Compile Data Set for Download or QSAR
Report error Found 51 Enz. Inhib. hit(s) with all data for entry = 50016453
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595087(CHEMBL5192844)
Affinity DataIC50: 100nMAssay Description:Inhibition of human SIRT3 (118 to 399 aa) expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595086(CHEMBL5177283)
Affinity DataIC50: 110nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595088(CHEMBL5201717)
Affinity DataIC50: 120nMAssay Description:Inhibition of human SIRT3 (118 to 399 aa) expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595091(CHEMBL5195052)
Affinity DataIC50: 170nMAssay Description:Inhibition of human SIRT3 (118 to 399 aa) expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595092(CHEMBL5182719)
Affinity DataIC50: 170nMAssay Description:Inhibition of human SIRT3 (118 to 399 aa) expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595089(CHEMBL5192524)
Affinity DataIC50: 210nMAssay Description:Inhibition of human SIRT3 (118 to 399 aa) expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540057(CHEMBL4636862)
Affinity DataIC50: 300nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595085(CHEMBL5197912)
Affinity DataIC50: 300nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595092(CHEMBL5182719)
Affinity DataIC50: 370nMAssay Description:Inhibition of human N-terminal His6 tagged SIRT1 (183-505-(GGGS)2-641-665 residues) expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595088(CHEMBL5201717)
Affinity DataIC50: 390nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595087(CHEMBL5192844)
Affinity DataIC50: 420nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595090(CHEMBL5199223)
Affinity DataIC50: 430nMAssay Description:Inhibition of human SIRT3 (118 to 399 aa) expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595076(CHEMBL5209009)
Affinity DataIC50: 450nMAssay Description:Inhibition of GST-tagged SIRT5 (unknown origin) incubated for 10 mins by HPLC based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595092(CHEMBL5182719)
Affinity DataIC50: 450nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595091(CHEMBL5195052)
Affinity DataIC50: 500nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595088(CHEMBL5201717)
Affinity DataIC50: 540nMAssay Description:Inhibition of human N-terminal His6 tagged SIRT1 (183-505-(GGGS)2-641-665 residues) expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595089(CHEMBL5192524)
Affinity DataIC50: 610nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595089(CHEMBL5192524)
Affinity DataIC50: 610nMAssay Description:Inhibition of human N-terminal His6 tagged SIRT1 (183-505-(GGGS)2-641-665 residues) expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595091(CHEMBL5195052)
Affinity DataIC50: 720nMAssay Description:Inhibition of human N-terminal His6 tagged SIRT1 (183-505-(GGGS)2-641-665 residues) expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595087(CHEMBL5192844)
Affinity DataIC50: 790nMAssay Description:Inhibition of human N-terminal His6 tagged SIRT1 (183-505-(GGGS)2-641-665 residues) expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595077(CHEMBL5197726)
Affinity DataIC50: 890nMAssay Description:Inhibition of GST-tagged SIRT5 (unknown origin) incubated for 10 mins by HPLC based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595090(CHEMBL5199223)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595090(CHEMBL5199223)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of human N-terminal His6 tagged SIRT1 (183-505-(GGGS)2-641-665 residues) expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595083(CHEMBL5184731)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595084(CHEMBL5189634)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595079(CHEMBL4287527)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50255722(CHEMBL4063885)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of GST-tagged SIRT5 (unknown origin) incubated for 10 mins by HPLC based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50255729(CHEMBL4072635)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human recombinant SIRT5 using Benzyl-Lys(succinyl)-AMC as substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595093(CHEMBL5195473)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of GST-tagged SIRT5 (unknown origin) incubated for 5 mins by HPLC based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595082(CHEMBL5182081)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574074(CHEMBL4864451)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of GST-tagged SIRT5 (unknown origin) incubated for 5 mins by HPLC based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595080(CHEMBL5200965)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595096(CHEMBL5186678)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human recombinant SIRT5 using Benzyl-Lys(succinyl)-AMC as substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595095(CHEMBL5190611)
Affinity DataIC50: 9.26E+3nMAssay Description:Inhibition of human recombinant SIRT5 using Benzyl-Lys(succinyl)-AMC as substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595081(CHEMBL5205309)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595072(CHEMBL5202152)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of GST-tagged SIRT5 (unknown origin) incubated for 10 mins by HPLC based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595074(CHEMBL5197331)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of GST-tagged SIRT5 (unknown origin) incubated for 10 mins by HPLC based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595073(CHEMBL5201764)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of GST-tagged SIRT5 (unknown origin) incubated for 10 mins by HPLC based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595075(CHEMBL5198003)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of GST-tagged SIRT5 (unknown origin) incubated for 10 mins by HPLC based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595094(CHEMBL5177660)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of human recombinant SIRT5 using Benzyl-Lys(succinyl)-AMC as substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of recombinant SIRT5 (34 to 302 residues) (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595078(CHEMBL5196002)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595070(CHEMBL5181304)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of GST-tagged SIRT5 (unknown origin) incubated for 10 mins by HPLC based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50235152(CHEBI:4747 | CHEMBL230128)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595071(CHEMBL5186377)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GST-tagged SIRT5 (unknown origin) incubated for 10 mins by HPLC based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346601(Oleanolic acid (OA)(Compound 1) | NSC-114945 | OLE...)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595068(CHEMBL5206776)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GST-tagged SIRT5 (unknown origin) incubated for 10 mins by HPLC based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595069(CHEMBL5205599)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GST-tagged SIRT5 (unknown origin) incubated for 10 mins by HPLC based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595079(CHEMBL4287527)
Affinity DataIC50: 2.56E+5nMAssay Description:Inhibition of SIRT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595079(CHEMBL4287527)
Affinity DataIC50: 2.56E+5nMAssay Description:Inhibition of SIRT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
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