Compile Data Set for Download or QSAR
maximum 50k data
Found 46 Enz. Inhib. hit(s) with all data for entry = 3500
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35683(5H-1-benzazepin-5-ylidene acetamide, 1k)
Affinity DataKi:  3.40nM ΔG°:  -48.0kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35673(5H-1-benzazepin-5-ylidene acetamide, 1a | BMC16952...)
Affinity DataKi:  4.80nM ΔG°:  -47.2kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35677(5H-1-benzazepin-5-ylidene acetamide, 1e)
Affinity DataKi:  5.60nM ΔG°:  -46.8kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35681(5H-1-benzazepin-5-ylidene acetamide, 1i)
Affinity DataKi:  7.40nM ΔG°:  -46.1kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35666(BMC173130 Compound 1t | benzazepinelidene acetamid...)
Affinity DataKi:  9.70nM ΔG°:  -45.4kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35679(5H-1-benzazepin-5-ylidene acetamide, 1g)
Affinity DataKi:  10nM ΔG°:  -45.4kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35684(5H-1-benzazepin-5-ylidene acetamide, 1l)
Affinity DataKi:  11nM ΔG°:  -45.1kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35694(5H-1-benzazepin-5-ylidene acetamide, 1w)
Affinity DataKi:  11nM ΔG°:  -45.1kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35686(5H-1-benzazepin-5-ylidene acetamide, 1n)
Affinity DataKi:  11nM ΔG°:  -45.1kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35685(5H-1-benzazepin-5-ylidene acetamide, 1m)
Affinity DataKi:  11nM ΔG°:  -45.1kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35680(5H-1-benzazepin-5-ylidene acetamide, 1h)
Affinity DataKi:  11nM ΔG°:  -45.1kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35687(5H-1-benzazepin-5-ylidene acetamide, 1o)
Affinity DataKi:  12nM ΔG°:  -44.9kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35691(5H-1-benzazepin-5-ylidene acetamide, 1s)
Affinity DataKi:  13nM ΔG°:  -45.0kJ/moleT: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35682(5H-1-benzazepin-5-ylidene acetamide, 1j)
Affinity DataKi:  14nM ΔG°:  -44.5kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35675(5H-1-benzazepin-5-ylidene acetamide, 1c)
Affinity DataKi:  15nM ΔG°:  -44.7kJ/moleT: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35678(5H-1-benzazepin-5-ylidene acetamide, 1f)
Affinity DataKi:  16nM ΔG°:  -44.2kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35691(5H-1-benzazepin-5-ylidene acetamide, 1s)
Affinity DataKi:  18nM ΔG°:  -43.9kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35676(5H-1-benzazepin-5-ylidene acetamide, 1d)
Affinity DataKi:  19nM ΔG°:  -43.8kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35675(5H-1-benzazepin-5-ylidene acetamide, 1c)
Affinity DataKi:  20nM ΔG°:  -43.6kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35674(5H-1-benzazepin-5-ylidene acetamide, 1b)
Affinity DataKi:  21nM ΔG°:  -43.5kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35681(5H-1-benzazepin-5-ylidene acetamide, 1i)
Affinity DataKi:  22nM ΔG°:  -43.7kJ/moleT: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35693(5H-1-benzazepin-5-ylidene acetamide, 1v)
Affinity DataKi:  22nM ΔG°:  -43.4kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35689(5H-1-benzazepin-5-ylidene acetamide, 1q)
Affinity DataKi:  25nM ΔG°:  -43.1kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35673(5H-1-benzazepin-5-ylidene acetamide, 1a | BMC16952...)
Affinity DataKi:  26nM ΔG°:  -43.3kJ/moleT: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35688(5H-1-benzazepin-5-ylidene acetamide, 1p)
Affinity DataKi:  27nM ΔG°:  -42.9kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35666(BMC173130 Compound 1t | benzazepinelidene acetamid...)
Affinity DataKi:  28nM ΔG°:  -43.1kJ/moleT: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35677(5H-1-benzazepin-5-ylidene acetamide, 1e)
Affinity DataKi:  30nM ΔG°:  -42.9kJ/moleT: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35690(5H-1-benzazepin-5-ylidene acetamide, 1r)
Affinity DataKi:  33nM ΔG°:  -42.4kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35679(5H-1-benzazepin-5-ylidene acetamide, 1g)
Affinity DataKi:  38nM ΔG°:  -42.4kJ/moleT: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35674(5H-1-benzazepin-5-ylidene acetamide, 1b)
Affinity DataKi:  40nM ΔG°:  -42.2kJ/moleT: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35694(5H-1-benzazepin-5-ylidene acetamide, 1w)
Affinity DataKi:  40nM ΔG°:  -42.2kJ/moleT: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35676(5H-1-benzazepin-5-ylidene acetamide, 1d)
Affinity DataKi:  43nM ΔG°:  -42.0kJ/moleT: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35685(5H-1-benzazepin-5-ylidene acetamide, 1m)
Affinity DataKi:  43nM ΔG°:  -42.0kJ/moleT: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35683(5H-1-benzazepin-5-ylidene acetamide, 1k)
Affinity DataKi:  43nM ΔG°:  -42.0kJ/moleT: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35684(5H-1-benzazepin-5-ylidene acetamide, 1l)
Affinity DataKi:  44nM ΔG°:  -42.0kJ/moleT: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35678(5H-1-benzazepin-5-ylidene acetamide, 1f)
Affinity DataKi:  47nM ΔG°:  -41.8kJ/moleT: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35680(5H-1-benzazepin-5-ylidene acetamide, 1h)
Affinity DataKi:  48nM ΔG°:  -41.8kJ/moleT: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35692(5H-1-benzazepin-5-ylidene acetamide, 1u)
Affinity DataKi:  53nM ΔG°:  -41.2kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35686(5H-1-benzazepin-5-ylidene acetamide, 1n)
Affinity DataKi:  55nM ΔG°:  -41.4kJ/moleT: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35682(5H-1-benzazepin-5-ylidene acetamide, 1j)
Affinity DataKi:  57nM ΔG°:  -41.3kJ/moleT: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35692(5H-1-benzazepin-5-ylidene acetamide, 1u)
Affinity DataKi:  59nM ΔG°:  -41.3kJ/moleT: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35687(5H-1-benzazepin-5-ylidene acetamide, 1o)
Affinity DataKi:  72nM ΔG°:  -40.8kJ/moleT: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35688(5H-1-benzazepin-5-ylidene acetamide, 1p)
Affinity DataKi:  72nM ΔG°:  -40.8kJ/moleT: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35690(5H-1-benzazepin-5-ylidene acetamide, 1r)
Affinity DataKi:  190nM ΔG°:  -38.4kJ/moleT: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35693(5H-1-benzazepin-5-ylidene acetamide, 1v)
Affinity DataKi:  230nM ΔG°:  -37.9kJ/moleT: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35689(5H-1-benzazepin-5-ylidene acetamide, 1q)
Affinity DataKi:  6.30E+3nM ΔG°:  -29.7kJ/moleT: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed