Report error Found 845 Enz. Inhib. hit(s) with Target = 'Protein-glutamine gamma-glutamyltransferase 2'
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity to TG2 (unknown origin) assessed as dissociation constant at 30 degree C by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKd: 6.89E+4nMAssay Description:Binding affinity to TG2 (unknown origin) assessed as dissociation constant at 30 degree C by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKd: 7.80E+3nMAssay Description:Binding affinity to TG2 (unknown origin) assessed as dissociation constant at 30 degree C by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 2.10nMAssay Description:For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human TG2 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.29nMAssay Description:For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...More data for this Ligand-Target Pair
Affinity DataIC50: 6.65nMAssay Description:For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...More data for this Ligand-Target Pair
Affinity DataIC50: 8.75nMAssay Description:For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...More data for this Ligand-Target Pair
Affinity DataIC50: 9.60nMAssay Description:Inhibition of transglutaminase 2 (unknown origin)More data for this Ligand-Target Pair
TargetProtein-glutamine gamma-glutamyltransferase 2/Tyrosine-protein kinase JAK3(Human)
Duke University Medical Center
Duke University Medical Center
Affinity DataIC50: 10nMT: 2°CAssay Description:In order to eliminated fluorescence interference, chemicals were subjected to a secondary screening using colorimetric BP incorporation assay. TGase...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant TG2 by fluorescent transamidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of TG2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:2 ul of a solution of different concentrations of the test compound in dimethyl sulfoxide was added to 28 ul of buffer (50 mM TRIS, 100 mM NaCl, 10 m...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant TG2 by fluorescent transamidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Irreversible inhibition of transglutaminase 2More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant TG2 by fluorescent transamidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of mouse recombinant TG2 by fluorescent transamidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human TGase2More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant TG2 by fluorescent transamidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human TG2 using glycine methyl ester/Abz-APE as substrate after 5 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant TG2 by fluorescent transamidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant TG2 by fluorescent transamidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant TG2 by fluorescent transamidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant TG2 by fluorescent transamidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human TGase2More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human TG2 using glycine methyl ester/Abz-APE as substrate after 5 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant TG2 by fluorescent transamidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of human recombinant TG2 by fluorescent transamidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant TG2 by fluorescent transamidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of human recombinant TG2 by fluorescent transamidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant TG2 by fluorescent transamidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant TG2 by fluorescent transamidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMpH: 7.5 T: 2°CAssay Description:2 ul of a solution of different concentrations of the test compound in dimethyl sulfoxide was added to 28 ul of buffer (50 mM TRIS, 100 mM NaCl, 10 m...More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of human TG2 using glycine methyl ester/Abz-APE as substrate after 5 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
