Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 2556
TargetNitric oxide synthase, brain(Rat)
Northwestern University

LigandPNGBDBM21962(3-[(4S)-4-amino-5-[(2-aminoethyl)(hydroxy)amino]pe...)
Affinity DataKi:  120nM ΔG°:  -40.2kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

LigandPNGBDBM21960(JMC522060 Compound 2 | CHEMBL227937 | 3-[(4S)-4-am...)
Affinity DataKi:  170nM ΔG°:  -39.3kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

LigandPNGBDBM21964((2S,4R)-4-[(2S)-2-amino-N-hydroxy-5-(1-nitrocarbam...)
Affinity DataKi:  310nM ΔG°:  -37.8kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

LigandPNGBDBM21961(JMC522060 Compound 3 | (2S,4R)-4-[(2S)-2-amino-5-(...)
Affinity DataKi:  330nM ΔG°:  -37.6kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

LigandPNGBDBM21963(3-[(4S)-4-amino-5-[1-(2-aminoethyl)hydrazin-1-yl]p...)
Affinity DataKi:  560nM ΔG°:  -36.3kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

LigandPNGBDBM50225106(NG-nitroarginine | 2-Amino-5-(N'-nitro-guanidino)-...)
Affinity DataKi:  610nM ΔG°:  -36.1kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

LigandPNGBDBM50225106(NG-nitroarginine | 2-Amino-5-(N'-nitro-guanidino)-...)
Affinity DataKi:  720nM ΔG°:  -35.6kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

LigandPNGBDBM50225106(NG-nitroarginine | 2-Amino-5-(N'-nitro-guanidino)-...)
Affinity DataKi:  4.28E+3nM ΔG°:  -31.2kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

LigandPNGBDBM21962(3-[(4S)-4-amino-5-[(2-aminoethyl)(hydroxy)amino]pe...)
Affinity DataKi:  1.60E+4nM ΔG°:  -27.8kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

LigandPNGBDBM21964((2S,4R)-4-[(2S)-2-amino-N-hydroxy-5-(1-nitrocarbam...)
Affinity DataKi:  1.60E+4nM ΔG°:  -27.8kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

LigandPNGBDBM21961(JMC522060 Compound 3 | (2S,4R)-4-[(2S)-2-amino-5-(...)
Affinity DataKi:  1.70E+4nM ΔG°:  -27.7kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

LigandPNGBDBM21960(JMC522060 Compound 2 | CHEMBL227937 | 3-[(4S)-4-am...)
Affinity DataKi:  1.80E+4nM ΔG°:  -27.5kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

LigandPNGBDBM21964((2S,4R)-4-[(2S)-2-amino-N-hydroxy-5-(1-nitrocarbam...)
Affinity DataKi:  3.50E+4nM ΔG°:  -25.9kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

LigandPNGBDBM21963(3-[(4S)-4-amino-5-[1-(2-aminoethyl)hydrazin-1-yl]p...)
Affinity DataKi:  3.70E+4nM ΔG°:  -25.7kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

LigandPNGBDBM21961(JMC522060 Compound 3 | (2S,4R)-4-[(2S)-2-amino-5-(...)
Affinity DataKi:  7.20E+4nM ΔG°:  -24.0kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

LigandPNGBDBM21962(3-[(4S)-4-amino-5-[(2-aminoethyl)(hydroxy)amino]pe...)
Affinity DataKi:  7.30E+4nM ΔG°:  -24.0kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

LigandPNGBDBM21963(3-[(4S)-4-amino-5-[1-(2-aminoethyl)hydrazin-1-yl]p...)
Affinity DataKi:  1.03E+5nM ΔG°:  -23.1kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

LigandPNGBDBM21960(JMC522060 Compound 2 | CHEMBL227937 | 3-[(4S)-4-am...)
Affinity DataKi:  1.91E+5nM ΔG°:  -21.6kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed