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Report error Found 36 Enz. Inhib. hit(s) with Target = 'Prolyl 4-hydroxylase subunit alpha-1'
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50042876(CHEMBL332005 | [2,2']Bipyridinyl-5,5'-dicarboxylic...)
Affinity DataKi:  140nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50092609(CHEMBL3586252)
Affinity DataKi:  200nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
Affinity DataKi:  540nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM26114(CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...)
Affinity DataKi:  800nMAssay Description:Inhibitory activity against prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM26114(CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...)
Affinity DataKi:  2.60E+3nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM50100861(3,4-Dihydroxybenzoate, VIII | 3,4-dihydroxybenzoic...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM92714(3,4-Dihydroxymandelate, XVI)
Affinity DataKi:  9.00E+3nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM52946(2-(3,4-dihydroxyphenyl)acetic acid | 2-[3,4-bis(ox...)
Affinity DataKi:  9.00E+3nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM41957(3-(3,4-dihydroxyphenyl)propanoic acid | 3-(3,4-dih...)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM4375((2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid | (2...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM26188(α-CA inhibitor, 12 | 1,2-Dihydroxybenzene, XI...)
Affinity DataKi:  2.50E+4nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM50085536(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)
Affinity DataKi:  3.00E+4nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM50031472(1,2,3-Trihydroxybenzene, XIV | CHEMBL307145 | Pyro...)
Affinity DataKi:  3.00E+4nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM92456(2,3-Dihydroxybenzoate, IV | 2,3-dihydroxybenzoic a...)
Affinity DataKi:  7.00E+4nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM74208(2,4-bis(oxidanyl)benzoic acid | 2,4-dihydroxybenzo...)
Affinity DataKi:  5.30E+5nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM92712(2,6-Dihydroxybenzoate, VII)
Affinity DataKi:  1.10E+6nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM50335808(2,5-Dihydroxybenzoate, VI | 2,5-dihydroxybenzoic a...)
Affinity DataKi:  1.40E+6nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM26193(2-Hydroxybenzoate, I | 2-hydroxybenzoic acid | CHE...)
Affinity DataKi:  2.30E+6nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM26194(4-Hydroxybenzoate, III | 4-hydroxybenzoic acid | C...)
Affinity DataKi:  3.20E+6nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM50336490(3,5-DIHYDROXYBENZOATE | 3,5-Dihydroxy-benzoic acid...)
Affinity DataKi:  9.00E+6nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM26189(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)
Affinity DataKi:  1.02E+7nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataKi:  1.40E+7nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM50070030(5-(1,2-Dihydroxy-ethyl)-3,4-dihydroxy-dihydro-fura...)
Affinity DataKi: >2.00E+7nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM92715((+)-Mandelate, XXI | (-)-Mandelate, XX)
Affinity DataKi: >2.00E+7nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM16419(2-phenylacetic acid | Benzeneacetic acid | CHEMBL1...)
Affinity DataKi: >2.00E+7nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM92715((+)-Mandelate, XXI | (-)-Mandelate, XX)
Affinity DataKi: >2.00E+7nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM50336491(3-Hydroxy-benzoic acid | 3-Hydroxybenzoate | 3-Hyd...)
Affinity DataKi: >2.00E+7nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50042876(CHEMBL332005 | [2,2']Bipyridinyl-5,5'-dicarboxylic...)
Affinity DataIC50:  840nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50092609(CHEMBL3586252)
Affinity DataIC50:  1.20E+3nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
Affinity DataIC50:  2.89E+3nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM26114(CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...)
Affinity DataIC50:  5.18E+3nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM26114(CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...)
Affinity DataIC50:  1.50E+4nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000866(2-(Oxalyl-amino)-propionic acid (0.25H2O) | CHEMBL...)
Affinity DataIC50:  3.82E+4nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000865(2-(Oxalyl-amino)-propionic acid | CHEMBL314979)
Affinity DataIC50:  9.07E+4nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000864(CHEMBL314175 | N-(2-Methanesulfonylamino-2-oxo-eth...)
Affinity DataIC50:  4.14E+5nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000863(2-(Oxalyl-amino)-propionic acid | CHEMBL88472)
Affinity DataIC50:  6.21E+5nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylase at 50 ug/mLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed