Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50032426
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329018BDBM50329018((2-(3-fluoro-2-methylbenzyl)-5-hydroxy-4-methyl-1-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329031BDBM50329031((2-(5-fluoro-2-methylphenoxy)-5-hydroxy-1-phenyl-1...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329016BDBM50329016((2-(3-fluoro-2-methylbenzyl)-6-hydroxy-1-phenyl-1H...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329017BDBM50329017((2-(3-fluoro-2-methylbenzyl)-5-hydroxy-1-phenyl-1H...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329043BDBM50329043((2-(5-fluoro-2-methylphenoxy)-1-phenyl-1H-indol-3-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329032BDBM50329032(2-(5-fluoro-2-methylphenoxy)-1-phenyl-3-(piperazin...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329047BDBM50329047((2-(3-fluoro-2-methylbenzyl)-1-phenyl-1H-indol-3-y...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329045BDBM50329045((2-(3-fluoro-2-methylphenoxy)-1-phenyl-1H-indol-3-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329015BDBM50329015((2-(3-fluoro-2-methylbenzyl)-6-methoxy-1-phenyl-1H...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329044BDBM50329044((2-(2-fluoro-6-methylphenoxy)-1-phenyl-1H-indol-3-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329048BDBM50329048((2-(2-chloro-6-fluorobenzyl)-1-phenyl-1H-indol-3-y...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329025BDBM50329025((1-cyclopentyl-2-(3-fluoro-2-methylbenzyl)-1H-indo...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329038BDBM50329038((1-phenyl-2-(o-tolyloxy)-1H-indol-3-yl)(piperazin-...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329029BDBM50329029((2-(5-fluoro-2-methylphenoxy)-6-methoxy-1-phenyl-1...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329009BDBM50329009((2-(3-fluoro-2-methylbenzyl)-6-(2-phenoxyethoxy)-1...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329013BDBM50329013((6-(2-(dimethylamino)ethoxy)-2-(5-fluoro-2-methylp...)
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329010BDBM50329010((2-(3-fluoro-2-methylbenzyl)-6-(2-hydroxyethoxy)-1...)
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329024BDBM50329024((1-cyclohexyl-2-(3-fluoro-2-methylbenzyl)-1H-indol...)
Affinity DataIC50: 34nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329011BDBM50329011((2-(3-fluoro-2-methylbenzyl)-6-(methylsulfonyl)-1-...)
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329041BDBM50329041((2-(3-fluorophenoxy)-1-phenyl-1H-indol-3-yl)(piper...)
Affinity DataIC50: 63nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329042BDBM50329042((2-(2,6-dimethylphenoxy)-1-phenyl-1H-indol-3-yl)(p...)
Affinity DataIC50: 64nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329039BDBM50329039((1-phenyl-2-(o-tolylthio)-1H-indol-3-yl)(piperazin...)
Affinity DataIC50: 71nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329008BDBM50329008((7-fluoro-2-(3-fluoro-2-methylbenzyl)-1-phenyl-1H-...)
Affinity DataIC50: 84nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329046BDBM50329046((2-benzyl-1-phenyl-1H-indol-3-yl)(piperazin-1-yl)m...)
Affinity DataIC50: 91nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329012BDBM50329012(2-(5-fluoro-2-methylphenoxy)-1-phenyl-3-(piperazin...)
Affinity DataIC50: 122nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329014BDBM50329014(2-(2-(5-fluoro-2-methylphenoxy)-1-phenyl-3-(pipera...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329022BDBM50329022((1-(2-(3-methoxypropoxy)phenyl)-2-phenoxy-1H-indol...)
Affinity DataIC50: 175nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329028BDBM50329028((2-(3-fluoro-2-methylbenzyl)-1-(6-methoxypyridin-3...)
Affinity DataIC50: 360nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329034BDBM50329034((2-phenoxy-1-phenyl-1H-indol-3-yl)(piperazin-1-yl)...)
Affinity DataIC50: 420nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329037BDBM50329037((2-(2-methoxyphenoxy)-1-phenyl-1H-indol-3-yl)(pipe...)
Affinity DataIC50: 680nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329021BDBM50329021((1-(4-fluorophenyl)-2-phenoxy-1H-indol-3-yl)(piper...)
Affinity DataIC50: 707nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329026BDBM50329026((2-(3-fluoro-2-methylbenzyl)-1-(tetrahydro-2H-pyra...)
Affinity DataIC50: 752nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329023BDBM50329023((1-(3-(3-methoxypropoxy)phenyl)-2-phenoxy-1H-indol...)
Affinity DataIC50: 763nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329040BDBM50329040((1-phenyl-2-(m-tolyloxy)-1H-indol-3-yl)(piperazin-...)
Affinity DataIC50: 773nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329030BDBM50329030((2-(5-fluoro-2-methylphenoxy)-5-methoxy-1-phenyl-1...)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329052BDBM50329052(rac-(3-(hydroxymethyl)piperazin-1-yl)(2-phenoxy-1-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329035BDBM50329035((2-(methyl(phenyl)amino)-1-phenyl-1H-indol-3-yl)(p...)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329019BDBM50329019((1,4-diazepan-1-yl)(2-phenoxy-1-phenyl-1H-indol-3-...)
Affinity DataIC50: 3.41E+3nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329033BDBM50329033((1-phenyl-2-(piperidin-1-yl)-1H-indol-3-yl)(pipera...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329051BDBM50329051(rac-(2-benzylpiperazin-1-yl)(2-phenoxy-1-phenyl-1H...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329020BDBM50329020((2-phenoxy-1-(pyridin-2-yl)-1H-indol-3-yl)(piperaz...)
Affinity DataIC50: 4.97E+3nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329049BDBM50329049(rac-(3-methylpiperazin-1-yl)(2-phenoxy-1-phenyl-1H...)
Affinity DataIC50: 6.46E+3nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329050BDBM50329050((3,3-dimethylpiperazin-1-yl)(2-phenoxy-1-phenyl-1H...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329036BDBM50329036((1-phenyl-2-(3-(trifluoromethyl)phenoxy)-1H-indol-...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329027BDBM50329027((2-(3-fluoro-2-methylbenzyl)-1-(6-hydroxypyridin-3...)
Affinity DataIC50: 9.35E+3nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed