Report error Found 9974 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2'
Affinity DataKd: 160nMpH: 8.0Assay Description:POX reactions were conducted in 2 ml of filtered and degassed 50 mM Tris-HCl, pH 8.0, containing 50 mM NaCl, 0.1 mM H2O2, 4.5 mM guaiacol, and the in...More data for this Ligand-Target Pair
Affinity DataKd: 370nMpH: 8.0Assay Description:POX reactions were conducted in 2 ml of filtered and degassed 50 mM Tris-HCl, pH 8.0, containing 50 mM NaCl, 0.1 mM H2O2, 4.5 mM guaiacol, and the in...More data for this Ligand-Target Pair
Affinity DataKd: 620nMpH: 8.0Assay Description:POX reactions were conducted in 2 ml of filtered and degassed 50 mM Tris-HCl, pH 8.0, containing 50 mM NaCl, 0.1 mM H2O2, 4.5 mM guaiacol, and the in...More data for this Ligand-Target Pair
Affinity DataKd: 240nMpH: 8.0Assay Description:POX reactions were conducted in 2 ml of filtered and degassed 50 mM Tris-HCl, pH 8.0, containing 50 mM NaCl, 0.1 mM H2O2, 4.5 mM guaiacol, and the in...More data for this Ligand-Target Pair
Affinity DataKd: 8.07E+3nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
Affinity DataKd: 230nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
Affinity DataKd: 51.3nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
Affinity DataKd: 203nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
Affinity DataKd: 51.1nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
Affinity DataKd: 40.8nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
Affinity DataKd: 14.0nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
Affinity DataKd: 56.4nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
Affinity DataKd: 3.30nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
Affinity DataKd: 3.30nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
Affinity DataKd: 1.02E+3nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
Affinity DataKd: 789nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
Affinity DataKd: 652nMAssay Description:Binding affinity to COX2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 448nMAssay Description:Binding affinity to COX2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 227nMAssay Description:Binding affinity to COX2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 92nMAssay Description:Binding affinity to COX2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 50nMAssay Description:Binding affinity to COX2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 48nMAssay Description:Binding affinity to COX2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at human recombinant COX2 using arachidonic acid as substrate measured after 5 mins by ADHP reagent based fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Binding affinity to human COX2More data for this Ligand-Target Pair
Affinity DataKd: 0.190nMAssay Description:Binding affinity to COX2 by surface plasmon resonance spectroscopyMore data for this Ligand-Target Pair
Affinity DataEC50: 330nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.00603nMAssay Description:Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophageMore data for this Ligand-Target Pair
Affinity DataIC50: 0.00600nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.00600nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophageMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophageMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophageMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
Affinity DataIC50: 0.0692nMAssay Description:Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophageMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Tested in vitro for inhibition against Prostaglandin G/H synthase 2 in human blood (95% confidence limits)More data for this Ligand-Target Pair
Affinity DataIC50: 0.0891nMAssay Description:Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophageMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0891nMAssay Description:Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophageMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Tested in vitro for inhibition against Prostaglandin G/H synthase 2 in human blood (95% confidence limits)More data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition by colorimetric assa...More data for this Ligand-Target Pair
Affinity DataIC50: 0.141nMAssay Description:Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophageMore data for this Ligand-Target Pair
Affinity DataIC50: 0.170nMAssay Description:Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophageMore data for this Ligand-Target Pair
Affinity DataIC50: 0.178nMAssay Description:Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophageMore data for this Ligand-Target Pair
