Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50017097
TargetToll-like receptor 7(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50330063(1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at TLR7 in human HEK-SEAP reporter cell assessed as NF-kappaB activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50599745(CHEMBL5188189)
Affinity DataEC50:  180nMAssay Description:Agonist activity at TLR7 in human HEK-SEAP reporter cell assessed as NF-kappaB activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 7(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50599744(CHEMBL5190012)
Affinity DataEC50:  210nMAssay Description:Agonist activity at TLR7 in human HEK-SEAP reporter cell assessed as NF-kappaB activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 8(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50330063(1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c...)
Affinity DataEC50:  800nMAssay Description:Agonist activity at TLR8 in human HEK-SEAP reporter cell assessed as NF-kappaB activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50599743(CHEMBL5202177)
Affinity DataEC50:  990nMAssay Description:Agonist activity at TLR7 in human HEK-SEAP reporter cell assessed as NF-kappaB activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 8(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50599743(CHEMBL5202177)
Affinity DataEC50:  1.84E+3nMAssay Description:Agonist activity at TLR8 in human HEK-SEAP reporter cell assessed as NF-kappaB activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 8(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50599746(CHEMBL5190220)
Affinity DataIC50: 2.19E+3nMAssay Description:Antagonist activity at TLR8 in human HEK-SEAP reporter cell assessed as inhibition of methyl 4-amino-1-(4-(aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 7(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50599742(CHEMBL5202791)
Affinity DataEC50:  3.68E+3nMAssay Description:Agonist activity at TLR7 in human HEK-SEAP reporter cell assessed as NF-kappaB activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 7(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50599746(CHEMBL5190220)
Affinity DataIC50: 3.91E+3nMAssay Description:Antagonist activity at TLR7 in human HEK-SEAP reporter cell assessed as inhibition of methyl 4-amino-1-(4-(aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 7(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50599747(CHEMBL5191902)
Affinity DataIC50: 4.10E+3nMAssay Description:Antagonist activity at TLR7 in human HEK-SEAP reporter cell assessed as inhibition of methyl 4-amino-1-(4-(aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 8(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50599747(CHEMBL5191902)
Affinity DataIC50: 4.41E+3nMAssay Description:Antagonist activity at TLR8 in human HEK-SEAP reporter cell assessed as inhibition of methyl 4-amino-1-(4-(aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 7(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50599741(CHEMBL5195281)
Affinity DataEC50:  1.32E+4nMAssay Description:Agonist activity at TLR7 in human HEK-SEAP reporter cell assessed as NF-kappaB activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 8(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50599741(CHEMBL5195281)
Affinity DataEC50:  1.88E+4nMAssay Description:Agonist activity at TLR8 in human HEK-SEAP reporter cell assessed as NF-kappaB activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 8(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50599742(CHEMBL5202791)
Affinity DataEC50:  2.70E+4nMAssay Description:Agonist activity at TLR8 in human HEK-SEAP reporter cell assessed as NF-kappaB activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 7(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50599740(CHEMBL5173998)
Affinity DataEC50:  2.92E+4nMAssay Description:Agonist activity at TLR7 in human HEK-SEAP reporter cell assessed as NF-kappaB activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed