Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 3623 Enz. Inhib. hit(s) with Target = 'Progesterone receptor'
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336931(CHEMBL1672547 | N-(3-(4-cyano-3-fluorophenyl)-1-is...)
Affinity DataKi:  0.214nMAssay Description:Displacement of [3H]methyltrienolone from human progesterone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataKi:  0.251nMAssay Description:Inhibition of 4 nM progesterone-stimulated transactivation of MMTV-Luc reporter in CV-1 cells expressing PR-BMore data for this Ligand-Target Pair
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336933(CHEMBL1672541 | N-(3-(4-cyano-3-methylphenyl)-1-is...)
Affinity DataKi:  0.298nMAssay Description:Displacement of [3H]methyltrienolone from human progesterone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50062443(5-(4-Chloro-phenyl)-9-fluoro-2,2,4-trimethyl-2,5-d...)
Affinity DataKi:  0.320nMAssay Description:The binding affinity measured using baculovirus-expressed hPR-A in sf21 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336930((S)-N-(1-sec-butyl-3-(4-cyanophenyl)-1H-indol-6-yl...)
Affinity DataKi:  0.320nMAssay Description:Displacement of [3H]methyltrienolone from human progesterone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50062432(5-(3-Chloro-phenyl)-9-fluoro-2,2,4-trimethyl-2,5-d...)
Affinity DataKi:  0.320nMAssay Description:The binding affinity measured using baculovirus-expressed hPR-A in sf21 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50062432(5-(3-Chloro-phenyl)-9-fluoro-2,2,4-trimethyl-2,5-d...)
Affinity DataKi:  0.320nMAssay Description:Compound was evaluated for its binding affinity against baculovirus expressed Progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50067678((6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-di...)
Affinity DataKi:  0.339nMAssay Description:Displacement of [3H]progesterone from Progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50062444(9-Chloro-5-(3-fluoro-phenyl)-2,2,4-trimethyl-2,5-d...)
Affinity DataKi:  0.340nMAssay Description:The binding affinity measured using baculovirus-expressed hPR-A in sf21 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50067678((6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-di...)
Affinity DataKi:  0.340nMAssay Description:The binding affinity measured using baculovirus-expressed hPR-A in sf21 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50067678((6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-di...)
Affinity DataKi:  0.340nMAssay Description:Binding affinity was determined against hPR-A (human progesterone receptor) using progesterone radioligand in competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50129152((6S,8S,10R,14S,15S)-17-Acetyl-6,10-dimethyl-13-(R)...)
Affinity DataKi:  0.340nMAssay Description:Binding affinity to human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50067678((6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-di...)
Affinity DataKi:  0.340nMAssay Description:Compound was evaluated for its binding affinity against baculovirus expressed Progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50067678((6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-di...)
Affinity DataKi:  0.340nMAssay Description:Binding affinity towards human progesterone receptor A isoform using progesterone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50067678((6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-di...)
Affinity DataKi:  0.340nMAssay Description:The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50067678((6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-di...)
Affinity DataKi:  0.340nMAssay Description:Binding affinity against human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50062427(9-Fluoro-2,2,4-trimethyl-5-m-tolyl-2,5-dihydro-1H-...)
Affinity DataKi:  0.370nMAssay Description:The binding affinity measured using baculovirus-expressed hPR-A in sf21 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50151069((4R)-4-[(1S,2S,7R,9R,10R,11S,14R,15R,16S)-5-({[2-(...)
Affinity DataKi:  0.390nMAssay Description:Inhibition of human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50065585(5-(4-Chloro-3-methyl-phenyl)-9-fluoro-2,2,4-trimet...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity for human progesterone receptor isoform A expressed in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50065585(5-(4-Chloro-3-methyl-phenyl)-9-fluoro-2,2,4-trimet...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity for human progesterone receptor isoform A expressed in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50062415(5-(4-Chloro-3-fluoro-phenyl)-2,2,4-trimethyl-2,5-d...)
Affinity DataKi:  0.410nMAssay Description:The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50133141(9-Fluoro-2,2,4-trimethyl-5-[1-(3-methyl-pyridin-2-...)
Affinity DataKi:  0.420nMAssay Description:Binding affinity towards human progesterone receptor A isoform using progesterone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50062406(5-(3-Chloro-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H...)
Affinity DataKi:  0.430nMAssay Description:The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50072701(9-Chloro-2,2,4,5-tetramethyl-2,5-dihydro-1H-6-oxa-...)
Affinity DataKi:  0.440nMAssay Description:Binding affinity was determined against hPR-A (human progesterone receptor) using progesterone radioligand in competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50072701(9-Chloro-2,2,4,5-tetramethyl-2,5-dihydro-1H-6-oxa-...)
Affinity DataKi:  0.440nMAssay Description:Compound was evaluated for its binding affinity against baculovirus expressed Progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50062430(9-Chloro-5-(3-chloro-phenyl)-2,2,4-trimethyl-2,5-d...)
Affinity DataKi:  0.480nMAssay Description:The binding affinity measured using baculovirus-expressed hPR-A in sf21 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50062430(9-Chloro-5-(3-chloro-phenyl)-2,2,4-trimethyl-2,5-d...)
Affinity DataKi:  0.480nMAssay Description:Binding affinity for human progesterone receptor isoform A expressed in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50410188(CHEMBL2096708)
Affinity DataKi:  0.480nMAssay Description:Inhibition of human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50367916(METHYLTRIENOLONE | Metribolone | R-1881)
Affinity DataKi:  0.490nMAssay Description:Displacement of [3H]-methyltrienolone from progesterone receptor (unknown origin) expressed in HEK293 cell lysate incubated overnight by microbeta sc...More data for this Ligand-Target Pair
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50062429(5-(4-Chloro-3-methyl-phenyl)-9-fluoro-2,2,4-trimet...)
Affinity DataKi:  0.490nMAssay Description:Binding affinity for human progesterone receptor isoform A expressed in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50062429(5-(4-Chloro-3-methyl-phenyl)-9-fluoro-2,2,4-trimet...)
Affinity DataKi:  0.490nMAssay Description:The binding affinity measured using baculovirus-expressed hPR-A in sf21 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50062439(9-Chloro-5-(4-chloro-3-methyl-phenyl)-2,2,4-trimet...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity for human progesterone receptor isoform A expressed in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50062439(9-Chloro-5-(4-chloro-3-methyl-phenyl)-2,2,4-trimet...)
Affinity DataKi:  0.5nMAssay Description:The binding affinity measured using baculovirus-expressed hPR-A in sf21 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50151059(2-[(4R)-4-[(1S,2S,7R,9R,10R,11S,14R,15R,16S)-5-[2-...)
Affinity DataKi:  0.530nMAssay Description:Inhibition of human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50062438(9-Chloro-2,2,4-trimethyl-5-m-tolyl-2,5-dihydro-1H-...)
Affinity DataKi:  0.550nMAssay Description:The binding affinity measured using baculovirus-expressed hPR-A in sf21 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50133131(9-Fluoro-2,2,4-trimethyl-5-[1-o-tolyl-meth-(Z)-yli...)
Affinity DataKi:  0.550nMAssay Description:Binding affinity towards human progesterone receptor A isoform using progesterone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50062409(5-(4-Bromo-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H-...)
Affinity DataKi:  0.550nMAssay Description:The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataKi:  0.580nMAssay Description:Binding affinity determined for human Progesterone receptor A isoformMore data for this Ligand-Target Pair
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50062442(9-Chloro-5-(4-chloro-phenyl)-2,2,4-trimethyl-2,5-d...)
Affinity DataKi:  0.590nMAssay Description:The binding affinity measured using baculovirus-expressed hPR-A in sf21 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50062445(5-(4-Bromo-phenyl)-9-chloro-2,2,4-trimethyl-2,5-di...)
Affinity DataKi:  0.590nMAssay Description:The binding affinity measured using baculovirus-expressed hPR-A in sf21 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50133135(9-Fluoro-2,2,4-trimethyl-5-[1-(2-methylsulfanyl-ph...)
Affinity DataKi:  0.590nMAssay Description:Binding affinity towards human progesterone receptor A isoform using progesterone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50133146(7-Fluoro-2,2,4-trimethyl-5-[1-phenyl-meth-(Z)-ylid...)
Affinity DataKi:  0.610nMAssay Description:Binding affinity towards human progesterone receptor A isoform using progesterone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50133139(9-Fluoro-5-[1-(2-fluoro-phenyl)-meth-(Z)-ylidene]-...)
Affinity DataKi:  0.620nMAssay Description:Binding affinity towards human progesterone receptor A isoform using progesterone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50133152(9-Fluoro-2,2,4-trimethyl-5-[1-phenyl-meth-(Z)-ylid...)
Affinity DataKi:  0.620nMAssay Description:Binding affinity towards human progesterone receptor A isoform using progesterone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataKi:  0.640nMAssay Description:Inhibition of human progesterone receptorMore data for this Ligand-Target Pair
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50067684(2,2,4-Trimethyl-5-[1-o-tolyl-meth-(Z)-ylidene]-2,5...)
Affinity DataKi:  0.660nMAssay Description:Binding affinity against human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50067684(2,2,4-Trimethyl-5-[1-o-tolyl-meth-(Z)-ylidene]-2,5...)
Affinity DataKi:  0.660nMAssay Description:Binding affinity towards human progesterone receptor A isoform using progesterone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50067684(2,2,4-Trimethyl-5-[1-o-tolyl-meth-(Z)-ylidene]-2,5...)
Affinity DataKi:  0.660nMAssay Description:Binding affinity to human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50062419(5-(3-Fluoro-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H...)
Affinity DataKi:  0.690nMAssay Description:The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50062417(5-(4-Chloro-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H...)
Affinity DataKi:  0.700nMAssay Description:The binding affinity measured using baculovirus-expressed hPR-A in sf21 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 3623 total ) | Next | Last >>
Jump to: