Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 3450
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandChemical structure of BindingDB Monomer ID 34143BDBM34143(CHEMBL175835 | E-6837)
Affinity DataKi:  0.700nM ΔG°:  -54.4kJ/mole EC50:  0.290nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandChemical structure of BindingDB Monomer ID 34144BDBM34144((R)-5a | WAY-466)
Affinity DataKi:  1nM ΔG°:  -53.4kJ/mole EC50:  0.400nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandChemical structure of BindingDB Monomer ID 34145BDBM34145(pyrrolidinylindole, (R)-5b)
Affinity DataKi:  0.400nM ΔG°:  -55.8kJ/mole EC50:  4.5nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandChemical structure of BindingDB Monomer ID 34147BDBM34147(CHEMBL425196 | pyrrolidinylindole, 6)
Affinity DataKi:  1nM ΔG°:  -53.4kJ/mole EC50:  53.3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandChemical structure of BindingDB Monomer ID 34148BDBM34148(CHEMBL371292 | piperidinylindole, 7)
Affinity DataKi:  2nM ΔG°:  -51.6kJ/mole EC50:  24nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandChemical structure of BindingDB Monomer ID 34141BDBM34141(CHEMBL76237 | MS-245)
Affinity DataKi:  2nM ΔG°:  -51.6kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandChemical structure of BindingDB Monomer ID 21358BDBM21358(2-[1-({6-chloroimidazo[2,1-b][1,3]thiazole-5-}sulf...)
Affinity DataKi:  2nM ΔG°:  -51.6kJ/mole EC50:  6.5nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandChemical structure of BindingDB Monomer ID 34152BDBM34152(CHEMBL362628 | E-6801)
Affinity DataKi:  2.20nM ΔG°:  -51.4kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandChemical structure of BindingDB Monomer ID 34149BDBM34149(CHEMBL94422 | N-benzenesulfonylgramine antagonist,...)
Affinity DataKi:  3nM ΔG°:  -50.6kJ/mole EC50:  880nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandChemical structure of BindingDB Monomer ID 34156BDBM34156(indenylsulfonamide, 28)
Affinity DataKi:  3nM ΔG°:  -50.6kJ/mole IC50: 1.60E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandChemical structure of BindingDB Monomer ID 34153BDBM34153(CHEMBL476006 | indenylsulfonamide, 14)
Affinity DataKi:  4.5nM ΔG°:  -49.6kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandChemical structure of BindingDB Monomer ID 34146BDBM34146(pyrrolidinylindole, (S)-5b)
Affinity DataKi:  10nM ΔG°:  -47.5kJ/mole EC50:  21.6nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandChemical structure of BindingDB Monomer ID 34151BDBM34151(CHEMBL372109 | N-arenesulfonylindole antagonist, 1...)
Affinity DataKi:  10nM ΔG°:  -47.5kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandChemical structure of BindingDB Monomer ID 34154BDBM34154(CHEMBL515307 | indenylsulfonamide, 15)
Affinity DataKi:  10nM ΔG°:  -47.5kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandChemical structure of BindingDB Monomer ID 34150BDBM34150(CHEMBL328816 | 4-(3-methyl-1H-indole-1-sulfonyl)an...)
Affinity DataKi:  12nM ΔG°:  -47.0kJ/mole EC50:  320nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandChemical structure of BindingDB Monomer ID 34142BDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | EMDT | ...)
Affinity DataKi:  16nM ΔG°:  -46.3kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandChemical structure of BindingDB Monomer ID 34158BDBM34158(indenylsulfonamide, 30)
Affinity DataKi:  18nM ΔG°:  -46.0kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandChemical structure of BindingDB Monomer ID 34159BDBM34159(isomeric mixture (70% 5-indenyl, 30% 6-indenyl) | ...)
Affinity DataKi:  43nM ΔG°:  -43.7kJ/mole IC50: 3.00E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandChemical structure of BindingDB Monomer ID 34162BDBM34162(indenylsulfonamide, 52)
Affinity DataKi:  64nM ΔG°:  -42.7kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandChemical structure of BindingDB Monomer ID 34161BDBM34161(indenylsulfonamide, 51)
Affinity DataKi:  80nM ΔG°:  -42.1kJ/mole IC50: 2.40E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandChemical structure of BindingDB Monomer ID 34155BDBM34155(indenylsulfonamide, 26)
Affinity DatapH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandChemical structure of BindingDB Monomer ID 34157BDBM34157(indenylsulfonamide, 29)
Affinity DatapH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandChemical structure of BindingDB Monomer ID 34160BDBM34160(isomeric mixture (70% 7-indenyl, 30% 4-indenyl) | ...)
Affinity DatapH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed