Report error Found 541 Enz. Inhib. hit(s) with Target = 'Sphingosine kinase 2'
Affinity DataKi: 0.0900nMAssay Description:Inhibition of recombinant human Sphk2 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m...More data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Inhibition of recombinant human Sphk2 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m...More data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Inhibition of recombinant human Sphk2 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of recombinant human Sphk2 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m...More data for this Ligand-Target Pair
Affinity DataKi: 0.980nMAssay Description:Inhibition of recombinant human Sphk2 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of recombinant human Sphk2 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m...More data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Inhibition of SK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 89nMAssay Description:Inhibition of recombinant human SphK2 assessed as decrease in [33P]SIP production using sphingosine as substrate in presence of [gamma33P]-ATP by sci...More data for this Ligand-Target Pair
Affinity DataKi: 89nMAssay Description:Inhibition of recombinant human SphK2 expressed in baculovirus infected Sf9 cells assessed as decrease in [33P]S1P production using varying level of ...More data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Inhibition of recombinant human SPHK2 at using sphingosine as substrate after 30 mins in presence of gamma-[32P]-ATP by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Inhibition of recombinant human SPHK2 at using sphingosine as substrate after 30 mins in presence of gamma-[32P]-ATP by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Inhibition of recombinant human SPHK2 at using sphingosine as substrate after 30 mins in presence of gamma-[32P]-ATP by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Inhibition of recombinant human SPHK2 at using sphingosine as substrate after 30 mins in presence of gamma-[32P]-ATP by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 186nMAssay Description:Inhibition of recombinant human SphK2 expressed in baculovirus infected Sf9 cells assessed as decrease in [33P]S1P production using varying level of ...More data for this Ligand-Target Pair
Affinity DataKi: 192nMAssay Description:Inhibition of recombinant human SphK2 expressed in baculovirus infected Sf9 cells assessed as decrease in [33P]S1P production using varying level of ...More data for this Ligand-Target Pair
Affinity DataKi: 197nMAssay Description:Inhibition of recombinant human SphK2 expressed in baculovirus infected Sf9 cells assessed as decrease in [33P]S1P production using varying level of ...More data for this Ligand-Target Pair
Affinity DataKi: 201nMAssay Description:Inhibition of recombinant human SphK2 expressed in baculovirus infected Sf9 cells assessed as decrease in [33P]S1P production using varying level of ...More data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Inhibition of recombinant human SPHK2 at using sphingosine as substrate after 30 mins in presence of gamma-[32P]-ATP by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Inhibition of the cAMP-stimulated beta-galactosidase transcription in SK-N-MC cells expressing the human Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 370nMAssay Description:Inhibition of recombinant human SphK2 expressed in baculovirus infected Sf9 cells assessed as decrease in [33P]S1P production using varying level of ...More data for this Ligand-Target Pair
Affinity DataKi: 390nMAssay Description:Inhibition of recombinant human SPHK2 at using sphingosine as substrate after 30 mins in presence of gamma-[32P]-ATP by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Inhibition of recombinant mouse SphK2 expressed in baculovirus infected Sf9 insect cells using D-erythro-sphingosine as substrate measured after 30 m...More data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Functional Histamine H1 receptor antagonistic activity in vitro assay on guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Inhibition of recombinant human SphK2 assessed as decrease in [33P]SIP production using sphingosine as substrate in presence of [gamma33P]-ATP by sci...More data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Inhibition of purified human SphK2 assessed as inhibition of formation of [33P]-S1P after 50 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 500nM ΔG°: -37.4kJ/moleT: 37°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
Affinity DataKi: 900nMAssay Description:Inhibition of human recombinant SphK2 using sphingosine as substrate incubated for 20 mins by scintillation counting analysis in presence of [gamma-3...More data for this Ligand-Target Pair
Affinity DataKi: 900nMAssay Description:Inhibition of recombinant human SPHK2 at using sphingosine as substrate after 30 mins in presence of gamma-[32P]-ATP by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 951nMAssay Description:Inhibition of recombinant human SphK2 assessed as decrease in [33P]SIP production using sphingosine as substrate in presence of [gamma33P]-ATP by sci...More data for this Ligand-Target Pair
Affinity DataKi: 980nMAssay Description:Inhibition of human recombinant SphK2 using sphingosine as substrate incubated for 20 mins by scintillation counting analysis in presence of [gamma-3...More data for this Ligand-Target Pair
Affinity DataKi: 980nMAssay Description:Inhibition of human recombinant SphK2 using sphingosine as substrate incubated for 20 mins by scintillation counting analysis in presence of [gamma-3...More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Functional Histamine H3 receptor antagonistic activity in vitro assay on guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKi: 1.02E+3nMAssay Description:Inhibition of human recombinant SphK2 using sphingosine as substrate incubated for 20 mins by scintillation counting analysis in presence of [gamma-3...More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Inhibition of human recombinant SphK2 expressed in Sf9 cells assessed as radiolabeled products using 10 uM sphingosine and 10 uM gamma[32P]ATP by liq...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Inhibition of human recombinant SphK2 expressed in Sf9 cells assessed as radiolabeled products using 10 uM sphingosine and 10 uM gamma[32P]ATP by liq...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Inhibition of recombinant human SphK2 expressed in baculovirus infected sf9 cells using D-erythro-sphingosine as substrate after 20 mins in presence ...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Inhibition of human SphK2 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of recombinant mouse SPHK2 using sphingosine as substrate in presence ATPMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of human recombinant SphK2 expressed in Sf9 cells assessed as radiolabeled products using 10 uM sphingosine and 10 uM gamma[32P]ATP by liq...More data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Functional H2 receptor antagonistic activity in vitro assay on the isolated spontaneously beating guinea-pig right atriumMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:SLR080811, prepared as the HCl salt, was tested first at recombinant SphK1 and SphK2 using a broken cell assay.More data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of recombinant SK2 (unknown origin) expressed in Sf9 cells assessed as [33P]S1P formation using D-erythro sphingosine as substrate and gam...More data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of SphK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of recombinant SK2 (unknown origin) expressed in Sf9 insect cells using D-erythro-sphingosine as substrate measured in presence of [gamma3...More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of human recombinant SphK2 using sphingosine as substrate incubated for 20 mins by scintillation counting analysis in presence of [gamma-3...More data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:SLR080811, prepared as the HCl salt, was tested first at recombinant SphK1 and SphK2 using a broken cell assay.More data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Inhibition of human recombinant SphK2 expressed in Sf9 cells assessed as radiolabeled products using 10 uM sphingosine and 10 uM gamma[32P]ATP by liq...More data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nM ΔG°: -34.6kJ/moleT: 37°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nM ΔG°: -33.8kJ/moleT: 37°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
