Compile Data Set for Download or QSAR
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Found 16 Enz. Inhib. hit(s) with all data for entry = 50011104
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102319(11-(4-Methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thia...)
Affinity DataIC50:  49nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102318(2-{2-[4-(5,5-Dioxo-5H-5lambda*6*-dibenzo[b,f][1,4]...)
Affinity DataIC50:  132nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataIC50:  132nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102320(11-{4-[2-(2-Hydroxy-ethoxy)-ethyl]-piperazin-1-yl}...)
Affinity DataIC50:  166nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102326(11-[4-(3,4-Dimethoxy-butyl)-piperazin-1-yl]-dibenz...)
Affinity DataIC50:  293nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095890(2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperaz...)
Affinity DataIC50:  330nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102321(11-[4-(Tetrahydro-furan-2-ylmethyl)-piperazin-1-yl...)
Affinity DataIC50:  417nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102323(2-{2-[4-(7-Fluoro-dibenzo[b,f][1,4]thiazepin-11-yl...)
Affinity DataIC50:  560nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102314(3-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-...)
Affinity DataIC50:  755nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102322(11-[4-(2,3-Dimethoxy-propyl)-piperazin-1-yl]-diben...)
Affinity DataIC50:  795nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102324(7-Fluoro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f]...)
Affinity DataIC50:  963nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102327(2-{2-[4-(3-Chloro-11H-dibenzo[b,e]azepin-6-yl)-pip...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102315(2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-...)
Affinity DataIC50:  1.33E+3nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102316(2-{2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-pipera...)
Affinity DataIC50:  1.39E+3nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102317(2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-...)
Affinity DataIC50:  1.64E+3nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102325(6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepin...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed