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Report error Found 2632 Enz. Inhib. hit(s) with Target = 'RNA-directed RNA polymerase'
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50495952(CHEMBL3121489)
Affinity DataKi:  130nMAssay Description:Inhibition of HCV RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepacivirus C)
Pharmasset

Curated by ChEMBL
LigandPNGBDBM50480722(CHEMBL373691)
Affinity DataKi:  310nMAssay Description:Inhibition of HCV NS5B polymerase S282T mutant assessed as incorporation of [alpha32P]UTP into newly synthesized RNA by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)
Affinity DataKi:  420nMAssay Description:Inhibition of Hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase L(Human respiratory syncytial virus)
Georgia State University Research Foundation

US Patent
LigandPNGBDBM681988(US12016863, ZD-3-067)
Affinity DataKi:  1.60E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRNA-directed RNA polymerase L(Human respiratory syncytial virus)
Georgia State University Research Foundation

US Patent
LigandPNGBDBM681987(US12016863, GRP-268365)
Affinity DataKi:  2.20E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRNA-directed RNA polymerase L(Human respiratory syncytial virus)
Georgia State University Research Foundation

US Patent
LigandPNGBDBM681994(US12016863, GRP-171194)
Affinity DataKi:  2.40E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRNA-directed RNA polymerase L(Human respiratory syncytial virus)
Georgia State University Research Foundation

US Patent
LigandPNGBDBM33456((4-methyl-2-oxidanylidene-chromen-7-yl) ethanoate ...)
Affinity DataKi:  2.90E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In DepthDetails US Patent


TargetRNA-directed RNA polymerase L(Human respiratory syncytial virus)
Georgia State University Research Foundation

US Patent
LigandPNGBDBM681995(US12016863, RJW-3-024)
Affinity DataKi:  1.00E+4nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRNA-directed RNA polymerase(Hepacivirus C)
Pharmasset

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)
Affinity DataKi:  2.20E+4nMAssay Description:Inhibition of HCV NS5B polymerase S282T mutant assessed as incorporation of [alpha32P]UTP into newly synthesized RNA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50410390(CHEMBL1161754)
Affinity DataKi:  2.01E+5nMAssay Description:Inhibition constant against ATP binding towards Hepatitis C Virus NS5BRdRpMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50410391(CHEMBL1161753)
Affinity DataKi:  2.29E+5nMAssay Description:Inhibition constant against ATP binding towards Hepatitis C Virus NS5BRdRpMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase L(Human respiratory syncytial virus)
Georgia State University Research Foundation

US Patent
LigandPNGBDBM50305318(3-Chloro-4-methyl-7-hydroxy-2H-2-chromenone | 3-ch...)
Affinity DataKi: >3.00E+5nMAssay Description:TBDMore data for this Ligand-Target Pair
In DepthDetails US Patent


TargetRNA-directed RNA polymerase L(Human respiratory syncytial virus)
Georgia State University Research Foundation

US Patent
LigandPNGBDBM681991(US12016863, EJ3063)
Affinity DataKi: >3.00E+5nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRNA-directed RNA polymerase L(Human respiratory syncytial virus)
Georgia State University Research Foundation

US Patent
LigandPNGBDBM681990(US12016863, EJ3066)
Affinity DataKi: >3.00E+5nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRNA-directed RNA polymerase L(Human respiratory syncytial virus)
Georgia State University Research Foundation

US Patent
LigandPNGBDBM681992(US12016863, EJ3061)
Affinity DataKi: >3.00E+5nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRNA-directed RNA polymerase L(Human respiratory syncytial virus)
Georgia State University Research Foundation

US Patent
LigandPNGBDBM681996(US12016863, ZD-3-069)
Affinity DataKi: >3.00E+5nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRNA-directed RNA polymerase L(Human respiratory syncytial virus)
Georgia State University Research Foundation

US Patent
LigandPNGBDBM681997(US12016863, ZD-3-064)
Affinity DataKi: >3.00E+5nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRNA-directed RNA polymerase L(Human respiratory syncytial virus)
Georgia State University Research Foundation

US Patent
LigandPNGBDBM681998(US12016863, EJ3062)
Affinity DataKi: >3.00E+5nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRNA-directed RNA polymerase L(Human respiratory syncytial virus)
Georgia State University Research Foundation

US Patent
LigandPNGBDBM681999(US12016863, EJ3051)
Affinity DataKi: >3.00E+5nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRNA-directed RNA polymerase L(Human respiratory syncytial virus)
Georgia State University Research Foundation

US Patent
LigandPNGBDBM682000(US12016863, EJ3043)
Affinity DataKi: >3.00E+5nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRNA-directed RNA polymerase L(Human respiratory syncytial virus)
Georgia State University Research Foundation

US Patent
LigandPNGBDBM682001(US12016863, EJ3057)
Affinity DataKi: >3.00E+5nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRNA-directed RNA polymerase L(Human respiratory syncytial virus)
Georgia State University Research Foundation

US Patent
LigandPNGBDBM682002(US12016863, EJ3054)
Affinity DataKi: >3.00E+5nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50410392(CHEMBL1161773)
Affinity DataKi:  3.27E+5nMAssay Description:Inhibition constant against ATP binding towards Hepatitis C Virus NS5BRdRpMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50462413(CHEMBL4248257)
Affinity DataIC50:  0.00100nMAssay Description:Inhibition of HCV NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50186156(CHEMBL379613 | N-{3-[1-(cyclobutylamino)-4-hydroxy...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of HCV 1b NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50162106(1-Cyclohexyl-2-(2-fluoro-4-hydroxy-phenyl)-1H-benz...)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory concentration against RNA dependent RNA polymerase nonstructural protein 5B of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50181954((S)-5-tert-butyl-1-(3,3-dimethyl-butyl)-3-(1,1-dio...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of HCV NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50186153(CHEMBL210158 | N-{3-[4-Hydroxy-1-(3-methyl-butyl)-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of HCV 1a NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50186153(CHEMBL210158 | N-{3-[4-Hydroxy-1-(3-methyl-butyl)-...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of HCV 1a NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50186150(CHEMBL208740 | N-{3-[4-hydroxy-1-(3-methylbutyl)-2...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of HCV 1b NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50186184(CHEMBL211336 | propane-2-sulfonic acid {3-[4-hydro...)
Affinity DataIC50:  3nMAssay Description:Inhibition of HCV 1b NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50162110(1-Cyclohexyl-2-(4-hydroxy-phenyl)-1H-benzoimidazol...)
Affinity DataIC50:  3nMAssay Description:Inhibitory concentration against RNA dependent RNA polymerase nonstructural protein 5B of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50218786(2-(4-(2-(2-cyclopentyl-5-((5,7-dimethyl-[1,2,4]tri...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50162109(3-Cyclohexyl-2-(4-hydroxy-phenyl)-1H-indole-6-carb...)
Affinity DataIC50:  4.80nMAssay Description:Inhibitory concentration against RNA dependent RNA polymerase nonstructural protein 5B of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50537585(CHEMBL4646449)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against HIV-1 Y181C reverse transcriptase.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50186206(Bbutane-1-sulfonic acid {3-[4-hydroxy-1-(3-methyl-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of HCV 1b NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50293134(2-[4-(2-{2-cyclopentyl-5-[(5,7-dimethyl[1,2,4]tria...)
Affinity DataIC50:  5nMAssay Description:Inhibition of Hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50186156(CHEMBL379613 | N-{3-[1-(cyclobutylamino)-4-hydroxy...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of HCV 1a NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50186147(CHEMBL210050 | N-benzyl({3-[4-hydroxy-1-(3-methylb...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of HCV 1a NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50186153(CHEMBL210158 | N-{3-[4-Hydroxy-1-(3-methyl-butyl)-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of HCV 1b NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM100761(US8507683, 12)
Affinity DataIC50:  6nMAssay Description:HCV NS5B enzyme assay.More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50162099(2-(4-Benzyloxy-phenyl)-3-cyclohexyl-1-dimethylcarb...)
Affinity DataIC50:  6nMAssay Description:Inhibitory activity against RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50158838(2-{4-[2-(4-chlorophenyl)-5-(4-hydroxyhexahydro-1-p...)
Affinity DataIC50: <6nMAssay Description:Inhibitory concentration against RNA dependent RNA polymerase nonstructural protein 5B of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50537587(CHEMBL4633142)
Affinity DataIC50:  6nMAssay Description:Inhibitory activity against HIV-1 Y181C reverse transcriptase.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50186153(CHEMBL210158 | N-{3-[4-Hydroxy-1-(3-methyl-butyl)-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of HCV 1b NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50186141(2-cyanoethyl N-({3-[4-hydroxy-1-(3-methylbutyl)-2-...)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of HCV 1b NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50186185(CHEMBL211408 | N-{3-[4-hydroxy-1-(3-methyl-butyl)-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of HCV 1b NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50169942(2-(4-Chloro-phenyl)-3-cyclohexyl-1-[2-(4-methanesu...)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50293131((6R)-6-cyclopentyl-6-[2-(2,6-diethylpyridin-4-yl)e...)
Affinity DataIC50:  7nMAssay Description:Inhibition of Hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50186184(CHEMBL211336 | propane-2-sulfonic acid {3-[4-hydro...)
Affinity DataIC50:  8nMAssay Description:Inhibition of HCV 1a NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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