Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50000221
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242699BDBM50242699(CHEMBL4060511)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human full length GST tagged IRAK4 expressed in baculovirus infected Sf9 cells using RP7030 peptide as substrate after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242698BDBM50242698(CHEMBL4069200 | US9932350, 3-54)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human full length GST tagged IRAK4 expressed in baculovirus infected Sf9 cells using RP7030 peptide as substrate after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242727BDBM50242727(CHEMBL4096446 | US9932350, 3-19)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human full length GST tagged IRAK4 expressed in baculovirus infected Sf9 cells using RP7030 peptide as substrate after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242697BDBM50242697(CHEMBL4070214 | US9932350, 2-7)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human full length GST tagged IRAK4 expressed in baculovirus infected Sf9 cells using RP7030 peptide as substrate after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242696BDBM50242696(CHEMBL4083650 | US9932350, 2-5)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human full length GST tagged IRAK4 expressed in baculovirus infected Sf9 cells using RP7030 peptide as substrate after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242700BDBM50242700(CHEMBL4088745 | US9932350, 3-20)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human full length GST tagged IRAK4 expressed in baculovirus infected Sf9 cells using RP7030 peptide as substrate after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242708BDBM50242708(CHEMBL4101649 | US9926330, 1-6)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human full length GST tagged IRAK4 expressed in baculovirus infected Sf9 cells using RP7030 peptide as substrate after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242695BDBM50242695(CHEMBL4068395 | US9932350, 2-6)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human full length GST tagged IRAK4 expressed in baculovirus infected Sf9 cells using RP7030 peptide as substrate after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242706BDBM50242706(CHEMBL4063472)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human full length GST tagged IRAK4 expressed in baculovirus infected Sf9 cells using RP7030 peptide as substrate after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242701BDBM50242701(CHEMBL4059675 | US9932350, 3-44)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human full length GST tagged IRAK4 expressed in baculovirus infected Sf9 cells using RP7030 peptide as substrate after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242731BDBM50242731(CHEMBL4089544 | US9932350, 2-14)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human full length GST tagged IRAK4 expressed in baculovirus infected Sf9 cells using RP7030 peptide as substrate after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242707BDBM50242707(CHEMBL4099061)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human full length GST tagged IRAK4 expressed in baculovirus infected Sf9 cells using RP7030 peptide as substrate after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242730BDBM50242730(CHEMBL4072093 | US9926330, 4-1)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human full length GST tagged IRAK4 expressed in baculovirus infected Sf9 cells using RP7030 peptide as substrate after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242728BDBM50242728(CHEMBL4087971 | US9932350, 3-30)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human full length GST tagged IRAK4 expressed in baculovirus infected Sf9 cells using RP7030 peptide as substrate after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242725BDBM50242725(CHEMBL4097259 | US9926330, 1-2)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human full length GST tagged IRAK4 expressed in baculovirus infected Sf9 cells using RP7030 peptide as substrate after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242702BDBM50242702(CHEMBL4082572 | US9932350, 1-1)
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human full length GST tagged IRAK4 expressed in baculovirus infected Sf9 cells using RP7030 peptide as substrate after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242694BDBM50242694(CHEMBL4060699 | US9932350, 3-1)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human full length GST tagged IRAK4 expressed in baculovirus infected Sf9 cells using RP7030 peptide as substrate after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242726BDBM50242726(CHEMBL4079234)
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant human full length GST tagged IRAK4 expressed in baculovirus infected Sf9 cells using RP7030 peptide as substrate after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242729BDBM50242729(CHEMBL4090409 | US9932350, 2-4)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human full length GST tagged IRAK4 expressed in baculovirus infected Sf9 cells using RP7030 peptide as substrate after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242703BDBM50242703(CHEMBL4069378 | US9926330, 1-1)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human full length GST tagged IRAK4 expressed in baculovirus infected Sf9 cells using RP7030 peptide as substrate after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242696BDBM50242696(CHEMBL4083650 | US9932350, 2-5)
Affinity DataEC50:  1.70E+3nMAssay Description:Inhibition of IRAK4 in Lewis rat whole blood assessed as reduction in R848-stimulated TNF alpha production after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242697BDBM50242697(CHEMBL4070214 | US9932350, 2-7)
Affinity DataEC50:  2.30E+3nMAssay Description:Inhibition of IRAK4 in Lewis rat whole blood assessed as reduction in R848-stimulated TNF alpha production after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242705BDBM50242705(CHEMBL4091329 | US9932350, 2-3)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of recombinant human full length GST tagged IRAK4 expressed in baculovirus infected Sf9 cells using RP7030 peptide as substrate after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed