Compile Data Set for Download or QSAR
Report error Found 1868 Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP3 subtype'
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101825BDBM50101825((Z)-7-{(1R,2R,3R)-3-Hydroxy-2-[(E)-(S)-4-hydroxy-4...)
Affinity DataKi: >0.000100nMAssay Description:Binding affinity towards mouse Prostanoid EP3 receptor in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101827BDBM50101827((Z)-7-{(1R,2R,3R)-2-[(E)-(S)-4-(1-Ethyl-cyclobutyl...)
Affinity DataKi: >0.000100nMAssay Description:Binding affinity towards mouse Prostanoid EP3 receptor in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101826BDBM50101826((Z)-7-{(1R,2R,3R)-3-Hydroxy-2-[(E)-(S)-4-hydroxy-4...)
Affinity DataKi: >0.000100nMAssay Description:Binding affinity towards mouse Prostanoid EP3 receptor in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101823BDBM50101823(4-(2-{(1R,3R)-3-Hydroxy-2-[(E)-(S)-4-hydroxy-4-(1-...)
Affinity DataKi: >0.000100nMAssay Description:Binding affinity towards mouse Prostanoid EP3 receptor in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101833BDBM50101833((Z)-7-{(1R,2R,3R)-3-Hydroxy-2-[(E)-(S)-4-hydroxy-4...)
Affinity DataKi: >0.000100nMAssay Description:Binding affinity towards mouse Prostanoid EP3 receptor in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101832BDBM50101832((E)-7-{(1R,3R)-3-Hydroxy-2-[(E)-(S)-4-hydroxy-4-(1...)
Affinity DataKi: >0.000100nMAssay Description:Binding affinity towards mouse Prostanoid EP3 receptor in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315980BDBM50315980(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...)
Affinity DataKi:  0.0650nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317912BDBM50317912(3-[4-[(2,5-Difluorophenoxy)methyl]-2-({[(1R)-1-(3,...)
Affinity DataKi:  0.0680nMAssay Description:Displacement of [3H]PGE2 from mouse EP3alpha receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315979BDBM50315979(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...)
Affinity DataKi:  0.0860nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307436BDBM50307436(3-[4-[(2-Chlorophenoxy)methyl]-2-({[1-(3,5-dimethy...)
Affinity DataKi:  0.0900nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315482BDBM50315482(N-(3-chlorophenylsulfonyl)-3-(3,3-difluoro-1-(naph...)
Affinity DataIC50: 0.100nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307408BDBM50307408(3-[4-[(2,5-Difluorophenoxy)methyl]-2-({[1-(3,5-dim...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307434BDBM50307434(3-{2-({[1-(3,5-Dimethylphenyl)-3-methylbutyl]amino...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307441BDBM50307441(3-{2-({[1-(3,5-Dimethylphenyl)-3-methylbutyl]amino...)
Affinity DataKi:  0.110nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307406BDBM50307406(3-[4-[(3-Cyanophenoxy)methyl]-2-({[1-(3,5-dimethyl...)
Affinity DataKi:  0.120nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315985BDBM50315985(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(methyl(phenyl...)
Affinity DataKi:  0.120nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307414BDBM50307414(3-[2-({[1-(3-Methoxyphenyl)-3-methylbutyl]amino}ca...)
Affinity DataKi:  0.130nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307445BDBM50307445(3-[4-[(3-Cyanophenoxy)methyl]-2-({[1-(3-methoxyphe...)
Affinity DataKi:  0.130nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315981BDBM50315981(3-(4-((1H-pyrazol-1-yl)methyl)-2-(naphthalen-1-ylm...)
Affinity DataKi:  0.130nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307405BDBM50307405(3-{2-({[1-(3,5-Dimethylphenyl)-3-methylbutyl]amino...)
Affinity DataKi:  0.130nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307428BDBM50307428(3-[2-({[1-(3-Fluoro-4-methoxyphenyl)-3-methylbutyl...)
Affinity DataKi:  0.140nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85177BDBM85177(CAS_80558-61-8 | NSC_119139 | M&B-28767)
Affinity DataKi:  0.140nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307449BDBM50307449(3-[4-[(2,3-Difluorophenoxy)methyl]-2-({[1-(3,5-dim...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317907BDBM50317907(3-[4-[(3-Chlorophenoxy)methyl]-2-({[(1R)-1-(3,5-di...)
Affinity DataKi:  0.160nMAssay Description:Displacement of [3H]PGE2 from mouse EP3alpha receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307403BDBM50307403(3-[2-({[1-(4-Fluoro-3-methylphenyl)-3-methylbutyl]...)
Affinity DataKi:  0.160nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307424BDBM50307424(3-[2-({[1-(4-Methoxy-3-methylphenyl)-3-methylbutyl...)
Affinity DataKi:  0.160nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315967BDBM50315967(N-(3,4-difluorophenylsulfonyl)-3-(2-(2-(naphthalen...)
Affinity DataKi:  0.160nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307423BDBM50307423(3-[2-({[1-(3,4-Dimethylphenyl)-3-methylbutyl]amino...)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307446BDBM50307446(3-[4-[(3-Cyanophenoxy)methyl]-2-({[1-(4-fluorophen...)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307407BDBM50307407(3-{2-({[1-(3,5-Dimethylphenyl)-3-methylbutyl]amino...)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307419BDBM50307419(3-[2-({[1-(3-Chlorophenyl)-3-methylbutyl]amino}car...)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307450BDBM50307450(3-[4-[(2,4-Difluorophenoxy)methyl]-2-({[1-(3,5-dim...)
Affinity DataKi:  0.190nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317908BDBM50317908(3-{2-({[(1R)-1-(3,5-Dimethylphenyl)-3-methylbutyl]...)
Affinity DataKi:  0.190nMAssay Description:Displacement of [3H]PGE2 from mouse EP3alpha receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307453BDBM50307453(3-[4-[(3,5-Difluorophenoxy)methyl]-2-({[1-(3,5-dim...)
Affinity DataKi:  0.190nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307404BDBM50307404(3-[2-({[1-(3,5-Dimethylphenyl)-3-methylbutyl]amino...)
Affinity DataKi:  0.190nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307417BDBM50307417(3-[2-({[1-(3-Fluorophenyl)-3-methylbutyl]amino}car...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307444BDBM50307444(3-[4-[(3-Cyanophenoxy)methyl]-2-({[3-methyl-1-(3-m...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315474BDBM50315474(N-(3-chlorophenylsulfonyl)-3-(1-(2,4-dichlorobenzy...)
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315473BDBM50315473(3-(1-(2,4-dichlorobenzyl)-3,3-difluoro-2-oxoindoli...)
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315472BDBM50315472(3-(1-(2,4-dichlorobenzyl)-3,3-difluoro-2-oxoindoli...)
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315471BDBM50315471(3-(1-(2,4-dichlorobenzyl)-3,3-difluoro-2-oxoindoli...)
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315476BDBM50315476(3-(1-(2,4-dichlorobenzyl)-3,3-difluoro-2-oxoindoli...)
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307447BDBM50307447(3-[4-[(3-Cyanophenoxy)methyl]-2-({[1-(4-fluoro-3-m...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315480BDBM50315480(3-(3,3-difluoro-1-(naphthalen-2-ylmethyl)-2-oxoind...)
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254766BDBM50254766(2-(3-(2,4-dichlorophenylthio)-1H-indol-4-yloxy)-N-...)
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315982BDBM50315982(3-(4-((1H-pyrazol-1-yl)methyl)-2-phenethoxyphenyl)...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307427BDBM50307427(3-[2-({[1-(3-Fluoro-4-methylphenyl)-3-methylbutyl]...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315493BDBM50315493(3-(1-(2,4-dichlorobenzyl)-2-oxoindolin-7-yl)-N-(2,...)
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307437BDBM50307437(3-[4-[(3-Chlorophenoxy)methyl]-2-({[1-(3,5-dimethy...)
Affinity DataKi:  0.210nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308906BDBM50308906(3-[2-({[(1R)-1-(1-Naphthyl)ethyl]amino}carbonyl)-4...)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]PGE3alpha from mouse EP3alpha receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
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