Compile Data Set for Download or QSAR
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Found 24 Enz. Inhib. hit(s) with all data for entry = 50016276
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50056272((1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dic...)
Affinity DataKi:  74nMAssay Description:Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50056272((1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dic...)
Affinity DataKi:  93nMAssay Description:Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50167033((1S,2S,3R,5R,6S)-2-Amino-3-methyl-bicyclo[3.1.0]he...)
Affinity DataKi:  146nMAssay Description:Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50167032((1S,2S,4R,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...)
Affinity DataKi:  409nMAssay Description:Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50167032((1S,2S,4R,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...)
Affinity DataKi:  409nMAssay Description:Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50167034((1S,2S,4S,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...)
Affinity DataKi:  511nMAssay Description:Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50167032((1S,2S,4R,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...)
Affinity DataKi:  570nMAssay Description:Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50167032((1S,2S,4R,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...)
Affinity DataKi:  570nMAssay Description:Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50167034((1S,2S,4S,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...)
Affinity DataKi:  635nMAssay Description:Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50167033((1S,2S,3R,5R,6S)-2-Amino-3-methyl-bicyclo[3.1.0]he...)
Affinity DataKi:  983nMAssay Description:Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50167031((1R,2R,4S,5S,6R)-2-Amino-4-methyl-bicyclo[3.1.0]he...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50167031((1R,2R,4S,5S,6R)-2-Amino-4-methyl-bicyclo[3.1.0]he...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50167033((1S,2S,3R,5R,6S)-2-Amino-3-methyl-bicyclo[3.1.0]he...)
Affinity DataIC50:  1.75E+3nMAssay Description:Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50167032((1S,2S,4R,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...)
Affinity DataIC50:  2.94E+3nMAssay Description:Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50167032((1S,2S,4R,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...)
Affinity DataIC50:  2.94E+3nMAssay Description:Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50167033((1S,2S,3R,5R,6S)-2-Amino-3-methyl-bicyclo[3.1.0]he...)
Affinity DataIC50:  9.83E+3nMAssay Description:Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50167031((1R,2R,4S,5S,6R)-2-Amino-4-methyl-bicyclo[3.1.0]he...)
Affinity DataEC50: >1.00E+5nMAssay Description:Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50167034((1S,2S,4S,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...)
Affinity DataEC50:  34nMAssay Description:Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50167031((1R,2R,4S,5S,6R)-2-Amino-4-methyl-bicyclo[3.1.0]he...)
Affinity DataEC50: >1.00E+5nMAssay Description:Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50056272((1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dic...)
Affinity DataEC50:  10nMAssay Description:Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu2 receptorMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50167032((1S,2S,4R,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...)
Affinity DataEC50:  397nMAssay Description:Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50056272((1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dic...)
Affinity DataEC50:  38nMAssay Description:Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu3 receptorMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50167034((1S,2S,4S,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...)
Affinity DataEC50:  45nMAssay Description:Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50167032((1S,2S,4R,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...)
Affinity DataEC50:  397nMAssay Description:Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed