methoxyph...)
Affinity DataEC50:  250nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20170(2-(3-{3-[(2,2-diphenylethyl)[(2-fluoro-4-methoxyph...)
Affinity DataEC50:  190nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20171(2-(3-{3-[(2,2-diphenylethyl)({[3-(trifluoromethyl)...)
Affinity DataEC50:  85nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20172(2-(3-{3-[(2,2-diphenylethyl)({[4-fluoro-3-(trifluo...)
Affinity DataEC50:  85nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20173(2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...)
Affinity DataEC50:  45nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM19992(2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...)
Affinity DataEC50:  125nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20164(CHEMBL434302 | (1S,2R,5S,10S,11S,14R,15R)-14-[(2R)...)
Affinity DataEC50:  460nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20174((1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-4-[(2R)-3,3-di...)
Affinity DataEC50:  670nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20175((1S,2R,5S,10S,11S,14S,15S)-14-[(2S)-2-hydroxy-6-me...)
Affinity DataEC50:  470nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
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