Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50030012
TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50073429(CHEMBL84575 | CHEMBL82032 | N-((S)-1-Carbamimidoyl...)
Affinity DataIC50: 0.710nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081158(CHEMBL79422 | CHEMBL314914 | 2-((R)-3-Amino-3-benz...)
Affinity DataIC50: 2.10nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50071693(N-((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-yl)-2...)
Affinity DataIC50: 6.20nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290248(2-((R)-3-Amino-3-benzyl-2-oxo-azepan-1-yl)-N-((S)-...)
Affinity DataIC50: 15nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetCoagulation factor X(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50073429(CHEMBL84575 | CHEMBL82032 | N-((S)-1-Carbamimidoyl...)
Affinity DataIC50: 23nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290242(2-(3-Benzyl-3-methanesulfonylamino-2-oxo-piperidin...)
Affinity DataIC50: 32nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290242(2-(3-Benzyl-3-methanesulfonylamino-2-oxo-piperidin...)
Affinity DataIC50: 52nMAssay Description:The compound was tested in vitro for inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290243(N-((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-yl)-2...)
Affinity DataIC50: 125nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290244(2-((S)-3-Amino-3-benzyl-2-oxo-piperidin-1-yl)-N-((...)
Affinity DataIC50: 138nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081158(CHEMBL79422 | CHEMBL314914 | 2-((R)-3-Amino-3-benz...)
Affinity DataIC50: 139nMAssay Description:The compound was tested in vitro for inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50073429(CHEMBL84575 | CHEMBL82032 | N-((S)-1-Carbamimidoyl...)
Affinity DataIC50: 152nMAssay Description:The compound was tested in vitro for inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290249(2-((S)-3-Amino-3-benzyl-2-oxo-azepan-1-yl)-N-((S)-...)
Affinity DataIC50: 193nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290246({3-Benzyl-1-[((S)-1-carbamimidoyl-2-hydroxy-piperi...)
Affinity DataIC50: 466nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290243(N-((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-yl)-2...)
Affinity DataIC50: 538nMAssay Description:The compound was tested in vitro for inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290248(2-((R)-3-Amino-3-benzyl-2-oxo-azepan-1-yl)-N-((S)-...)
Affinity DataIC50: 969nMAssay Description:The compound was tested in vitro for inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50071693(N-((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-yl)-2...)
Affinity DataIC50: 1.27E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290245(2-((S)-3-Amino-3-benzyl-2-oxo-pyrrolidin-1-yl)-N-(...)
Affinity DataIC50: 1.38E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290245(2-((S)-3-Amino-3-benzyl-2-oxo-pyrrolidin-1-yl)-N-(...)
Affinity DataIC50: 1.38E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290249(2-((S)-3-Amino-3-benzyl-2-oxo-azepan-1-yl)-N-((S)-...)
Affinity DataIC50: 2.50E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetCoagulation factor X(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290242(2-(3-Benzyl-3-methanesulfonylamino-2-oxo-piperidin...)
Affinity DataIC50: 2.50E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetCoagulation factor X(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50071693(N-((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-yl)-2...)
Affinity DataIC50: 2.50E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetCoagulation factor X(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290246({3-Benzyl-1-[((S)-1-carbamimidoyl-2-hydroxy-piperi...)
Affinity DataIC50: 2.50E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290246({3-Benzyl-1-[((S)-1-carbamimidoyl-2-hydroxy-piperi...)
Affinity DataIC50: 2.50E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetCoagulation factor X(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290245(2-((S)-3-Amino-3-benzyl-2-oxo-pyrrolidin-1-yl)-N-(...)
Affinity DataIC50: 2.50E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290244(2-((S)-3-Amino-3-benzyl-2-oxo-piperidin-1-yl)-N-((...)
Affinity DataIC50: 2.50E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetCoagulation factor X(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290243(N-((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-yl)-2...)
Affinity DataIC50: 2.50E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetCoagulation factor X(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290248(2-((R)-3-Amino-3-benzyl-2-oxo-azepan-1-yl)-N-((S)-...)
Affinity DataIC50: 2.50E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article