Compile Data Set for Download or QSAR
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Found 18 Enz. Inhib. hit(s) with all data for entry = 917
TargetProlyl endopeptidase(Homo sapiens (Human))
Universitat De Barcelona

US Patent
LigandPNGBDBM298372((S)-1-((S)-1-(4-(benzyloxy)-3-(trifluoromethyl)ben...)
Affinity DataIC50:  4.5nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetProlyl endopeptidase(Homo sapiens (Human))
Universitat De Barcelona

US Patent
LigandPNGBDBM298373((S)-1-((S)-1-(4-(benzyloxy)-3-fluorobenzoyl)-4,4-d...)
Affinity DataIC50:  5nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Universitat De Barcelona

US Patent
LigandPNGBDBM298357((S)-1-((2S,4S)-1-(4-(benzyloxy)-3,5-dimethoxybenzo...)
Affinity DataIC50:  13.1nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetProlyl endopeptidase(Homo sapiens (Human))
Universitat De Barcelona

US Patent
LigandPNGBDBM298355((S)-1-((2S)-1-(4-(benzyloxy)-3,5-dimethoxybenzoyl)...)
Affinity DataIC50:  48.7nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Universitat De Barcelona

US Patent
LigandPNGBDBM298352((S)-1-((2S,4R)-1-(4-(benzyloxy)-3,5-dimethoxybenzo...)
Affinity DataIC50:  60.4nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Universitat De Barcelona

US Patent
LigandPNGBDBM298345((S)-1-((2S,4R)-1-(4-(benzyloxy)-3,5-dimethoxybenzo...)
Affinity DataIC50:  63.8nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Universitat De Barcelona

US Patent
LigandPNGBDBM298363((S)-1-((2S)-1-(4-benzoyloxy-3,5-dimethoxybenzoyl)-...)
Affinity DataIC50:  111nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Universitat De Barcelona

US Patent
LigandPNGBDBM298359((S)-1-((2S,4S)-1-(4-(benzyloxy)-3,5-dimethoxybenzo...)
Affinity DataIC50:  176nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Universitat De Barcelona

US Patent
LigandPNGBDBM298356((S)-1-((2S,4S)-1-(4-(benzyloxy)-3,5-dimethoxybenzo...)
Affinity DataIC50:  176nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Universitat De Barcelona

US Patent
LigandPNGBDBM298371((S)-1-((S)-1-(2-(benzyloxy)benzoyl)-4,4-difluoropy...)
Affinity DataIC50:  255nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Universitat De Barcelona

US Patent
LigandPNGBDBM298368((S)-1-((S)-1-(4-(benzyloxy)benzoyl)-4,4-difluoropy...)
Affinity DataIC50:  287nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Universitat De Barcelona

US Patent
LigandPNGBDBM298364((S)-1-((2S)-1-(3,4-dibenzyloxy-5-methoxybenzoyl)-4...)
Affinity DataIC50:  336nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Universitat De Barcelona

US Patent
LigandPNGBDBM298353((S)-1-((2S,4S)-1-(4-(benzyloxy)-3,5-dimethoxybenzo...)
Affinity DataIC50:  339nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Universitat De Barcelona

US Patent
LigandPNGBDBM298361((S)-1-((2S)-1-(4-acetoxy-3,5-dimethoxybenzoyl)-4,4...)
Affinity DataIC50:  352nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Universitat De Barcelona

US Patent
LigandPNGBDBM298369((S)-1-((S)-1-(3-(benzyloxy)benzoyl)-4,4-difluoropy...)
Affinity DataIC50:  487nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Universitat De Barcelona

US Patent
LigandPNGBDBM298360((S)-1-((2S,4R)-1-(4-(benzyloxy)-3,5-dimethoxybenzo...)
Affinity DataIC50:  668nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Universitat De Barcelona

US Patent
LigandPNGBDBM298367((S)-1-((2S)-1-(3-pivaloyloxy-4,5-dimethoxybenzoyl)...)
Affinity DataIC50:  2.14E+3nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Universitat De Barcelona

US Patent
LigandPNGBDBM298366((S)-1-((2S)-1-(3-acetoxy-4,5-dimethoxybenzoyl)-4,4...)
Affinity DataIC50:  5.60E+3nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent