Compile Data Set for Download or QSAR
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Found 54 Enz. Inhib. hit(s) with all data for entry = 50033196
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322512((2S,3S)-2-(3-Chlorophenyl)-5,5-dimethyl-3-propyl-m...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human DAT in HEK293 cells assessed as inhibition of [3H]dopamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322512((2S,3S)-2-(3-Chlorophenyl)-5,5-dimethyl-3-propyl-m...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human NET in HEK293 cells assessed as inhibition of [3H]norepinephrine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50341208((S,S)-2-(3'-Chlorophenyl)-3,5,5-trimethyl-4-propyl...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human NET in HEK293 cells assessed as inhibition of [3H]norepinephrine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322513((2S,3S)-2-(3-Chlorophenyl)-3-ethyl-5,5-dimethylmor...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human NET in HEK293 cells assessed as inhibition of [3H]norepinephrine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322513((2S,3S)-2-(3-Chlorophenyl)-3-ethyl-5,5-dimethylmor...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human DAT in HEK293 cells assessed as inhibition of [3H]dopamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50341207((S,S)-2-(3'-Chlorophenyl)-4-ethyl-3,5,5-trimethylm...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human NET in HEK293 cells assessed as inhibition of [3H]norepinephrine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322529((2S,3S)-2-(3-Fluorophenyl)-3,5,5-trimethylmorpholi...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human NET in HEK293 cells assessed as inhibition of [3H]norepinephrine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50341207((S,S)-2-(3'-Chlorophenyl)-4-ethyl-3,5,5-trimethylm...)
Affinity DataIC50:  44nMAssay Description:Inhibition of human DAT in HEK293 cells assessed as inhibition of [3H]dopamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322528((2S,3S)-2-(3-Bromophenyl)-3,5,5-trimethylmorpholin...)
Affinity DataIC50:  44nMAssay Description:Inhibition of human DAT in HEK293 cells assessed as inhibition of [3H]dopamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50341208((S,S)-2-(3'-Chlorophenyl)-3,5,5-trimethyl-4-propyl...)
Affinity DataIC50:  61nMAssay Description:Inhibition of human DAT in HEK293 cells assessed as inhibition of [3H]dopamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322529((2S,3S)-2-(3-Fluorophenyl)-3,5,5-trimethylmorpholi...)
Affinity DataIC50:  61nMAssay Description:Inhibition of human DAT in HEK293 cells assessed as inhibition of [3H]dopamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322531((2R,3R)-2-(3-Chlorophenyl)-3,5,5-trimethylmorpholi...)
Affinity DataIC50: >100nMAssay Description:Inhibition of human SERT in HEK293 cells assessed as inhibition of [3H]serotonin uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322532((2S,3S)-2-(3-Chlorophenyl)-3,5,5-trimethylmorpholi...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human NET in HEK293 cells assessed as inhibition of [3H]norepinephrine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322528((2S,3S)-2-(3-Bromophenyl)-3,5,5-trimethylmorpholin...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human NET in HEK293 cells assessed as inhibition of [3H]norepinephrine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322511((2S,3S)-2-(3-Chlorophenyl)-3,4,5,5-tetramethylmorp...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human NET in HEK293 cells assessed as inhibition of [3H]norepinephrine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322532((2S,3S)-2-(3-Chlorophenyl)-3,5,5-trimethylmorpholi...)
Affinity DataIC50:  220nMAssay Description:Inhibition of human DAT in HEK293 cells assessed as inhibition of [3H]dopamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322511((2S,3S)-2-(3-Chlorophenyl)-3,4,5,5-tetramethylmorp...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human DAT in HEK293 cells assessed as inhibition of [3H]dopamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322512((2S,3S)-2-(3-Chlorophenyl)-5,5-dimethyl-3-propyl-m...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human SERT in HEK293 cells assessed as inhibition of [3H]serotonin uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322532((2S,3S)-2-(3-Chlorophenyl)-3,5,5-trimethylmorpholi...)
Affinity DataIC50:  387nMAssay Description:Inhibition of human SERT in HEK293 cells assessed as inhibition of [3H]serotonin uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322528((2S,3S)-2-(3-Bromophenyl)-3,5,5-trimethylmorpholin...)
Affinity DataIC50:  390nMAssay Description:Inhibition of human SERT in HEK293 cells assessed as inhibition of [3H]serotonin uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322511((2S,3S)-2-(3-Chlorophenyl)-3,4,5,5-tetramethylmorp...)
Affinity DataIC50:  540nMAssay Description:Inhibition of human SERT in HEK293 cells assessed as inhibition of [3H]serotonin uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50341207((S,S)-2-(3'-Chlorophenyl)-4-ethyl-3,5,5-trimethylm...)
Affinity DataIC50:  790nMAssay Description:Antagonist activity at human alpha3beta4 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50341208((S,S)-2-(3'-Chlorophenyl)-3,5,5-trimethyl-4-propyl...)
Affinity DataIC50:  980nMAssay Description:Antagonist activity at human alpha3beta4 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322531((2R,3R)-2-(3-Chlorophenyl)-3,5,5-trimethylmorpholi...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human NET in HEK293 cells assessed as inhibition of [3H]norepinephrine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322528((2S,3S)-2-(3-Bromophenyl)-3,5,5-trimethylmorpholin...)
Affinity DataIC50:  1.40E+3nMAssay Description:Antagonist activity at human alpha3beta4 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50341207((S,S)-2-(3'-Chlorophenyl)-4-ethyl-3,5,5-trimethylm...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human SERT in HEK293 cells assessed as inhibition of [3H]serotonin uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322531((2R,3R)-2-(3-Chlorophenyl)-3,5,5-trimethylmorpholi...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human DAT in HEK293 cells assessed as inhibition of [3H]dopamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322531((2R,3R)-2-(3-Chlorophenyl)-3,5,5-trimethylmorpholi...)
Affinity DataIC50:  1.60E+3nMAssay Description:Antagonist activity at human alpha3beta4 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322513((2S,3S)-2-(3-Chlorophenyl)-3-ethyl-5,5-dimethylmor...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human SERT in HEK293 cells assessed as inhibition of [3H]serotonin uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322511((2S,3S)-2-(3-Chlorophenyl)-3,4,5,5-tetramethylmorp...)
Affinity DataIC50:  2.80E+3nMAssay Description:Antagonist activity at human alpha3beta4 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50341208((S,S)-2-(3'-Chlorophenyl)-3,5,5-trimethyl-4-propyl...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of human SERT in HEK293 cells assessed as inhibition of [3H]serotonin uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322512((2S,3S)-2-(3-Chlorophenyl)-5,5-dimethyl-3-propyl-m...)
Affinity DataIC50:  3.10E+3nMAssay Description:Antagonist activity at human alpha3beta4 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322532((2S,3S)-2-(3-Chlorophenyl)-3,5,5-trimethylmorpholi...)
Affinity DataIC50:  3.30E+3nMAssay Description:Antagonist activity at human alpha3beta4 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322529((2S,3S)-2-(3-Fluorophenyl)-3,5,5-trimethylmorpholi...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human SERT in HEK293 cells assessed as inhibition of [3H]serotonin uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322513((2S,3S)-2-(3-Chlorophenyl)-3-ethyl-5,5-dimethylmor...)
Affinity DataIC50:  5.60E+3nMAssay Description:Antagonist activity at human alpha3beta4 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322529((2S,3S)-2-(3-Fluorophenyl)-3,5,5-trimethylmorpholi...)
Affinity DataIC50:  5.60E+3nMAssay Description:Antagonist activity at human alpha3beta4 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50341208((S,S)-2-(3'-Chlorophenyl)-3,5,5-trimethyl-4-propyl...)
Affinity DataIC50:  5.80E+3nMAssay Description:Antagonist activity at human alpha4beta4 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50341207((S,S)-2-(3'-Chlorophenyl)-4-ethyl-3,5,5-trimethylm...)
Affinity DataIC50:  6.40E+3nMAssay Description:Antagonist activity at human alpha4beta4 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50341207((S,S)-2-(3'-Chlorophenyl)-4-ethyl-3,5,5-trimethylm...)
Affinity DataIC50:  7.20E+3nMAssay Description:Antagonist activity at human alpha4beta2 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322512((2S,3S)-2-(3-Chlorophenyl)-5,5-dimethyl-3-propyl-m...)
Affinity DataIC50:  8.00E+3nMAssay Description:Antagonist activity at human alpha4beta4 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322512((2S,3S)-2-(3-Chlorophenyl)-5,5-dimethyl-3-propyl-m...)
Affinity DataIC50:  9.50E+3nMAssay Description:Antagonist activity at human alpha4beta2 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322528((2S,3S)-2-(3-Bromophenyl)-3,5,5-trimethylmorpholin...)
Affinity DataIC50:  1.10E+4nMAssay Description:Antagonist activity at human alpha4beta4 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50341208((S,S)-2-(3'-Chlorophenyl)-3,5,5-trimethyl-4-propyl...)
Affinity DataIC50:  1.20E+4nMAssay Description:Antagonist activity at human alpha4beta2 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322528((2S,3S)-2-(3-Bromophenyl)-3,5,5-trimethylmorpholin...)
Affinity DataIC50:  1.20E+4nMAssay Description:Antagonist activity at human alpha4beta2 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322531((2R,3R)-2-(3-Chlorophenyl)-3,5,5-trimethylmorpholi...)
Affinity DataIC50:  1.20E+4nMAssay Description:Antagonist activity at human alpha4beta4 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322513((2S,3S)-2-(3-Chlorophenyl)-3-ethyl-5,5-dimethylmor...)
Affinity DataIC50:  1.40E+4nMAssay Description:Antagonist activity at human alpha4beta2 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322513((2S,3S)-2-(3-Chlorophenyl)-3-ethyl-5,5-dimethylmor...)
Affinity DataIC50:  1.50E+4nMAssay Description:Antagonist activity at human alpha4beta4 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322511((2S,3S)-2-(3-Chlorophenyl)-3,4,5,5-tetramethylmorp...)
Affinity DataIC50:  1.60E+4nMAssay Description:Antagonist activity at human alpha4beta2 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322531((2R,3R)-2-(3-Chlorophenyl)-3,5,5-trimethylmorpholi...)
Affinity DataIC50:  1.70E+4nMAssay Description:Antagonist activity at human alpha4beta2 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50322532((2S,3S)-2-(3-Chlorophenyl)-3,5,5-trimethylmorpholi...)
Affinity DataIC50:  2.00E+4nMAssay Description:Antagonist activity at human alpha4beta2 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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