Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50034140
LigandChemical structure of BindingDB Monomer ID 31592BDBM31592(PF-2545920 | substituted pyrazole, 9 | US9138494, ...)
Affinity DataIC50: 0.501nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50419436BDBM50419436(CHEMBL1915747 | US9138494, JNJ-41510417)
Affinity DataIC50: 0.501nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50357701BDBM50357701(CHEMBL1915725 | US9138494, Janssen B-3)
Affinity DataIC50: 1.58nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50419439BDBM50419439(CHEMBL1915727)
Affinity DataIC50: 2.51nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50419437BDBM50419437(CHEMBL1915742)
Affinity DataIC50: 3.16nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50357702BDBM50357702(CHEMBL1915726)
Affinity DataIC50: 3.16nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50419442BDBM50419442(CHEMBL1915746)
Affinity DataIC50: 3.98nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50419428BDBM50419428(CHEMBL1915736)
Affinity DataIC50: 3.98nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50419423BDBM50419423(CHEMBL1915729)
Affinity DataIC50: 5.01nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50419426BDBM50419426(CHEMBL1915733)
Affinity DataIC50: 5.01nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50419424BDBM50419424(CHEMBL1915730)
Affinity DataIC50: 10nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50419430BDBM50419430(CHEMBL1915738)
Affinity DataIC50: 10nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50419440BDBM50419440(CHEMBL1915734)
Affinity DataIC50: 12.6nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50419427BDBM50419427(CHEMBL1915735)
Affinity DataIC50: 15.8nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50419429BDBM50419429(CHEMBL1915737)
Affinity DataIC50: 15.8nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50419433BDBM50419433(CHEMBL1915743)
Affinity DataIC50: 19.9nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50419422BDBM50419422(CHEMBL1915728)
Affinity DataIC50: 19.9nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50419434BDBM50419434(CHEMBL1915744)
Affinity DataIC50: 31.6nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50419435BDBM50419435(CHEMBL1915745)
Affinity DataIC50: 31.6nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50419432BDBM50419432(CHEMBL1915741)
Affinity DataIC50: 31.6nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50419438BDBM50419438(CHEMBL1915732)
Affinity DataIC50: 31.6nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50419431BDBM50419431(CHEMBL1915739)
Affinity DataIC50: 79.4nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50419441BDBM50419441(CHEMBL1915740)
Affinity DataIC50: 100nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50419425BDBM50419425(CHEMBL1915731)
Affinity DataIC50: 100nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357702BDBM50357702(CHEMBL1915726)
Affinity DataIC50: 870nMAssay Description:Inhibition of human DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357701BDBM50357701(CHEMBL1915725 | US9138494, Janssen B-3)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed