Compile Data Set for Download or QSAR
Report error Found 3994 Enz. Inhib. hit(s) with Target = 'Reverse transcriptase/RNaseH'
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50366817(Epivir)
Affinity DataEC50:  42nMAssay Description:In vitro antiviral activity against HIV-1 Reverse transcriptase wild typeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50421604(ACH-126443 | ELVUCITABINE)
Affinity DataEC50:  180nMAssay Description:In vitro antiviral activity against HIV-1 Reverse transcriptase wild typeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50279762(9-Chloro-5-methyl-6-(3-methyl-but-2-enyl)-1,5,6,7-...)
Affinity DataEC50:  60nMAssay Description:Effective concentration required against wild type HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM2337(CHEMBL35033 | 6-benzyl-1-(ethoxymethyl)-5-(propan-...)
Affinity DataEC50:  20nMAssay Description:Effective concentration required against L100I mutant HIV-1 reverse transcriptase (as per ref 7 in the article)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataEC50:  30nMAssay Description:Effective concentration required against wild type HIV-1 reverse transcriptase (as per ref 8 in the article)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50105629(UC-781 | N-{4-chloro-3-[(3-methylbut-2-enyl)oxy]ph...)
Affinity DataEC50:  9nMAssay Description:Effective concentration required against wild type HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50138403([(2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-2,5-d...)
Affinity DataKd:  1.80E+4nMAssay Description:Equilibrium binding constant at the active site of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50138406([(2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-o...)
Affinity DataKd:  1.50E+4nMAssay Description:Equilibrium binding constant at the active site of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50138405([(2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-...)
Affinity DataKd:  1.20E+4nMAssay Description:Equilibrium binding constant at the active site of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50138404([(2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-...)
Affinity DataKd:  6.40E+4nMAssay Description:Equilibrium binding constant at the active site of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50138402([(2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-...)
Affinity DataKd:  3.10E+4nMAssay Description:Equilibrium binding constant at the active site of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50057812(1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-...)
Affinity DataEC50:  1.30E+4nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50057803(1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-...)
Affinity DataEC50:  1.30E+3nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50057809(3-Amino-1-(4-azido-5-hydroxymethyl-tetrahydro-fura...)
Affinity DataEC50:  500nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50057819(1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-...)
Affinity DataEC50:  1.50E+3nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50057821([3-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)...)
Affinity DataEC50:  4.70E+3nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50002692(1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...)
Affinity DataEC50:  3nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50057804(1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-...)
Affinity DataEC50: >2.90E+4nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50057814(2-{2-[3-(4-Azido-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataEC50:  1.14E+5nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50057818(1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-...)
Affinity DataEC50:  120nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50057808(1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-...)
Affinity DataEC50:  1.43E+5nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50057805(1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-...)
Affinity DataEC50:  100nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50057810(1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-...)
Affinity DataEC50:  90nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50057822(1-(4-azido-5-hydroxymethyltetrahydro-2-furanyl)-3-...)
Affinity DataEC50:  1.40E+3nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50057807([3-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)...)
Affinity DataEC50:  1.40E+4nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50057811(1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-...)
Affinity DataEC50:  1.20E+3nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50057823(3-Allyl-1-(4-azido-5-hydroxymethyl-tetrahydro-fura...)
Affinity DataEC50:  6.50E+4nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50057815(1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-...)
Affinity DataEC50:  1.40E+5nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50057816(3-(2-Azido-ethyl)-1-(4-azido-5-hydroxymethyl-tetra...)
Affinity DataEC50:  1.50E+3nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM17666(CHEMBL58581 | 2-(2,6-difluorophenyl)-1-[(2,6-diflu...)
Affinity DataEC50:  1.29E+4nMAssay Description:Cross Resistance (antiviral activity) with K103N (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM17665(CHEMBL293961 | 2-(2,6-difluorophenyl)-1-[(2,6-difl...)
Affinity DataEC50:  1.40E+3nMAssay Description:Cross Resistance (antiviral activity) with A98G (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM10245(3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....)
Affinity DataEC50: >2.00E+4nMAssay Description:Cross Resistance (antiviral activity) with K101E (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM17666(CHEMBL58581 | 2-(2,6-difluorophenyl)-1-[(2,6-diflu...)
Affinity DataEC50:  460nMAssay Description:Cross Resistance (antiviral activity) with L74V (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50036504((S-(+))-8-Methyl-6,7,8,9-tetrahydro-2H-2,7,9a-tria...)
Affinity DataEC50:  200nMAssay Description:Cross Resistance (antiviral activity) with L74V (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM10245(3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....)
Affinity DataEC50:  1.63E+4nMAssay Description:Cross Resistance (antiviral activity) with Y181C (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM17665(CHEMBL293961 | 2-(2,6-difluorophenyl)-1-[(2,6-difl...)
Affinity DataEC50:  2.30E+3nMAssay Description:Cross Resistance (antiviral activity) with Y188C (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM17666(CHEMBL58581 | 2-(2,6-difluorophenyl)-1-[(2,6-diflu...)
Affinity DataEC50: >2.00E+4nMAssay Description:Cross Resistance (antiviral activity) with V106A (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50036504((S-(+))-8-Methyl-6,7,8,9-tetrahydro-2H-2,7,9a-tria...)
Affinity DataEC50:  1.25E+4nMAssay Description:Cross Resistance (antiviral activity) with V106A (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM17666(CHEMBL58581 | 2-(2,6-difluorophenyl)-1-[(2,6-diflu...)
Affinity DataEC50:  1.85E+3nMAssay Description:Cross Resistance (antiviral activity) with NL4-3(WT) NNRTI (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM17665(CHEMBL293961 | 2-(2,6-difluorophenyl)-1-[(2,6-difl...)
Affinity DataEC50:  300nMAssay Description:Cross Resistance (antiviral activity) with L100I (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM10245(3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....)
Affinity DataEC50:  9.70E+3nMAssay Description:Cross Resistance (antiviral activity) with V108I (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM10245(3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....)
Affinity DataEC50:  1.22E+4nMAssay Description:Cross Resistance (antiviral activity) with L100I (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50036504((S-(+))-8-Methyl-6,7,8,9-tetrahydro-2H-2,7,9a-tria...)
Affinity DataEC50: >1.74E+4nMAssay Description:Cross Resistance (antiviral activity) with 4xAZT/L100I (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM17665(CHEMBL293961 | 2-(2,6-difluorophenyl)-1-[(2,6-difl...)
Affinity DataEC50:  100nMAssay Description:Cross Resistance (antiviral activity) with L74V (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM10245(3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....)
Affinity DataEC50:  700nMAssay Description:Cross Resistance (antiviral activity) with L74V (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM17666(CHEMBL58581 | 2-(2,6-difluorophenyl)-1-[(2,6-diflu...)
Affinity DataEC50:  1.04E+4nMAssay Description:Cross Resistance (antiviral activity) with V108I (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM17665(CHEMBL293961 | 2-(2,6-difluorophenyl)-1-[(2,6-difl...)
Affinity DataEC50:  2.00E+4nMAssay Description:Cross Resistance (antiviral activity) with V106A (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM17665(CHEMBL293961 | 2-(2,6-difluorophenyl)-1-[(2,6-difl...)
Affinity DataEC50:  2.80E+3nMAssay Description:Cross Resistance (antiviral activity) with V108I (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate vMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM17666(CHEMBL58581 | 2-(2,6-difluorophenyl)-1-[(2,6-diflu...)
Affinity DataEC50:  1.52E+4nMAssay Description:Cross Resistance (antiviral activity) with Y181C (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM17665(CHEMBL293961 | 2-(2,6-difluorophenyl)-1-[(2,6-difl...)
Affinity DataEC50:  1.67E+4nMAssay Description:Cross Resistance (antiviral activity) with K101E (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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