Compile Data Set for Download or QSAR
Found 1708 Enz. Inhib. hit(s) with Target = 'Protease'
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM4685((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.0000150nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM577((3S)-oxolan-3-yl N-[(2S,3R)-4-[(4-aminobenzene)(2-...)
Affinity DataKi:  0.0000570nMAssay Description:Inhibition of HIV1 protease by fluorescent peptide substrate based assayMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM8125((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.000200nMAssay Description:Inhibition of wild type HIV1 protease by FRET assayMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM12877((5S)-3-(3-Acetylphenyl)-N-[(1S,2R)-1-benzyl-2-hydr...)
Affinity DataKi:  0.000800nMAssay Description:Inhibition of wild type HIV1 protease by FRETMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM12877((5S)-3-(3-Acetylphenyl)-N-[(1S,2R)-1-benzyl-2-hydr...)
Affinity DataKi:  0.00100nMAssay Description:Inhibition of wild type HIV1 protease by FRET assayMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50505279(CHEMBL4436207)
Affinity DataKi:  0.00100nMAssay Description:Inhibition of HIV1 protease using RE(Edans)SGIFLETSK(Dabcyl)R as substrate by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50485746(CHEMBL2165886)
Affinity DataKi:  0.00100nMAssay Description:Inhibition of wild type HIV1 protease by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50469417(CHEMBL4293023)
Affinity DataKi:  0.00120nMAssay Description:Inhibition of HIV1 wild type NL4-3 protease expressed in Escherichia coli Rosetta (DE3) pLysS using Abz-Thr-Ile-Nle-Phe-(pNO2)-Gln-Arg-NH2 as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM8125((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.00147nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50498523(CHEMBL3605643)
Affinity DataKi:  0.00150nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50484842(CHEMBL1958482 | GRL-0249A)
Affinity DataKi:  0.00180nMAssay Description:Inhibition of HIV1 protease using hexapeptide Ac-Thr-Ile-Nle-Nle-Gln-Arg-NH2 as substrate by fluorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50528147(CHEMBL4514504)
Affinity DataKi:  0.00200nMAssay Description:Inhibition of HIV-1 proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50528152(CHEMBL4532946)
Affinity DataKi:  0.00200nMAssay Description:Inhibition of HIV-1 proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50457611(CHEMBL4214453)
Affinity DataKi:  0.00200nMAssay Description:Inhibition of wild type HIV-1 NL4-3 protease expressed in Escherichia coli Rosetta (DE3)pLysS using Ac-Thr-Ile-Nle-Nle-Gln-Arg-NH2 as substrate by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50480930(CHEMBL584130 | KNI-814)
Affinity DataKi:  0.00240nMAssay Description:Inhibition of HIV1 recombinant protease after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50483336(CHEMBL1651153 | GRL-0476)
Affinity DataKi:  0.00270nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50485740(CHEMBL2165903)
Affinity DataKi:  0.00300nMAssay Description:Inhibition of wild type HIV1 protease by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50498230(CHEMBL3577576)
Affinity DataKi:  0.00300nMAssay Description:Inhibition of wild type HIV1 proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50485764(CHEMBL2165912)
Affinity DataKi:  0.00300nMAssay Description:Inhibition of wild type HIV1 protease by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50485744(CHEMBL2165917)
Affinity DataKi:  0.00300nMAssay Description:Inhibition of wild type HIV1 protease by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50483092(CHEMBL1276087)
Affinity DataKi:  0.00300nMAssay Description:Inhibition of wild type HIV1 protease by FRETMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM13925((3aS,5R,6aR)-hexahydro-2H-cyclopenta[b]furan-5-yl ...)
Affinity DataKi:  0.00350nMAssay Description:Inhibition of HIV1 protease dimerization in MT2 cellsMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50498524(CHEMBL3605638)
Affinity DataKi:  0.00390nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50484847(CHEMBL1958483 | GRL-0289A)
Affinity DataKi:  0.00400nMAssay Description:Inhibition of HIV1 protease using hexapeptide Ac-Thr-Ile-Nle-Nle-Gln-Arg-NH2 as substrate by fluorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50485747(CHEMBL2165900)
Affinity DataKi:  0.00500nMAssay Description:Inhibition of wild type HIV1 protease by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50485760(CHEMBL2165901)
Affinity DataKi:  0.00500nMAssay Description:Inhibition of wild type HIV1 protease by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50484190(CHEMBL1817686)
Affinity DataKi:  0.00500nMAssay Description:Inhibition of Human immunodeficiency virus 1 protease assessed as release of fluorescent N-terminal tripeptide using fluorogenic substrate by continu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50180655(A-157378-0 | A-157378.0 | ABT-378 | CHEBI:31781 | ...)
Affinity DataKi:  0.00500nMAssay Description:Inhibition of wild type HIV1 protease by FRETMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM13925((3aS,5R,6aR)-hexahydro-2H-cyclopenta[b]furan-5-yl ...)
Affinity DataKi:  0.00500nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM8125((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.00500nMAssay Description:Inhibition of wild type HIV1 proteaseMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50457604(CHEMBL4213229)
Affinity DataKi:  0.00500nMAssay Description:Inhibition of wild type HIV-1 NL4-3 protease expressed in Escherichia coli Rosetta (DE3)pLysS using Ac-Thr-Ile-Nle-Nle-Gln-Arg-NH2 as substrate by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM112661((3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl ((2S,3...)
Affinity DataKi:  0.00500nMAssay Description:Inhibition of HIV1 NL4-3 protease I84V mutant expressed in Escherichia coli TAP-106 cells using EDANS/DABCYL-labelled 10-amino acid containing natura...More data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50483338(CHEMBL1651155)
Affinity DataKi:  0.00500nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50180655(A-157378-0 | A-157378.0 | ABT-378 | CHEBI:31781 | ...)
Affinity DataKi:  0.00500nMAssay Description:Binding affinity to wild type HIV1 proteaseMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50481584(CHEMBL589988 | GRL-0355)
Affinity DataKi:  0.00520nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM8125((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.00530nMAssay Description:Inhibition of wild-type HIV1 BH10 protease expressed in Escherichia coli by spectrophotometric assayMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50484191(CHEMBL1819295)
Affinity DataKi:  0.00600nMAssay Description:Inhibition of Human immunodeficiency virus 1 protease assessed as release of fluorescent N-terminal tripeptide using fluorogenic substrate by continu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50484193(CHEMBL1819294)
Affinity DataKi:  0.00600nMAssay Description:Inhibition of Human immunodeficiency virus 1 protease assessed as release of fluorescent N-terminal tripeptide using fluorogenic substrate by continu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM12883((5S)-3-(3-Acetylphenyl)-N-[(1S,2R)-3-[[(benzo[1,3]...)
Affinity DataKi:  0.00600nMAssay Description:Inhibition of wild type HIV1 protease by FRETMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50498229(CHEMBL3577575)
Affinity DataKi:  0.00600nMAssay Description:Inhibition of wild type HIV1 proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50489369(CHEMBL1232930 | GRL-0519)
Affinity DataKi:  0.00600nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50483116(CHEMBL1276096)
Affinity DataKi:  0.00600nMAssay Description:Inhibition of wild type HIV1 protease by FRETMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50528144(CHEMBL4435411)
Affinity DataKi:  0.00600nMAssay Description:Inhibition of HIV-1 proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50498534(CHEMBL3605635)
Affinity DataKi:  0.00630nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM4685((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.00680nMAssay Description:Inhibition of HIV1 protease dimerization in MT2 cellsMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM577((3S)-oxolan-3-yl N-[(2S,3R)-4-[(4-aminobenzene)(2-...)
Affinity DataKi:  0.00700nMAssay Description:Inhibition of wild type HIV1 protease by FRET assayMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50528145(CHEMBL4586218)
Affinity DataKi:  0.00700nMAssay Description:Inhibition of HIV-1 proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50484845(CHEMBL1958480)
Affinity DataKi:  0.00740nMAssay Description:Inhibition of HIV1 protease using hexapeptide Ac-Thr-Ile-Nle-Nle-Gln-Arg-NH2 as substrate by fluorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50484841(CHEMBL1958481)
Affinity DataKi:  0.00750nMAssay Description:Inhibition of HIV1 protease using hexapeptide Ac-Thr-Ile-Nle-Nle-Gln-Arg-NH2 as substrate by fluorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM8125((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.00800nMAssay Description:Inhibition of wild type HIV1 protease by FRETMore data for this Ligand-Target Pair
Displayed 1 to 50 (of 1708 total ) | Next | Last >>
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