Compile Data Set for Download or QSAR
Report error Found 58 Enz. Inhib. hit(s) with Target = 'm7GpppX diphosphatase'
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36534(D156095)
Affinity DataEC50:  104nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36535(D157554)
Affinity DataEC50:  921nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36536(D153215)
Affinity DataEC50:  243nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50512855(CHEMBL4465809)
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of DcpS (unknown origin) using m7GpppA as substrate by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50232526(5-((2,4-difluorophenoxy)methyl)quinazoline-2,4-dia...)
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50232534(5-((2-fluorophenoxy)methyl)quinazoline-2,4-diamine...)
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50237216(CHEMBL4080254)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50232538(D156844 | CHEMBL251429 | 5-((1-(2-fluorobenzyl)pip...)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50237201(CHEMBL4082618)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50232589(5-((3-chlorophenoxy)methyl)quinazoline-2,4-diamine...)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50237200(CHEMBL4072132)
Affinity DataIC50: 0.0690nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36530(D157493)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50237199(CHEMBL4077061)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50237203(CHEMBL250072)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50237205(CHEMBL398675)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50237209(CHEMBL4062544)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50237211(CHEMBL4061457)
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50237210(CHEMBL399673)
Affinity DataIC50: 0.290nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36534(D156095)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50237217(CHEMBL342595)
Affinity DataIC50: 1nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50237202(CHEMBL4103454)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50237198(CHEMBL4068466)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50237218(CHEMBL4072481)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50232566(5-(3-chlorobenzyloxy)quinazoline-2,4-diamine | CHE...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50237217(CHEMBL342595)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of DcpS (unknown origin) using m7GpppA as substrate by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50237200(CHEMBL4072132)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human DcpSMore data for this Ligand-Target Pair
In DepthDetails
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50232538(D156844 | CHEMBL251429 | 5-((1-(2-fluorobenzyl)pip...)
Affinity DataIC50: 7.62nM EC50:  4nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50237204(CHEMBL343543)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36533(D157555)
Affinity DataIC50: 9.38nM EC50:  108nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50237206(CHEMBL4075292)
Affinity DataIC50: 11nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50237212(CHEMBL4100442)
Affinity DataIC50: 12nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50237214(CHEMBL4084161)
Affinity DataIC50: 14nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50237208(CHEMBL4090641)
Affinity DataIC50: 16nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36531(D158963)
Affinity DataIC50: 23.4nM EC50:  223nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50613666(CHEMBL4085817)
Affinity DataIC50: 36nMAssay Description:Inhibition of human DcpSMore data for this Ligand-Target Pair
In DepthDetails
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36530(D157493)
Affinity DataIC50: 43.9nM EC50:  67nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36532(D158885)
Affinity DataIC50: 101nM EC50:  795nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM14323(quinazoline-2,4-diamine | Fragment 20)
Affinity DataIC50: 143nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50237219(CHEMBL4093512)
Affinity DataIC50: 334nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36529(D156676)
Affinity DataIC50: 339nM EC50:  2.54E+3nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50316303(((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human DCPS using m7GMPF as substrate after 30 mins by nucleoside 5'-fluorophosphate probe based HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50237213(CHEMBL4102384)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50237215(CHEMBL4075512)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50316304(((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-...)
Affinity DataIC50: 4.22E+4nMAssay Description:Inhibition of human DCPS using m7GMPF as substrate after 30 mins by nucleoside 5'-fluorophosphate probe based HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50452630(CHEMBL4203412)
Affinity DataIC50: 2.44E+5nMAssay Description:Inhibition of human DCPS using m7GMPF as substrate after 30 mins by nucleoside 5'-fluorophosphate probe based HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50543778(CHEMBL4640425)
Affinity DataKi:  410nMAssay Description:Inhibition of human DcpS using pyrene labeled 7-methylguanosine triphosphate as substrate preincubated for 15 mins followed by enzyme addition by flu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50316303(((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-...)
Affinity DataKi:  680nMAssay Description:Inhibition of human DcpS using pyrene labeled 7-methylguanosine triphosphate as substrate preincubated for 15 mins followed by enzyme addition by flu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50543779(CHEMBL4635767)
Affinity DataKi:  730nMAssay Description:Inhibition of human DcpS using pyrene labeled 7-methylguanosine triphosphate as substrate preincubated for 15 mins followed by enzyme addition by flu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50543779(CHEMBL4635767)
Affinity DataKi:  740nMAssay Description:Inhibition of human DcpS using pyrene labeled 7-methylguanosine triphosphate as substrate preincubated for 15 mins followed by enzyme addition by flu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50543775(CHEMBL4640985)
Affinity DataKi:  870nMAssay Description:Inhibition of human DcpS using pyrene labeled 7-methylguanosine triphosphate as substrate preincubated for 15 mins followed by enzyme addition by flu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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