Compile Data Set for Download or QSAR
maximum 50k data
Found 24 Enz. Inhib. hit(s) with all data for entry = 50030085
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290981(CHEMBL319452 | PD-163140 | [4-Benzo[1,3]dioxol-5-y...)
Affinity DataIC50:  0.350nMAssay Description:Binding affinity for human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50034267(3-(benzo[d][1,3]dioxol-5-yl)-5-hydroxy-5-(4-methox...)
Affinity DataIC50:  0.370nMAssay Description:Binding affinity for human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290983(3-[4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-5-...)
Affinity DataIC50:  0.400nMAssay Description:Binding affinity for human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290980(2-[4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-5-...)
Affinity DataIC50:  0.5nMAssay Description:Binding affinity for human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290984(2-[4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-5-...)
Affinity DataIC50:  0.600nMAssay Description:Binding affinity for human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290982(Allyl-carbamic acid 4-benzo[1,3]dioxol-5-yl-2-(4-m...)
Affinity DataIC50:  0.800nMAssay Description:Binding affinity for human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290979(((S)-1-Naphthalen-1-yl-ethyl)-carbamic acid 4-benz...)
Affinity DataIC50:  2nMAssay Description:Binding affinity for human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290979(((S)-1-Naphthalen-1-yl-ethyl)-carbamic acid 4-benz...)
Affinity DataIC50:  2nMAssay Description:Binding affinity for human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50057155((Z)-2-Benzo[1,3]dioxol-5-yl-3-benzyl-4-(4-methoxy-...)
Affinity DataIC50:  7.40nMAssay Description:Binding affinity for human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290986(CHEMBL320183 | Methyl-carbamic acid 4-benzo[1,3]di...)
Affinity DataIC50:  9nMAssay Description:Binding affinity for human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290985(((S)-1-Phenyl-ethyl)-carbamic acid 4-benzo[1,3]dio...)
Affinity DataIC50:  18nMAssay Description:Binding affinity for human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50057176(3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-methoxy-5-(4-me...)
Affinity DataIC50:  300nMAssay Description:Binding affinity for human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50034267(3-(benzo[d][1,3]dioxol-5-yl)-5-hydroxy-5-(4-methox...)
Affinity DataIC50:  480nMAssay Description:Binding affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290984(2-[4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-5-...)
Affinity DataIC50:  1.30E+3nMAssay Description:Binding affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290981(CHEMBL319452 | PD-163140 | [4-Benzo[1,3]dioxol-5-y...)
Affinity DataIC50:  1.80E+3nMAssay Description:Binding affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290985(((S)-1-Phenyl-ethyl)-carbamic acid 4-benzo[1,3]dio...)
Affinity DataIC50: >2.50E+3nMAssay Description:Binding affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290982(Allyl-carbamic acid 4-benzo[1,3]dioxol-5-yl-2-(4-m...)
Affinity DataIC50: >2.50E+3nMAssay Description:Binding affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290979(((S)-1-Naphthalen-1-yl-ethyl)-carbamic acid 4-benz...)
Affinity DataIC50: >2.50E+3nMAssay Description:Binding affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290979(((S)-1-Naphthalen-1-yl-ethyl)-carbamic acid 4-benz...)
Affinity DataIC50: >2.50E+3nMAssay Description:Binding affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290980(2-[4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-5-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Binding affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290986(CHEMBL320183 | Methyl-carbamic acid 4-benzo[1,3]di...)
Affinity DataIC50: >2.50E+3nMAssay Description:Binding affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290983(3-[4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-5-...)
Affinity DataIC50: >2.50E+3nMAssay Description:Binding affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50057155((Z)-2-Benzo[1,3]dioxol-5-yl-3-benzyl-4-(4-methoxy-...)
Affinity DataIC50:  4.55E+3nMAssay Description:Binding affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50057176(3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-methoxy-5-(4-me...)
Affinity DataIC50: >2.50E+4nMAssay Description:Binding affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article