Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50021568
TargetPoly [ADP-ribose] polymerase 1(Human)
Yixing People's Hospital Yixing

Curated by ChEMBL
LigandPNGBDBM50084621(BMN 673 | Talazoparib | US12427157, Example R8H-15)
Affinity DataIC50: 0.570nMAssay Description:Inhibition of recombinant human PARP1 using HRP as substrate by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Yixing People's Hospital Yixing

Curated by ChEMBL
LigandPNGBDBM50145143(CHEMBL3765528)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant human PARP1 using HRP as substrate by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Yixing People's Hospital Yixing

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of recombinant human PARP1 using HRP as substrate by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Yixing People's Hospital Yixing

Curated by ChEMBL
LigandPNGBDBM50446130(AG-014699 | AG-14447 | Rucaparib | RUCAPARIB CAMSY...)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human PARP1 using HRP as substrate by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Yixing People's Hospital Yixing

Curated by ChEMBL
LigandPNGBDBM209932(Veliparib | 2-[(2R)-2-methylpyrrolidin-2-yl]-1H-be...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of recombinant human PARP1 using HRP as substrate by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Yixing People's Hospital Yixing

Curated by ChEMBL
LigandPNGBDBM50145156(CHEMBL3764816)
Affinity DataIC50: 144nMAssay Description:Inhibition of recombinant human PARP1 using HRP as substrate by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed