Compile Data Set for Download or QSAR
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Found 6 Enz. Inhib. hit(s) with all data for entry = 50033387
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  50nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as conversion of [14C]-arachidonic acid to [14C]-prostaglandins preincubated for 20 mins by thin-laye...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50090808(CHEMBL319825 | [1-(4-Chloro-benzoyl)-5-methoxy-2-m...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human COX2 expressed in SF-9 insect cells assessed as conversion of [14C]-arachidonic acid to [14C]-prostaglandins preincubated for 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  750nMAssay Description:Inhibition of human COX2 expressed in SF-9 insect cells assessed as conversion of [14C]-arachidonic acid to [14C]-prostaglandins preincubated for 20 ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50090808(CHEMBL319825 | [1-(4-Chloro-benzoyl)-5-methoxy-2-m...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as conversion of [14C]-arachidonic acid to [14C]-prostaglandins preincubated for 20 mins by thin-laye...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50344304(2-{1-[(4-Chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of mouse COX2 assessed as conversion of [14C]-arachidonic acid to [14C]-prostaglandins preincubated for 17 mins by thin-layer chromatograp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50344304(2-{1-[(4-Chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of ovine COX1 assessed as conversion of [14C]-arachidonic acid to [14C]-prostaglandins preincubated for 17 mins by thin-layer chromatograp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed