Reaction Details  Report a problem with these data
Cell Reactant:
Induced myeloid leukemia cell differentiation protein Mcl-1 (aa 172-327)
Syringe Reactant:
BDBM50400181
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
2014-03-20
ΔG°:
-32.7000±0.0000 (kJ/mole)
pH:
8.0000±0.0000
Temperature:
298.1500±0.0000 (K)
ΔH° :
-22.4000±0.0000 (kJ/mole)
ΔS° :
0.0345±0.0000 (kJ/mole-K)
Citation
 Zhang, Z; Zhao, Y; Song, T; Liu, Y; Li, X; Su, P; Xie, S Study of binding thermodynamics in the optimization of BH3 mimetics. Chem Biol Drug Des 82:394-400 (2013) [PubMed]  Article 
Cell React
Name:
Induced myeloid leukemia cell differentiation protein Mcl-1 [172-327]
Synonyms:
Mcl-1 (aa 172-327) | Mcl-1 (residues 172-327) | Induced myeloid leukemia cell differentiation protein Mcl-1 (aa 172-327) | MCL1_HUMAN | MCL1 | BCL2L3
Type:
n/a
Mol. Mass.:
17768.02
Organism:
Human
Description:
Q07820[172-327]
Residue:
156
Sequence:
DELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEGG
  
Syringe React
Name:
BDBM50400181
Synonyms:
CHEMBL2180321 | 6‐bromo‐2,3‐dihydroxyanthracene‐9,10‐dione (Ligand 3)
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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