Compile Data Set for Download or QSAR
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Found 27 Enz. Inhib. hit(s) with all data for entry = 50030012
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50073429(CHEMBL82032 | CHEMBL84575 | N-((S)-1-Carbamimidoyl...)
Affinity DataIC50:  0.710nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor IIMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50081158(2-((R)-3-Amino-3-benzyl-2-oxo-piperidin-1-yl)-N-((...)
Affinity DataIC50:  2.10nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor IIMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50071693(CHEMBL38927 | CVS-1578 | N-((S)-1-Carbamimidoyl-2-...)
Affinity DataIC50:  6.20nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor IIMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290248(2-((R)-3-Amino-3-benzyl-2-oxo-azepan-1-yl)-N-((S)-...)
Affinity DataIC50:  15nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor IIMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50073429(CHEMBL82032 | CHEMBL84575 | N-((S)-1-Carbamimidoyl...)
Affinity DataIC50:  23nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290242(2-(3-Benzyl-3-methanesulfonylamino-2-oxo-piperidin...)
Affinity DataIC50:  32nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor IIMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290242(2-(3-Benzyl-3-methanesulfonylamino-2-oxo-piperidin...)
Affinity DataIC50:  52nMAssay Description:The compound was tested in vitro for inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290243(CHEMBL431782 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  125nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor IIMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290244(2-((S)-3-Amino-3-benzyl-2-oxo-piperidin-1-yl)-N-((...)
Affinity DataIC50:  138nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor IIMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50081158(2-((R)-3-Amino-3-benzyl-2-oxo-piperidin-1-yl)-N-((...)
Affinity DataIC50:  139nMAssay Description:The compound was tested in vitro for inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50073429(CHEMBL82032 | CHEMBL84575 | N-((S)-1-Carbamimidoyl...)
Affinity DataIC50:  152nMAssay Description:The compound was tested in vitro for inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290249(2-((S)-3-Amino-3-benzyl-2-oxo-azepan-1-yl)-N-((S)-...)
Affinity DataIC50:  193nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor IIMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290246(CHEMBL80128 | {3-Benzyl-1-[((S)-1-carbamimidoyl-2-...)
Affinity DataIC50:  466nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor IIMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290243(CHEMBL431782 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  538nMAssay Description:The compound was tested in vitro for inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290248(2-((R)-3-Amino-3-benzyl-2-oxo-azepan-1-yl)-N-((S)-...)
Affinity DataIC50:  969nMAssay Description:The compound was tested in vitro for inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50071693(CHEMBL38927 | CVS-1578 | N-((S)-1-Carbamimidoyl-2-...)
Affinity DataIC50:  1.27E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290245(2-((S)-3-Amino-3-benzyl-2-oxo-pyrrolidin-1-yl)-N-(...)
Affinity DataIC50:  1.38E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor IIMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290245(2-((S)-3-Amino-3-benzyl-2-oxo-pyrrolidin-1-yl)-N-(...)
Affinity DataIC50:  1.38E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290246(CHEMBL80128 | {3-Benzyl-1-[((S)-1-carbamimidoyl-2-...)
Affinity DataIC50:  2.50E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290248(2-((R)-3-Amino-3-benzyl-2-oxo-azepan-1-yl)-N-((S)-...)
Affinity DataIC50: >2.50E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290243(CHEMBL431782 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50: >2.50E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290244(2-((S)-3-Amino-3-benzyl-2-oxo-piperidin-1-yl)-N-((...)
Affinity DataIC50:  2.50E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290249(2-((S)-3-Amino-3-benzyl-2-oxo-azepan-1-yl)-N-((S)-...)
Affinity DataIC50:  2.50E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290246(CHEMBL80128 | {3-Benzyl-1-[((S)-1-carbamimidoyl-2-...)
Affinity DataIC50:  2.50E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290242(2-(3-Benzyl-3-methanesulfonylamino-2-oxo-piperidin...)
Affinity DataIC50: >2.50E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50071693(CHEMBL38927 | CVS-1578 | N-((S)-1-Carbamimidoyl-2-...)
Affinity DataIC50: >2.50E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290245(2-((S)-3-Amino-3-benzyl-2-oxo-pyrrolidin-1-yl)-N-(...)
Affinity DataIC50:  2.50E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails Article