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Report error Found 474 Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 4'
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)
Affinity DataKi:  27.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50300129(CHEMBL572528 | CIBACRON BLUE | Cibacron Blue 3Ga)
Affinity DataKi:  39.2nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Rat)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50029031(1-Amino-4-{4-[4-chloro-6-(3-sulfo-phenylamino)-[1,...)
Affinity DataKi:  46.2nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50370141(TNP-ATP)
Affinity DataKi:  49nMAssay Description:Competitive antagonist activity at human P2X4 receptor expressed in 1321N1 cell membrane assessed as inhibition of [35S]ATPgammaS binding by scintill...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM85044(Bromphenol blue | Brophenol Blue | CAS_115-39-9 | ...)
Affinity DataKi:  78.3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Rat)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50300129(CHEMBL572528 | CIBACRON BLUE | Cibacron Blue 3Ga)
Affinity DataKi:  128nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50000029(4-Methyl-8-{4-methyl-3-[3-(3-{3-[2-methyl-5-(4,6,8...)
Affinity DataKi:  178nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Rat)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM85044(Bromphenol blue | Brophenol Blue | CAS_115-39-9 | ...)
Affinity DataKi:  302nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Rat)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50000029(4-Methyl-8-{4-methyl-3-[3-(3-{3-[2-methyl-5-(4,6,8...)
Affinity DataKi:  500nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Rat)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)
Affinity DataKi:  500nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50000029(4-Methyl-8-{4-methyl-3-[3-(3-{3-[2-methyl-5-(4,6,8...)
Affinity DataKi:  5.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM85682(CAS_5311315 | NF279 | NSC_5311315)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM85730(CAS_5311313 | NF023 | NSC_5311313)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50506203(CHEMBL4452312)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50506156(CHEMBL4471140)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50506173(CHEMBL4589444)
Affinity DataIC50:  5nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50506179(CHEMBL4579583)
Affinity DataIC50:  8nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50506184(CHEMBL4447043)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50506180(CHEMBL4556573)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50506187(CHEMBL4522504)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50506178(CHEMBL4555657)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50506201(CHEMBL4516176)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50506183(CHEMBL4521017)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50506172(CHEMBL4563994)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50506185(CHEMBL4438327)
Affinity DataIC50:  24nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM366072(5-[4-[5-(2-Methoxybenzyl)-1H-tetrazol-1-yl]phenyl]...)
Affinity DataIC50:  25nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50506191(CHEMBL4439570)
Affinity DataIC50:  26nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50506169(CHEMBL4535761)
Affinity DataIC50:  27nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50506162(CHEMBL4463320)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM366073(5-[4-[5-(2-Hydroxybenzyl)-1H-tetrazol-1-yl]phenyl]...)
Affinity DataIC50:  37nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50506157(CHEMBL4517831)
Affinity DataIC50:  37nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50598326(CHEMBL5206892)
Affinity DataIC50:  39nMAssay Description:Antagonist activity against human P2X4R stably transfected in human 1321N1 cells incubated for 30 mins by Fura-2 AM staining based calcium influx ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM366069(US9873683, Example 79)
Affinity DataIC50:  39nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50506198(CHEMBL4539658)
Affinity DataIC50:  39nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50596624(CHEMBL5204261)
Affinity DataIC50:  40nMAssay Description:Negative allosteric modulation activity at human P2X4 receptor expressed in human 1321N1 cells assessed as reduction in intracellular Ca2+ influx inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50540434(CHEMBL4640175)
Affinity DataIC50:  43nMAssay Description:Antagonist activity at human P2X4 receptor expressed in human 1321N1 cells assessed as inhibition of ATP-induced cytosolic calcium influx preincubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM366075(5-[4-(5-Phenethyl-1H-tetrazol-1-yl)phenyl]-1H-naph...)
Affinity DataIC50:  44nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50506166(CHEMBL4474747)
Affinity DataIC50:  45nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50430156(CHEMBL2338695)
Affinity DataIC50:  49nMAssay Description:Antagonist activity at human P2X4 receptor expressed in human 1321N1 cells assessed as inhibition of ATP-induced cytosolic calcium influx preincubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM365870(US9873683, Example 31)
Affinity DataIC50:  51nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50506204(CHEMBL4443234)
Affinity DataIC50:  52nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM366062(US9873683, Example 67)
Affinity DataIC50:  53nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM366049(US9873683, Example 43)
Affinity DataIC50:  53nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM393615(US09969700, 173)
Affinity DataIC50:  54nMAssay Description:Antagonist activity at human P2X4 receptor expressed in HEK cells assessed as reduction in ATP induced calcium influxMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50598322(CHEMBL5200114)
Affinity DataIC50:  55nMAssay Description:Antagonist activity against human P2X4R stably transfected in human 1321N1 cells incubated for 30 mins by Fura-2 AM staining based calcium influx ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM393615(US09969700, 173)
Affinity DataIC50:  64nMAssay Description:The P2X4 receptor antagonist activity of the compounds of the present invention was measured as follows. The 1321N1 cells stably expressing human P2X...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM393615(US09969700, 173)
Affinity DataIC50:  64nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influx incubated for 15 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50506195(CHEMBL4438981)
Affinity DataIC50:  67nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM366057(US9873683, Example 61)
Affinity DataIC50:  74nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM50506163(CHEMBL4561582)
Affinity DataIC50:  75nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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