Compile Data Set for Download or QSAR
Report error Found 56 Enz. Inhib. hit(s) with all data for entry = 50021143
LigandPNGBDBM50637377(CHEMBL5558206)
Affinity DataIC50: 0.650nMAssay Description:Inhibition of human MMP-2 using 7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)-Ala-Arg-NH2 as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCollagenase 3(Human)TBA
LigandPNGBDBM50637380(CHEMBL5559593)
Affinity DataIC50: 0.650nMAssay Description:Inhibition of C-terminal 6xHis-tagged recombinant MMP-13 (104 to 274 residues) (unknown origin) expressed in Escherichia coli BL21-DE3 pLys S cells u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCollagenase 3(Human)TBA
LigandPNGBDBM50265079(CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...)
Affinity DataIC50: 0.670nMAssay Description:Inhibition of recombinant human MMP13 catalytic domain (Tyr104 to Asp270 residues) using acetyl-Pro-Leu-Gly-[2-mercapto-4-methyl-pentanoyl]-Leu-Gly-O...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50637377(CHEMBL5558206)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human MMP-9 using 7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)-Ala-Arg-NH2 as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50637376(CHEMBL5568549)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human MMP-2 using 7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)-Ala-Arg-NH2 as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50637371(CHEMBL5567551)
Affinity DataIC50: 2nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50637376(CHEMBL5568549)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human MMP-12 using 7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)-Ala-Arg-NH2 as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50637376(CHEMBL5568549)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human MMP-9 using 7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)-Ala-Arg-NH2 as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCollagenase 3(Human)TBA
LigandPNGBDBM50637381(CHEMBL5561714)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of C-terminal 6xHis-tagged recombinant MMP-13 (104 to 274 residues) (unknown origin) expressed in Escherichia coli BL21-DE3 pLys S cells u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50637377(CHEMBL5558206)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human MMP-12 using 7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)-Ala-Arg-NH2 as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCollagenase 3(Human)TBA
LigandPNGBDBM50637378(CHEMBL5560585)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human recombinant MMP-13 using Ac-PLG-[2-mercapto-4-methyl pentanoyl]-LG-OC2H5 as chromogenic substrate measured every 1 min for 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50637371(CHEMBL5567551)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCollagenase 3(Human)TBA
LigandPNGBDBM50637379(CHEMBL5550032)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of human recombinant MMP-13 using Ac-PLG-[2-mercapto-4-methyl pentanoyl]-LG-OC2H5 as chromogenic substrate measured every 1 min for 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCollagenase 3(Human)TBA
LigandPNGBDBM50176995(CHEMBL3814018)
Affinity DataIC50: 6nMAssay Description:Inhibition of MMP-13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCollagenase 3(Human)TBA
LigandPNGBDBM50610752(CHEMBL5268707)
Affinity DataIC50: 6nMAssay Description:Inhibition of MMP-13 (unknown origin) using 5-FAM/QXLTM peptide as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCollagenase 3(Human)TBA
LigandPNGBDBM50637382(CHEMBL5542687)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of C-terminal 6xHis-tagged recombinant MMP-13 (104 to 274 residues) (unknown origin) expressed in Escherichia coli BL21-DE3 pLys S cells u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCollagenase 3(Human)TBA
LigandPNGBDBM50637384(CHEMBL5517807)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of C-terminal 6xHis-tagged recombinant MMP-13 (104 to 274 residues) (unknown origin) expressed in Escherichia coli BL21-DE3 pLys S cells u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCollagenase 3(Human)TBA
LigandPNGBDBM50637375(CHEMBL5560900)
Affinity DataIC50: 10nMAssay Description:Inhibition of MMP-13 (unknown origin) using 5-FAM/QXLTM peptide as substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCollagenase 3(Human)TBA
LigandPNGBDBM50637383(CHEMBL5564283)
Affinity DataIC50: 15nMAssay Description:Inhibition of C-terminal 6xHis-tagged recombinant MMP-13 (104 to 274 residues) (unknown origin) expressed in Escherichia coli BL21-DE3 pLys S cells u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetStromelysin-2(Human)TBA
LigandPNGBDBM50637368(CHEMBL5556387)
Affinity DataIC50: 24nMAssay Description:Inhibition of MMP-10 (unknown origin) using 5-FAM-Pro-Leu-OH as substrate by fluorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCollagenase 3(Human)TBA
LigandPNGBDBM50234334(benzyl 6-benzyl-5,7-dioxo-6,7-dihydro-5H-thiazolo[...)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human MMP13 catalytic domain (Tyr104 to Asp270 residues) using acetyl-Pro-Leu-Gly-[2-mercapto-4-methyl-pentanoyl]-Leu-Gly-O...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCollagenase 3(Human)TBA
LigandPNGBDBM50637374(CHEMBL5566293)
Affinity DataIC50: 35nMAssay Description:Inhibition of MMP-13 (unknown origin) using 5-FAM/QXLTM peptide as substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50637362(CHEMBL5566078)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant MMP-2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50637364(CHEMBL5558542)
Affinity DataIC50: 40nMAssay Description:Inhibition of MMP-9 catalytic domain (unknown origin) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate measured for 3 mins by fluorimetric assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetStromelysin-2(Human)TBA
LigandPNGBDBM50637366(CHEMBL5562384)
Affinity DataIC50: 53nMAssay Description:Inhibition of MMP-10 (unknown origin) using 5-FAM-Pro-Leu-OH as substrate by fluorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM13080(N-hydroxy-2-[(4-methoxybenzene)(2-methylpropyl)sul...)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant MMP-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50637363(CHEMBL5555989)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant MMP-2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50146816((cyclopentylamino)carbonylphosphonic acid | CHEMBL...)
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant MMP-2 (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50405547(CHEMBL5291044)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant MMP-9 using Ac-PLG-[2-mercapto-4-methyl pentanoyl]-LG-OC2H5 as chromogenic substrate incubated for 60 mins by colorim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50146800((cyclobutylamino)carbonylphosphonic acid | CHEMBL9...)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant MMP-2 (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50637365(CHEMBL5560685)
Affinity DataIC50: 300nMAssay Description:Inhibition of MMP-9 catalytic domain (unknown origin) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate measured for 3 mins by fluorimetric assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM170126(4-(3-(4-Phenyl ethyl oxygen)-5-(2-hydroxyphenyl)-4...)
Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant human MMP-2 incubated for 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCollagenase 3(Human)TBA
LigandPNGBDBM50637366(CHEMBL5562384)
Affinity DataIC50: 354nMAssay Description:Inhibition of human recombinant MMP-13 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate by fluorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50405537(CHEMBL5269640)
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant MMP-2 using Ac-PLG-[2-mercapto-4-methyl pentanoyl]-LG-OC2H5 as chromogenic substrate incubated for 60 mins by colorim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50405537(CHEMBL5269640)
Affinity DataIC50: 390nMAssay Description:Inhibition of human recombinant MMP-9 using Ac-PLG-[2-mercapto-4-methyl pentanoyl]-LG-OC2H5 as chromogenic substrate incubated for 60 mins by colorim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCollagenase 3(Human)TBA
LigandPNGBDBM50637368(CHEMBL5556387)
Affinity DataIC50: 460nMAssay Description:Inhibition of human recombinant MMP-13 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate by fluorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50405547(CHEMBL5291044)
Affinity DataIC50: 470nMAssay Description:Inhibition of human recombinant MMP-2 using Ac-PLG-[2-mercapto-4-methyl pentanoyl]-LG-OC2H5 as chromogenic substrate incubated for 60 mins by colorim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50637372(CHEMBL5560889)
Affinity DataIC50: 700nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50637372(CHEMBL5560889)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetStromelysin-2(Human)TBA
LigandPNGBDBM50637367(CHEMBL5568159)
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of MMP-10 (unknown origin) using 5-FAM-Pro-Leu-OH as substrate by fluorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCollagenase 3(Human)TBA
LigandPNGBDBM50233887(CHEMBL1511860)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of recombinant MMP-13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50637361(CHEMBL1205446)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant MMP-2 (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50146801((cyclohexylamino)carbonylphosphonic acid | CHEMBL3...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant MMP-2 (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50146808([(1-ethylpropyl)amino]carbonylphosphonic acid | CH...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant MMP-2 (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50146817((sec-butylamino)carbonylphosphonic acid | CHEMBL97...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant MMP-2 (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCollagenase 3(Human)TBA
LigandPNGBDBM50637367(CHEMBL5568159)
Affinity DataIC50: 7.77E+3nMAssay Description:Inhibition of human recombinant MMP-13 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate by fluorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetInterstitial collagenase(Human)TBA
LigandPNGBDBM50070942((-)-Epigallocatechin-3-o-gallate | (-)-Epigallocat...)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of MMP-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetStromelysin-2(Human)TBA
LigandPNGBDBM50176995(CHEMBL3814018)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of MMP-10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50637369(CHEMBL5542686)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetInterstitial collagenase(Human)TBA
LigandPNGBDBM50637387(CHEMBL5565553)
Affinity DataIC50: 9.75E+3nMAssay Description:Inhibition of MMP-1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
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