Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with all data for entry = 50012254
TargetDNA repair endonuclease XPF(Homo sapiens)
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50555906(CHEMBL4759590)
Affinity DataIC50:  490nMAssay Description:Inhibition of human His-tagged human ERCC1-XPF expressed in Escherichia coli BL21 (DE3) cells using 6-FAM-5'CAGCGCTCGG(20T)CCGAGCGCTG-3'-dabcyl measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair endonuclease XPF(Homo sapiens)
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM81244(4-[(6-chloranyl-2-methoxy-acridin-9-yl)amino]-2-[(...)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibition of human His-tagged human ERCC1-XPF expressed in Escherichia coli BL21 (DE3) cells using 6-FAM-5'CAGCGCTCGG(20T)CCGAGCGCTG-3'-dabcyl measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair endonuclease XPF(Homo sapiens)
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50555906(CHEMBL4759590)
Affinity DataKd:  85nMAssay Description:Binding affinity to His-tagged human ERCC1-XPF expressed in Escherichia coli BL21 (DE3) cells by steady-state fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair endonuclease XPF(Homo sapiens)
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM81244(4-[(6-chloranyl-2-methoxy-acridin-9-yl)amino]-2-[(...)
Affinity DataKd:  140nMAssay Description:Binding affinity to His-tagged human ERCC1-XPF expressed in Escherichia coli BL21 (DE3) cells by steady-state fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed