Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50015839
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161488(Des-His1[Glu9]glucagon-NH2 | CHEMBL439289)
Affinity DataIC50: 18nMAssay Description:Inhibition of glucagon induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161488(Des-His1[Glu9]glucagon-NH2 | CHEMBL439289)
Affinity DataIC50: 18nMAssay Description:Inhibitory concentration towards binding of [125I]glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50410091(CHEMBL2112992)
Affinity DataIC50: 34nMAssay Description:Inhibition of glucagon induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161498(4-Cyano-5-(2-ethyl-butyrylamino)-3-methyl-thiophen...)
Affinity DataIC50: 41nMAssay Description:Inhibition of glucagon induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161497(N-{3-Cyano-6-[(2,4-dichloro-benzyl)-isopropyl-amin...)
Affinity DataIC50: 59nMAssay Description:Inhibition of glucagon induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161496(N-{3-Cyano-6-[(2,4-dichloro-benzyl)-methyl-amino]-...)
Affinity DataIC50: 63nMAssay Description:Inhibition of glucagon induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50410091(CHEMBL2112992)
Affinity DataIC50: 89nMAssay Description:Inhibitory concentration towards binding of [125I]glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161496(N-{3-Cyano-6-[(2,4-dichloro-benzyl)-methyl-amino]-...)
Affinity DataIC50: 92nMAssay Description:Inhibitory concentration towards binding of [125I]glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161497(N-{3-Cyano-6-[(2,4-dichloro-benzyl)-isopropyl-amin...)
Affinity DataIC50: 129nMAssay Description:Inhibitory concentration towards binding of [125I]glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161494(N-[3-Cyano-6-(1,1-dimethyl-propyl)-4,5,6,7-tetrahy...)
Affinity DataIC50: 129nMAssay Description:Inhibition of glucagon induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161489(N-{3-Cyano-6-[methyl-(1,2,3,4-tetrahydro-naphthale...)
Affinity DataIC50: 139nMAssay Description:Inhibitory concentration towards binding of [125I]glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161489(N-{3-Cyano-6-[methyl-(1,2,3,4-tetrahydro-naphthale...)
Affinity DataIC50: 139nMAssay Description:Inhibitory concentration towards binding of [125I]glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161498(4-Cyano-5-(2-ethyl-butyrylamino)-3-methyl-thiophen...)
Affinity DataIC50: 153nMAssay Description:Inhibitory concentration towards binding of [125I]glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161489(N-{3-Cyano-6-[methyl-(1,2,3,4-tetrahydro-naphthale...)
Affinity DataIC50: 158nMAssay Description:Inhibition of glucagon induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161489(N-{3-Cyano-6-[methyl-(1,2,3,4-tetrahydro-naphthale...)
Affinity DataIC50: 158nMAssay Description:Inhibition of glucagon induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161494(N-[3-Cyano-6-(1,1-dimethyl-propyl)-4,5,6,7-tetrahy...)
Affinity DataIC50: 181nMAssay Description:Inhibitory concentration towards binding of [125I]glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50410090(CHEMBL2112991)
Affinity DataIC50: 185nMAssay Description:Inhibition of glucagon induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50410090(CHEMBL2112991)
Affinity DataIC50: 368nMAssay Description:Inhibitory concentration towards binding of [125I]glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161492(6-(1,1-Dimethyl-propyl)-2-(2-ethyl-butyrylamino)-4...)
Affinity DataIC50: 870nMAssay Description:Inhibitory concentration towards binding of [125I]glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161495(N-[3-Cyano-5-(5-isobutyl-[1,3,4]oxadiazol-2-yl)-4-...)
Affinity DataIC50: 3.21E+3nMAssay Description:Inhibitory concentration towards binding of [125I]glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161490(N-[6-(Benzyl-methyl-amino)-3-cyano-4,5,6,7-tetrahy...)
Affinity DataIC50: 3.82E+3nMAssay Description:Inhibitory concentration towards binding of [125I]glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161499(4-Bromo-N-[3-cyano-6-(1,1-dimethyl-propyl)-4,5,6,7...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory concentration towards binding of [125I]glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed