Report error Found 18634 Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily H member 2'
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 1.07E+5nMAssay Description:Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Mode of action, Concentration-Response Relationship Observed Source (MLPCN Center Name)...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataKd: >1.00E+5nMAssay Description:Compounds were dissolved in DMSO to a stock concentration of 10 mM and tested in 10-dose IC50 mode, in triplicate, with a 3-fold serial dilution star...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataKd: 8.90E+4nMAssay Description:Compounds were dissolved in DMSO to a stock concentration of 10 mM and tested in 10-dose IC50 mode, in triplicate, with a 3-fold serial dilution star...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataKd: 33.3nMAssay Description:Compounds were dissolved in DMSO to a stock concentration of 10 mM and tested in 10-dose IC50 mode, in triplicate, with a 3-fold serial dilution star...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataKd: >1.00E+5nMAssay Description:Compounds were dissolved in DMSO to a stock concentration of 10 mM and tested in 10-dose IC50 mode, in triplicate, with a 3-fold serial dilution star...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataKd: 8.90E+4nMAssay Description:Compounds were dissolved in DMSO to a stock concentration of 10 mM and tested in 10-dose IC50 mode, in triplicate, with a 3-fold serial dilution star...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataKd: 33.3nMAssay Description:Compounds were dissolved in DMSO to a stock concentration of 10 mM and tested in 10-dose IC50 mode, in triplicate, with a 3-fold serial dilution star...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 5.00E+3nMAssay Description:Effect on blockade of Kv11.1 channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 1.50E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 1.41E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataKd: 86nMAssay Description:Binding affinity to human Kv11.1 expressed in HEK293 cell membranes assessed as binding affinity constant by [3H]dofetilide competition association a...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 2.50E+4nMAssay Description:Inhibition of hERG by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataKd: 41nMAssay Description:Binding affinity to human Kv11.1 expressed in HEK293 cell membranes assessed as binding affinity constant by [3H]dofetilide competition association a...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 1.30E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 2.30E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataKd: 1.81E+3nMAssay Description:Binding affinity to human Kv11.1 expressed in HEK293 cell membranes assessed as binding affinity constant by [3H]dofetilide competition association a...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataKd: 1.19E+3nMAssay Description:Binding affinity to human Kv11.1 expressed in HEK293 cell membranes assessed as binding affinity constant by [3H]dofetilide competition association a...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 9.60E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells measured by Patch-clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataKd: 36nMAssay Description:Binding affinity to human Kv11.1 expressed in HEK293 cell membranes assessed as binding affinity constant by [3H]dofetilide competition association a...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataKd: 4nMAssay Description:Binding affinity to human Kv11.1 expressed in HEK293 cell membranes assessed as binding affinity constant by [3H]dofetilide competition association a...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 1.10E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells measured by Patch-clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 1.27E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 1.00E+4nMAssay Description:Activity at human ERG expressed in CHO cells by patch-clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataKd: 12nMAssay Description:Binding affinity to human Kv11.1 expressed in HEK293 cell membranes assessed as binding affinity constant by [3H]dofetilide competition association a...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 780nMAssay Description:Inhibition of human ERG expressed in CHO cells measured by Patch-clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataKd: 0.440nMAssay Description:Binding affinity to human Kv11.1 expressed in HEK293 cell membranes assessed as binding affinity constant by [3H]dofetilide competition association a...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataKd: 37nMAssay Description:Binding affinity to human Kv11.1 expressed in HEK293 cell membranes assessed as binding affinity constant by [3H]dofetilide competition association a...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: <3.00E+4nMAssay Description:Inhibition of hERG by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 500nMAssay Description:Inhibition of hERG by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 2.10E+4nMAssay Description:Inhibition of hERG by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 5.00E+3nMAssay Description:Activity at human ERG expressed in CHO cells by patch-clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 3.98E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 3.30E+3nMAssay Description:Activity at human ERG expressed in CHO cells by patch-clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataKd: 4.26E+3nMAssay Description:Binding affinity to human Kv11.1 expressed in HEK293 cell membranes assessed as binding affinity constant by [3H]dofetilide competition association a...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataKd: 8.88E+3nMAssay Description:Binding affinity to human Kv11.1 expressed in HEK293 cell membranes assessed as binding affinity constant by [3H]dofetilide competition association a...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 3.40E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataKd: 103nMAssay Description:Binding affinity to human Kv11.1 expressed in HEK293 cell membranes assessed as binding affinity constant by [3H]dofetilide competition association a...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 2.28E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 7.00E+3nMAssay Description:Inhibition of human ERG by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataKd: 637nMAssay Description:Binding affinity to human Kv11.1 expressed in HEK293 cell membranes assessed as binding affinity constant by [3H]dofetilide competition association a...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 2.75E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells at -80 mV holding potential assessed as reduction in tail current amplitude by conventional patch c...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 1.00E+4nMAssay Description:Activity at human ERG expressed in CHO cells by patch-clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 1.70E+4nMAssay Description:Inhibition of hERG by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 9.00E+3nMAssay Description:Effect on blockade of Kv11.1 channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Johns Hopkins Ion Channel Center
Curated by PubChem BioAssay
Affinity DataEC50: 8.70E+4nMAssay Description:Inhibition of hERG by fluorescence polarization assayMore data for this Ligand-Target Pair
