Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50020296
LigandChemical structure of BindingDB Monomer ID 50628608BDBM50628608(CHEMBL5415432)
Affinity DataIC50: 281nMAssay Description:Antagonist activity at human alpha4/beta2 nAChR expressed in HEK293 cells assessed as nicotine-induced intracellular calcium release incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50628605BDBM50628605(CHEMBL5430805)
Affinity DataIC50: 422nMAssay Description:Antagonist activity at human alpha3/beta4 nAChR expressed in HEK293 cells assessed as nicotine-induced intracellular calcium release incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50628604BDBM50628604(CHEMBL5402976)
Affinity DataIC50: 450nMAssay Description:Antagonist activity at human alpha3/beta4 nAChR expressed in HEK293 cells assessed as nicotine-induced intracellular calcium release incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50628612BDBM50628612(CHEMBL5400966)
Affinity DataIC50: 563nMAssay Description:Antagonist activity at human alpha4/beta2 nAChR expressed in HEK293 cells assessed as nicotine-induced intracellular calcium release incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50628606BDBM50628606(CHEMBL5394405)
Affinity DataIC50: 637nMAssay Description:Antagonist activity at human alpha3/beta4 nAChR expressed in HEK293 cells assessed as nicotine-induced intracellular calcium release incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50628611BDBM50628611(CHEMBL5406873)
Affinity DataIC50: 657nMAssay Description:Antagonist activity at human alpha4/beta2 nAChR expressed in HEK293 cells assessed as nicotine-induced intracellular calcium release incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50628602BDBM50628602(CHEMBL5406136)
Affinity DataIC50: 993nMAssay Description:Antagonist activity at human alpha4/beta2 nAChR expressed in HEK293 cells assessed as nicotine-induced intracellular calcium release incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50628603BDBM50628603(CHEMBL5402688)
Affinity DataIC50: 1.04E+3nMAssay Description:Antagonist activity at human alpha4/beta2 nAChR expressed in HEK293 cells assessed as nicotine-induced intracellular calcium release incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50628608BDBM50628608(CHEMBL5415432)
Affinity DataIC50: 1.41E+3nMAssay Description:Antagonist activity at human alpha3/beta4 nAChR expressed in HEK293 cells assessed as nicotine-induced intracellular calcium release incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50628612BDBM50628612(CHEMBL5400966)
Affinity DataIC50: 2.09E+3nMAssay Description:Antagonist activity at human alpha3/beta4 nAChR expressed in HEK293 cells assessed as nicotine-induced intracellular calcium release incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50628607BDBM50628607(CHEMBL5440279)
Affinity DataIC50: 2.45E+3nMAssay Description:Antagonist activity at human alpha3/beta4 nAChR expressed in HEK293 cells assessed as nicotine-induced intracellular calcium release incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50628611BDBM50628611(CHEMBL5406873)
Affinity DataIC50: 2.56E+3nMAssay Description:Antagonist activity at human alpha3/beta4 nAChR expressed in HEK293 cells assessed as nicotine-induced intracellular calcium release incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50628609BDBM50628609(CHEMBL5439646)
Affinity DataIC50: 2.62E+3nMAssay Description:Antagonist activity at human alpha4/beta2 nAChR expressed in HEK293 cells assessed as nicotine-induced intracellular calcium release incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50628606BDBM50628606(CHEMBL5394405)
Affinity DataIC50: 2.82E+3nMAssay Description:Antagonist activity at human alpha4/beta2 nAChR expressed in HEK293 cells assessed as nicotine-induced intracellular calcium release incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50628604BDBM50628604(CHEMBL5402976)
Affinity DataIC50: 3.18E+3nMAssay Description:Antagonist activity at human alpha4/beta2 nAChR expressed in HEK293 cells assessed as nicotine-induced intracellular calcium release incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50628610BDBM50628610(CHEMBL5440486)
Affinity DataIC50: 3.50E+3nMAssay Description:Antagonist activity at human alpha4/beta2 nAChR expressed in HEK293 cells assessed as nicotine-induced intracellular calcium release incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50628605BDBM50628605(CHEMBL5430805)
Affinity DataIC50: 3.73E+3nMAssay Description:Antagonist activity at human alpha4/beta2 nAChR expressed in HEK293 cells assessed as nicotine-induced intracellular calcium release incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50628603BDBM50628603(CHEMBL5402688)
Affinity DataIC50: 4.96E+3nMAssay Description:Antagonist activity at human alpha3/beta4 nAChR expressed in HEK293 cells assessed as nicotine-induced intracellular calcium release incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50628602BDBM50628602(CHEMBL5406136)
Affinity DataIC50: 6.25E+3nMAssay Description:Antagonist activity at human alpha3/beta4 nAChR expressed in HEK293 cells assessed as nicotine-induced intracellular calcium release incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50628607BDBM50628607(CHEMBL5440279)
Affinity DataIC50: 7.72E+3nMAssay Description:Antagonist activity at human alpha4/beta2 nAChR expressed in HEK293 cells assessed as nicotine-induced intracellular calcium release incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50628609BDBM50628609(CHEMBL5439646)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human alpha3/beta4 nAChR expressed in HEK293 cells assessed as nicotine-induced intracellular calcium release incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50628610BDBM50628610(CHEMBL5440486)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human alpha3/beta4 nAChR expressed in HEK293 cells assessed as nicotine-induced intracellular calcium release incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50628611BDBM50628611(CHEMBL5406873)
Affinity DataIC50: 4.47E+4nMAssay Description:Binding affinity to human NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed