Reaction Details  Report a problem with these data
Cell Reactant:
HyHEL-10 Mutant (HY58F)
Syringe Reactant:
Lysozyme (turkey egg)
Meas. Tech.:
ITC
Entry Date.:
2000-12-20
ΔG°:
-49.6000±n/a (kJ/mole)
pH:
7.2000±n/a
Temperature:
308.0000±n/a (K)
ΔH° :
-111.2000±n/a (kJ/mole)
ΔHobs :
-111.2000±n/a (kJ/mole)
ΔCp :
-2.6800±n/a (kJ/mole)
ΔS° :
-0.2000±n/a (kJ/mole-K)
Citation
 Nishimiya, Y; Tsumoto, K; Shiroishi, M; Yutani, K; Kumagai, I Thermodynamic consequences of grafting enhanced affinity toward the mutated antigen onto an antibody. The case of anti-lysozyme antibody, HyHEL-10. J Biol Chem 275:12813-20 (2000) [PubMed]  Article
Cell React
Source:
Described in Rajpal, A., Taylor, M. G., and Kirsch, J. F. (1998) Protein Sci. 7, 1868-1874.
Name:
HyHEL-10 Mutant (HY58F)
Synonyms:
n/a
Type:
Antibody
Mol. Mass.:
12768.84
Organism:
Mouse
Description:
Mutation in heavy chain of HyHEL-10
Residue:
114
Sequence:
DVQLQESGPSLVKPSQTLSLTCSVTGDSITSDYWSWIRKFPGNRLEYMGYVSYSGSTFYNPSLKSRISITRDTSKNQYYLDLNSVTTEDTATYYCANWDGDYWGQGTLVTVSAA
  
Syringe React
Source:
Sigma
Name:
Lysozyme (turkey egg)
Synonyms:
turkey egg lysozyme (TEL) | LYSC_MELGA | LYZ
Type:
Enzyme
Mol. Mass.:
16145.52
Organism:
Wild turkey
Description:
P00703
Residue:
147
Sequence:
MRSLLILVLCFLPLAALGKVYGRCELAAAMKRLGLDNYRGYSLGNWVCAAKFESNFNTHATNRNTDGSTDYGILQINSRWWCNDGRTPGSKNLCNIPCSALLSSDITASVNCAKKIASGGNGMNAWVAWRNRCKGTDVHAWIRGCRL