Compile Data Set for Download or QSAR
maximum 50k data
Found 41 Enz. Inhib. hit(s) with all data for entry = 50001278
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50006689((S)-2-(2-fluoro-4-(((2-methyl-4-oxo-3,4-dihydroqui...)
Affinity DataIC50:  20nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50006687((S)-2-(4-(((2-methyl-4-oxo-3,4-dihydroquinazolin-6...)
Affinity DataIC50:  40nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014501((S)-2-(2-fluoro-4-((2-fluoroethyl)((2-methyl-4-oxo...)
Affinity DataIC50:  43nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014506((S)-2-(4-(ethyl((2-methyl-4-oxo-3,4-dihydroquinazo...)
Affinity DataIC50:  45nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014518((S)-2-(2-methoxy-4-(((2-methyl-4-oxo-3,4-dihydroqu...)
Affinity DataIC50:  67nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014514((S)-2-(2-chloro-4-(((2-methyl-4-oxo-3,4-dihydroqui...)
Affinity DataIC50:  74nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014516((S)-2-(4-(allyl((2-methyl-4-oxo-3,4-dihydroquinazo...)
Affinity DataIC50:  76nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014505((S)-2-(2-fluoro-4-((2-hydroxyethyl)((2-methyl-4-ox...)
Affinity DataIC50:  78nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014527((S)-2-(2-hydroxy-4-(((2-methyl-4-oxo-3,4-dihydroqu...)
Affinity DataIC50:  90nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014517((S)-2-(2-chloro-4-(ethyl((2-methyl-4-oxo-3,4-dihyd...)
Affinity DataIC50:  120nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50006694((S)-2-(2-fluoro-4-(methyl((2-methyl-4-oxo-3,4-dihy...)
Affinity DataIC50:  120nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014509((S)-2-(4-(((2-methyl-4-oxo-3,4-dihydroquinazolin-6...)
Affinity DataIC50:  130nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014500((S)-2-(4-(ethyl((2-methyl-4-oxo-3,4-dihydroquinazo...)
Affinity DataIC50:  145nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012045((S)-2-(4-(ethyl((2-methyl-4-oxo-3,4-dihydroquinazo...)
Affinity DataIC50:  170nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014504((S)-2-(4-((cyanomethyl)((2-methyl-4-oxo-3,4-dihydr...)
Affinity DataIC50:  170nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014520((S)-2-(4-(ethyl((2-methyl-4-oxo-3,4-dihydroquinazo...)
Affinity DataIC50:  190nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014473((S)-2-(4-((2-fluoroethyl)((2-methyl-4-oxo-3,4-dihy...)
Affinity DataIC50:  240nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014507((S)-2-(2-amino-4-(((2-methyl-4-oxo-3,4-dihydroquin...)
Affinity DataIC50:  290nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50006691((S)-2-(4-(methyl((2-methyl-4-oxo-3,4-dihydroquinaz...)
Affinity DataIC50:  300nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014499((S)-2-(2-amino-4-(ethyl((2-methyl-4-oxo-3,4-dihydr...)
Affinity DataIC50:  310nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014524((S)-2-(4-(ethyl((2-methyl-4-oxo-3,4-dihydroquinazo...)
Affinity DataIC50:  320nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014522((S)-2-(4-(((2-methyl-4-oxo-3,4-dihydroquinazolin-6...)
Affinity DataIC50:  480nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014481((S)-2-(4-(allyl((2-methyl-4-oxo-3,4-dihydroquinazo...)
Affinity DataIC50:  480nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014526((S)-2-(2-methyl-4-(((2-methyl-4-oxo-3,4-dihydroqui...)
Affinity DataIC50:  500nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014486((S)-2-(4-((2-hydroxyethyl)((2-methyl-4-oxo-3,4-dih...)
Affinity DataIC50:  500nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014469((S)-2-(4-((3-hydroxypropyl)((2-methyl-4-oxo-3,4-di...)
Affinity DataIC50:  540nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014512((S)-2-(2-fluoro-4-((3-hydroxypropyl)((2-methyl-4-o...)
Affinity DataIC50:  590nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014503((S)-2-(4-(ethyl((2-methyl-4-oxo-3,4-dihydroquinazo...)
Affinity DataIC50:  680nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014502((S)-2-(2-amino-4-(methyl((2-methyl-4-oxo-3,4-dihyd...)
Affinity DataIC50:  860nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014521((S)-2-(2-methyl-4-(methyl((2-methyl-4-oxo-3,4-dihy...)
Affinity DataIC50:  940nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014510((S)-2-(3-fluoro-4-((3-hydroxypropyl)((2-methyl-4-o...)
Affinity DataIC50:  980nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50006690((S)-2-(3-fluoro-4-(methyl((2-methyl-4-oxo-3,4-dihy...)
Affinity DataIC50:  1.14E+3nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014525((S)-2-(4-((2-amino-2-oxoethyl)((2-methyl-4-oxo-3,4...)
Affinity DataIC50:  1.34E+3nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50006684((S)-2-(3-fluoro-4-(((2-methyl-4-oxo-3,4-dihydroqui...)
Affinity DataIC50:  1.43E+3nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014519((S)-2-(3-fluoro-4-((2-fluoroethyl)((2-methyl-4-oxo...)
Affinity DataIC50:  1.75E+3nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014508((S)-2-(3-fluoro-4-((2-hydroxyethyl)((2-methyl-4-ox...)
Affinity DataIC50:  3.58E+3nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014513((S)-2-(2-fluoro-4-((2-methyl-4-oxo-3,4-dihydroquin...)
Affinity DataIC50:  3.78E+3nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012516((S)-2-(4-((2-methyl-4-oxo-3,4-dihydroquinazolin-6-...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014515((S)-2-(4-(allyl((2-methyl-4-oxo-3,4-dihydroquinazo...)
Affinity DataIC50:  5.16E+3nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014523((S)-2-(3-fluoro-4-((2-methyl-4-oxo-3,4-dihydroquin...)
Affinity DataIC50:  9.34E+3nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014511((S)-2-(4-((2-aminoethyl)((2-methyl-4-oxo-3,4-dihyd...)
Affinity DataIC50:  1.17E+4nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed