Compile Data Set for Download or QSAR
maximum 50k data
Found 26 Enz. Inhib. hit(s) with all data for entry = 50030668
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50414916(CHEMBL567005)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50414917(CHEMBL567004)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50414912(CHEMBL566532)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50414918(CHEMBL567832)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50414898(CHEMBL584268)
Affinity DataIC50:  14nMAssay Description:Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50414914(CHEMBL577495)
Affinity DataIC50:  20nMAssay Description:Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50414900(CHEMBL583636)
Affinity DataIC50:  28nMAssay Description:Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50414901(CHEMBL567006)
Affinity DataIC50:  36nMAssay Description:Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50414897(CHEMBL566767)
Affinity DataIC50:  47nMAssay Description:Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50414904(CHEMBL565471)
Affinity DataIC50:  53nMAssay Description:Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM20842(3-[2-(pyridin-4-yl)-1,3-thiazol-4-yl]-1,2-dihydroq...)
Affinity DataIC50:  54nMAssay Description:Inhibition of human CDK5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50414899(CHEMBL566114)
Affinity DataIC50:  55nMAssay Description:Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50414903(CHEMBL583632)
Affinity DataIC50:  73nMAssay Description:Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM20819(3-[2-(pyridin-4-yl)-1,3-thiazol-4-yl]-1,2,3,4-tetr...)
Affinity DataIC50:  79nMAssay Description:Inhibition of human CDK5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50414902(CHEMBL568084)
Affinity DataIC50:  112nMAssay Description:Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50414915(CHEMBL566115)
Affinity DataIC50:  119nMAssay Description:Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50299869(CHEMBL577030 | ethyl 2-methyl-6-oxo-5-(2-(pyridin-...)
Affinity DataIC50:  131nMAssay Description:Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50299869(CHEMBL577030 | ethyl 2-methyl-6-oxo-5-(2-(pyridin-...)
Affinity DataIC50:  131nMAssay Description:Inhibition of human CDK5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50414905(CHEMBL565918)
Affinity DataIC50:  139nMAssay Description:Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50414908(CHEMBL566994)
Affinity DataIC50:  157nMAssay Description:Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50414913(CHEMBL578375)
Affinity DataIC50:  160nMAssay Description:Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50414907(CHEMBL584506)
Affinity DataIC50:  198nMAssay Description:Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50414910(CHEMBL567437)
Affinity DataIC50:  647nMAssay Description:Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50414906(CHEMBL567223)
Affinity DataIC50:  672nMAssay Description:Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50414909(CHEMBL568083)
Affinity DataIC50:  779nMAssay Description:Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50414911(CHEMBL565675)
Affinity DataIC50:  1.15E+4nMAssay Description:Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed