Compile Data Set for Download or QSAR
maximum 50k data
Found 24 Enz. Inhib. hit(s) with all data for entry = 50039014
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303940(2-(Benzylaminocarbonyloxy-)5-O-Salicyloyl-1,4:3,6-...)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303950(CHEMBL583687 | Isosorbide-2-benzylcarbamate-5-(o-t...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253231((3R,3aR,6S,6aR)-6-(benzylcarbamoyloxy)hexahydrofur...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303952(2-(Dimethylaminocarbonyloxy-)5-O-Salicyloyl-1,4:3,...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303951(2-(Ethylaminocarbonyloxy-)5-O-Salicyloyl-1,4:3,6-d...)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253266((3R,3aR,6S,6aR)-6-(benzylcarbamoyloxy)hexahydrofur...)
Affinity DataIC50:  12nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303941(2-(Benzylaminocarbonyloxy-)5-O-(m-hydroxybenzoyl)-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303943(2-(Benzylaminocarbonyloxy-)5-O-(o-nitro-benzoyl)-1...)
Affinity DataIC50:  18nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  19nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303946(2-(benzylaminocarbonyloxy-)5-O-(o-amino-benzoyl)-1...)
Affinity DataIC50:  27nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303944(2-(Benzylaminocarbonyloxy-)5-O-(m-nitro-benzoyl)-1...)
Affinity DataIC50:  32nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM10620((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...)
Affinity DataIC50:  37nMAssay Description:Inhibition of BuChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303949(2-(Benzylaminocarbonyloxy-)5-O-(o-nitroso-benzoyl)...)
Affinity DataIC50:  39nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  53nMAssay Description:Inhibition of electric eel AChE type 6SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253230((3R,3aR,6S,6aR)-6-(benzylcarbamoyloxy)hexahydrofur...)
Affinity DataIC50:  57nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303939((3R,3aR,6S,6aR)-6-(butylcarbamoyloxy)hexahydrofuro...)
Affinity DataIC50:  72nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303947(2-(Benzylaminocarbonyloxy-)5-O-(m-amino-benzoyl)-1...)
Affinity DataIC50:  86nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303945(2-(Benzylaminocarbonyloxy-)5-O-(p-nitro-benzoyl)-1...)
Affinity DataIC50:  117nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303948(2-(Benzylaminocarbonyloxy-)5-O-(p-amino-benzoyl)-1...)
Affinity DataIC50:  297nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303942(2-(Benzylaminocarbonyloxy-)5-O-(p-hydroxy-benzoyl)...)
Affinity DataIC50:  323nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303954(2-(Morpholinocarbonyloxy-)5-O-salicyloyl-1,4:3,6-d...)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303953(2-(Diethylaminocarbonyloxy-)5-O-salicyloyl-1,4:3,6...)
Affinity DataIC50:  2.61E+3nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303940(2-(Benzylaminocarbonyloxy-)5-O-Salicyloyl-1,4:3,6-...)
Affinity DataIC50:  3.42E+3nMAssay Description:Inhibition of human CES2-mediated pNPA substrate turnoverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50252790(CHEMBL524046 | Isosorbide-2-benzylcarbamate | isos...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed