Compile Data Set for Download or QSAR
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Found 19 Enz. Inhib. hit(s) with all data for entry = 50044390
TargetBeta-secretase 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50015538(CHEMBL3265330)
Affinity DataIC50:  20nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as amyloid beta production wild type APP expressing by cell based assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50015546(CHEMBL3265334)
Affinity DataIC50:  60nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50015541(CHEMBL3265331)
Affinity DataIC50:  80nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as amyloid beta production wild type APP expressing by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50015543(CHEMBL3265332)
Affinity DataIC50:  90nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as amyloid beta production wild type APP expressing by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50015538(CHEMBL3265330)
Affinity DataIC50:  110nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50015546(CHEMBL3265334)
Affinity DataIC50:  110nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as amyloid beta production wild type APP expressing by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50015547(CHEMBL3265335)
Affinity DataIC50:  130nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as amyloid beta production wild type APP expressing by cell based assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50015545(CHEMBL3265333)
Affinity DataIC50:  140nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as amyloid beta production wild type APP expressing by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50015541(CHEMBL3265331)
Affinity DataIC50:  150nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50015545(CHEMBL3265333)
Affinity DataIC50:  300nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50015543(CHEMBL3265332)
Affinity DataIC50:  360nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50015560(CHEMBL3265338)
Affinity DataIC50:  420nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50015547(CHEMBL3265335)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50015547(CHEMBL3265335)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50015550(CHEMBL3265337)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50015550(CHEMBL3265337)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50015538(CHEMBL3265330)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50015548(CHEMBL3265336)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50015560(CHEMBL3265338)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed