Compile Data Set for Download or QSAR
Report error Found 835 Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily A member 5'
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50067878(9-Methoxy-furo[3',2':4,5]benzo[1,2-b][1,4]oxazin-3...)
Affinity DataKd:  2.70E+5nMAssay Description:Blockade of peak K+ currents against Kv1.5 geneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50067880(4-methoxy-7H-furo[3,2-g]chromen-7-one | 5-methoxyp...)
Affinity DataKd:  1.77E+5nMAssay Description:Blockade of peak K+ currents against Kv1.5 geneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50182585(5-acetyl-7-(4'-bromo)benzyloxy-6-hydroxy-4-methoxy...)
Affinity DataEC50:  900nMAssay Description:Effect on blockade of Kv1.5 channelMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50182597(5-acetyl-4,7-benzyloxy-6-hydroxybenzofuran | CHEMB...)
Affinity DataEC50:  5.00E+3nMAssay Description:Effect on blockade of Kv1.5 channelMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50182587(5-acetyl-4-(4'-chloro)benzyloxy-6-hydroxy-7-methox...)
Affinity DataEC50:  700nMAssay Description:Effect on blockade of Kv1.5 channelMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50538344(CHEMBL4633246)
Affinity DataEC50: >1.10E+4nMAssay Description:Inhibition of human Kv1.5 by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50235240(CHEMBL4065169)
Affinity DataIC50: 9nMAssay Description:Inhibition of Kv1.5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50235250(CHEMBL4104525)
Affinity DataIC50: 11nMAssay Description:Inhibition of Kv1.5 mediated ultra-rapid delayed rectifier current Ikur in human atrial myocytes by voltage-patch clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50235240(CHEMBL4065169)
Affinity DataIC50: 11nMAssay Description:Inhibition of Kv1.5 mediated ultra-rapid delayed rectifier current Ikur in human atrial myocytes by voltage-patch clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50301472(7-(3,4-dichlorophenyl)-6-(5-fluoro-1-methyl-1H-ben...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50194360((E)-thyl-1-methyl-6,7-dihydro-1H-indol-4(5H)-one O...)
Affinity DataIC50: 21nMAssay Description:Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50022107(CHEMBL3298226)
Affinity DataIC50: 22nMAssay Description:Inhibition of human Kv1.5 expressed in mouse L929 cells assessed as inhibition of currentMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50022108(CHEMBL3298228)
Affinity DataIC50: 23nMAssay Description:Inhibition of human Kv1.5 expressed in mouse L929 cells assessed as inhibition of currentMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50235255(CHEMBL4085436)
Affinity DataIC50: 23nMAssay Description:Inhibition of Kv1.5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50120918(CHEMBL3356073)
Affinity DataIC50: 24nMAssay Description:Inhibition of human KV1.5 expressed in mouse L929 cells assessed as decrease in ultrarapid potassium current amplitudeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50022109(CHEMBL3298224)
Affinity DataIC50: 25nMAssay Description:Inhibition of human Kv1.5 expressed in mouse L929 cells assessed as inhibition of currentMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50235259(CHEMBL4105245)
Affinity DataIC50: 26nMAssay Description:Inhibition of Kv1.5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50120913(CHEMBL3622361)
Affinity DataIC50: 28nMAssay Description:Inhibition of human KV1.5 expressed in mouse L929 cells assessed as decrease in ultrarapid potassium current amplitudeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50235250(CHEMBL4104525)
Affinity DataIC50: 29nMAssay Description:Inhibition of Kv1.5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50120899(CHEMBL3622355)
Affinity DataIC50: 30nMAssay Description:Inhibition of human KV1.5 expressed in mouse L929 cells assessed as decrease in ultrarapid potassium current amplitudeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50301473(7-(3,4-dichlorophenyl)-6-(5-fluoro-1-methyl-1H-ben...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50315563({[(1S,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl](p...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human Kv1.5 channel expressed in CHO cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50235275(CHEMBL4062996)
Affinity DataIC50: 30nMAssay Description:Inhibition of Kv1.5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50120908(CHEMBL3623054)
Affinity DataIC50: 32nMAssay Description:Inhibition of human KV1.5 expressed in mouse L929 cells assessed as decrease in ultrarapid potassium current amplitudeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50099581(N-[3-(4-Ethyl-benzenesulfonylamino)-2-hydroxy-inda...)
Affinity DataIC50: 33nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50235253(CHEMBL4075394)
Affinity DataIC50: 33nMAssay Description:Inhibition of Kv1.5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50120904(CHEMBL3622346)
Affinity DataIC50: 34nMAssay Description:Inhibition of human KV1.5 expressed in mouse L929 cells assessed as decrease in ultrarapid potassium current amplitudeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50120917(CHEMBL3356074)
Affinity DataIC50: 34nMAssay Description:Inhibition of human KV1.5 expressed in mouse L929 cells assessed as decrease in ultrarapid potassium current amplitudeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50194539(4-(3-(2-fluorophenyl)propanamido)-N,N-diisopropyl-...)
Affinity DataIC50: 36nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50430217(CHEMBL2331989)
Affinity DataIC50: 37nMAssay Description:Antagonist activity at human Kv1.5 expressed in mouse L929 cells assessed as inhibition of delayed rectifier repolarization current by patch clamp as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50534219(CHEMBL4521294)
Affinity DataIC50: 40nMAssay Description:Inhibition of human Kv1.5 transfected in mouse LTK cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50235254(CHEMBL4095750)
Affinity DataIC50: 41nMAssay Description:Inhibition of Kv1.5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50022110(CHEMBL3298140)
Affinity DataIC50: 43nMAssay Description:Inhibition of human Kv1.5 expressed in mouse L929 cells assessed as inhibition of currentMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50022110(CHEMBL3298140)
Affinity DataIC50: 43nMAssay Description:Inhibition of human KV1.5 expressed in mouse L929 cells assessed as decrease in ultrarapid potassium current amplitudeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50376745(CHEMBL260684)
Affinity DataIC50: 46nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells assessed as blockade of ultra rapidly activating potassium current by voltage clamp t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50239227(US10214511, Example 7 | CHEMBL4094440 | US10676460...)
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human Kv1.5 expressed in mouse L929 cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50120907(CHEMBL3623053)
Affinity DataIC50: 47nMAssay Description:Inhibition of human KV1.5 expressed in mouse L929 cells assessed as decrease in ultrarapid potassium current amplitudeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50301471(7-(3,4-dichlorophenyl)-6-(5-fluoro-1-propyl-1H-ben...)
Affinity DataIC50: 48nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50430216(CHEMBL2331990)
Affinity DataIC50: 48nMAssay Description:Antagonist activity at human Kv1.5 expressed in mouse L929 cells assessed as inhibition of delayed rectifier repolarization current by patch clamp as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50306906(((R)-7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropy...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50099581(N-[3-(4-Ethyl-benzenesulfonylamino)-2-hydroxy-inda...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells assessed as blockade of ultra rapidly activating potassium current by voltage clamp t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50534218(CHEMBL4532101)
Affinity DataIC50: 50nMAssay Description:Inhibition of human Kv1.5 transfected in mouse LTK cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50534225(CHEMBL4450487)
Affinity DataIC50: 50nMAssay Description:Inhibition of human Kv1.5 transfected in mouse LTK cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50120903(CHEMBL3622360)
Affinity DataIC50: 52nMAssay Description:Inhibition of human KV1.5 expressed in mouse L929 cells assessed as decrease in ultrarapid potassium current amplitudeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50120916(CHEMBL3623052)
Affinity DataIC50: 52nMAssay Description:Inhibition of human KV1.5 expressed in mouse L929 cells assessed as decrease in ultrarapid potassium current amplitudeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50120901(CHEMBL3622358)
Affinity DataIC50: 55nMAssay Description:Inhibition of human KV1.5 expressed in mouse L929 cells assessed as decrease in ultrarapid potassium current amplitudeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50235260(CHEMBL4088894)
Affinity DataIC50: 56nMAssay Description:Inhibition of Kv1.5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50211550((3S,4R)-4-(N-butyl-4-ethylphenylsulfonamido)-3-hyd...)
Affinity DataIC50: 57nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50301469(6-(5-chloro-1-ethyl-1H-benzo[d]imidazol-2-yl)-7-(3...)
Affinity DataIC50: 57nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50430219(CHEMBL2331987)
Affinity DataIC50: 59nMAssay Description:Antagonist activity at human Kv1.5 expressed in mouse L929 cells assessed as inhibition of delayed rectifier repolarization current by patch clamp as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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