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Report error Found 464 Enz. Inhib. hit(s) with Target = 'Thymidine phosphorylase'
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50122764(CHEMBL122679 | 2-Amino-1-(5-bromo-2,6-dioxo-1,2,3,...)
Affinity DataIC50: 1.90nMAssay Description:Compound was evaluated for its inhibitory activity against recombinant purified Escherichia coli Thymidine PhosphorylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Rat)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50378690(CHEMBL597306)
Affinity DataIC50: 11nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Rat)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50378691(CHEMBL609919)
Affinity DataIC50: 15nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50122764(CHEMBL122679 | 2-Amino-1-(5-bromo-2,6-dioxo-1,2,3,...)
Affinity DataIC50: 19nMAssay Description:Inhibitory activity against Escherichia coli thymidine phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50122764(CHEMBL122679 | 2-Amino-1-(5-bromo-2,6-dioxo-1,2,3,...)
Affinity DataIC50: 19nMAssay Description:Inhibitory concentration against human thymidine phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50121753(1-(5-Chloro-2,6-dioxo-1,2,3,6-tetrahydro-pyrimidin...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against Escherichia coli thymidine phosphorylaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20079(5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...)
Affinity DataIC50: 20nMAssay Description:Compound was evaluated for its inhibitory activity against recombinant purified Escherichia coli Thymidine PhosphorylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20079(5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Thymidine phosphorylase from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50122764(CHEMBL122679 | 2-Amino-1-(5-bromo-2,6-dioxo-1,2,3,...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20079(5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...)
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration against thymidine phosphorylase of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50274904(CHEMBL4129617)
Affinity DataIC50: 20nMAssay Description:Inhibition of thymidine phosphorylase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50122771(CHEMBL66531 | CHEMBL193667 | 2-Amino-1-(5-chloro-2...)
Affinity DataIC50: 21nMAssay Description:Compound was evaluated for its inhibitory activity against recombinant purified Escherichia coli Thymidine PhosphorylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20079(5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...)
Affinity DataIC50: 23nMAssay Description:Inhibitory concentration against human thymidine phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20079(5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...)
Affinity DataIC50: 30nMAssay Description:Inhibition of thymidine phosphorylase (unknown origin) using thymidine as substrate after 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20079(5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant thymidine phosphorylase by [3H]thymidine incorporation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20079(5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...)
Affinity DataIC50: 35nMAssay Description:Competitive inhibition of human thymidine phosphorylase in presence of thymidineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20079(5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human thymidine phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50121753(1-(5-Chloro-2,6-dioxo-1,2,3,6-tetrahydro-pyrimidin...)
Affinity DataIC50: 35nMAssay Description:Inhibitory concentration against human thymidine phosphorylase TPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20079(5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human placenta thymidine phosphorylase using [6-3H]dThd as substrate after 5 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20079(5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human placenta thymidine phosphorylase using [6-3H]dThd as substrate after 5 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20079(5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human placental thymidine phosphorylase using [6-3H]dThd as substrate after 5 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20079(5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...)
Affinity DataIC50: 35nMAssay Description:Inhibition of Escherichia coli thymidine phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50122770(6-amino-5-bromo-1,2,3,4-tetrahydropyrimidine-2,4-d...)
Affinity DataIC50: 35nMAssay Description:Inhibition of thymidine phosphorylase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50531739(MA-1 | TPI (freebase) | Tipiracil)
Affinity DataIC50: 35nMAssay Description:Inhibition of thymidine phosphorylase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20079(5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...)
Affinity DataIC50: 36nMAssay Description:Inhibition of Escherichia coli Thymidine phosphorylase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Rat)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50378684(CHEMBL599543)
Affinity DataIC50: 45nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Rat)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50378689(CHEMBL599563)
Affinity DataIC50: 45nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50122771(CHEMBL66531 | CHEMBL193667 | 2-Amino-1-(5-chloro-2...)
Affinity DataIC50: 49nMAssay Description:Inhibitory concentration against human thymidine phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50122768(CHEMBL303346 | CHEMBL194335 | 2-Amino-1-(2,6-dioxo...)
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against human thymidine phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50464651(CHEMBL4293861)
Affinity DataIC50: 120nMAssay Description:Inhibition of thymidine phosphorylase (unknown origin) using thymidine as substrate after 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50531732(CHEMBL4455140)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human thymidine phosphorylase expressed in Escherichia coli Rosetta (DE3) cells using thymidine as substrate after 1 min by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Rat)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50378687(CHEMBL598328)
Affinity DataIC50: 190nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Rat)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50378688(CHEMBL599562)
Affinity DataIC50: 220nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Rat)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50378685(CHEMBL599544)
Affinity DataIC50: 250nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Rat)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50378692(CHEMBL611383)
Affinity DataIC50: 300nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50443422(CHEMBL3087264)
Affinity DataIC50: 350nMAssay Description:Inhibition of human thymidine phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Rat)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50378686(CHEMBL598327)
Affinity DataIC50: 350nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50122768(CHEMBL303346 | CHEMBL194335 | 2-Amino-1-(2,6-dioxo...)
Affinity DataIC50: 560nMAssay Description:Compound was evaluated for its inhibitory activity against recombinant purified Escherichia coli Thymidine PhosphorylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50122768(CHEMBL303346 | CHEMBL194335 | 2-Amino-1-(2,6-dioxo...)
Affinity DataIC50: 560nMAssay Description:Inhibitory concentration against thymidine phosphorylase of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Rat)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50378683(CHEMBL599132)
Affinity DataIC50: 750nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50531729(CHEMBL4469338)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human thymidine phosphorylase expressed in Escherichia coli Rosetta (DE3) cells using thymidine as substrate after 1 min by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50531734(CHEMBL4468378)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human thymidine phosphorylase expressed in Escherichia coli Rosetta (DE3) cells using thymidine as substrate after 1 min by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50464648(CHEMBL4291353)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of thymidine phosphorylase (unknown origin) using thymidine as substrate after 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50122765(6-(2-Nitro-imidazol-1-ylmethyl)-1H-pyrimidine-2,4-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Compound was evaluated for its inhibitory activity against recombinant purified Escherichia coli Thymidine PhosphorylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50122770(6-amino-5-bromo-1,2,3,4-tetrahydropyrimidine-2,4-d...)
Affinity DataIC50: 1.60E+3nMAssay Description:Compound was evaluated for its inhibitory activity against recombinant purified Escherichia coli Thymidine PhosphorylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50122770(6-amino-5-bromo-1,2,3,4-tetrahydropyrimidine-2,4-d...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Thymidine phosphorylase from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50122770(6-amino-5-bromo-1,2,3,4-tetrahydropyrimidine-2,4-d...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory concentration against thymidine phosphorylase of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20033(6-(azetidin-1-yl)-5-bromo-1,3-diazinane-2,4-dione ...)
Affinity DataIC50: 2.00E+3nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20051(5-bromo-6-[4-(5-bromo-2,6-dioxo-1,2,3,6-tetrahydro...)
Affinity DataIC50: 2.30E+3nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50194179(1-(cyclopropyl)methyl-5'-O-tritylinosine | CHEMBL3...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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