Cell Reactant:
cPLA2 C2
Syringe Reactant:
BDBM14
Meas. Tech.:
ITC and CD
Entry Date.:
12/04/00
ΔG°:
-7.94±n/a (kcal/mole)
ΔH° :
-6.23±n/a (kJ/mole)
ΔHobs :
-6.23±n/a (kJ/mole)
ΔS° :
0.01±n/a (kJ/mole-K)
Comments:
taken from Xu, G., McDonagh, T., Yu, H., Nalefski, E. A., Clark, J. D., and Cumming, D. A. (1998) J. Mol. Biol. 280, 485-500
Citation
 Zheng, LKrishnamoorthi, RZolkiewski, MWang, X Distinct Ca2+ binding properties of novel C2 domains of plant phospholipase dalpha and beta. J Biol Chem 275:19700-6 (2000) [PubMed]  Article
Cell React
Name:
Cytosolic phospholipase A2
Synonyms:
Lysophospholipase | Phosphatidylcholine 2-acylhydrolase | Phospholipase A2 | Phospholipase A2 group IVA | cPLA2
Type:
Protein
Mol. Mass.:
85219.30
Organism:
Homo sapiens (Human)
Description:
P47712
Residue:
749
Sequence:
MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGAFGDMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMDANYVMDETLGTATFTVSSMKVGEKKEVPFIFNQVTEMVLEMSLEVCSCPDLRFSMALCDQEKTFRQQRKEHIRESMKKLLGPKNSEGLHSARDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYVAGLSGSTWYMSTLYSHPDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIGETLIHNRMNTTLSSLKEKVNTAQCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYGTFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQSRGSTMEEELENITTKHIVSNDSSDSDDESHEPKGTENEDAGSDYQSDNQASWIHRMIMALVSDSALFNTREGRAGKVHNFMLGLNLNTSYPLSPLSDFATQDSFDDDELDAAVADPDEFERIYEPLDVKSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMNKLPFPKIDPYVFDREGLKECYVFKPKNPDMEKDCPTIIHFVLANINFRKYRAPGVPRETEEEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMHFNTLNNIDVIKEAMVESIEYRRQNPSRCSVSLSNVEARRFFNKEFLSKPKA
  
Syringe React
Name:
BDBM14
Synonyms:
Ca2+ | calcium
Type:
Metal Ion
Emp. Form.:
Ca
Mol. Mass.:
40.077
SMILES:
[Ca++]
Structure:
Search PDB for entries with ligand similarity: